Jamie Lopez

发表

Failed CTL/NK cell killing and cytokine hypersecretion are directly linked through prolonged synapse time

J. Trapani, I. Voskoboinik, S. Mannering, 2015, The Journal of experimental medicine.

Lipid order and charge protect killer T cells from accidental death

J. Trapani, B. Hoogenboom, Adrian W Hodel, 2019, Nature Communications.

The RabGAP TBC 1 D 1 Plays a Central Role in Exercise-Regulated Glucose Metabolism in Skeletal Muscle

Nolan J. Hoffman, D. James, G. Cooney, 2015 .

The RabGAP TBC1D1 Plays a Central Role in Exercise-Regulated Glucose Metabolism in Skeletal Muscle

Nolan J. Hoffman, D. James, G. Cooney, 2015, Diabetes.

Delivery at the Cytotoxic Immune Synapse Rapid and Unidirectional Perforin Pore

J. Trapani, A. Brennan, I. Voskoboinik, 2013 .

facilitate rapid access of granzymes during killer cell attack Perforin forms transient pores on the target cell plasma membrane to

J. Whisstock, H. Saibil, J. Trapani, 2013 .

The RalA GTPase Is a Central Regulator of Insulin Exocytosis from Pancreatic Islet Beta Cells*

D. James, H. Gaisano, E. Kwan, 2008, Journal of Biological Chemistry.

Snapin Interacts with the Exo70 Subunit of the Exocyst and Modulates GLUT4 Trafficking*

D. James, W. Hunziker, Yiqun Bao, 2008, Journal of Biological Chemistry.

Deciphering the syntax of cytotoxic lymphocyte degranulation

I. Voskoboinik, Jamie Lopez, 2013, European journal of immunology.

Defining the interaction of perforin with calcium and the phospholipid membrane.

J. Whisstock, J. Trapani, A. Brennan, 2013, The Biochemical journal.

RalA GTPase Tethers Insulin Granules to L‐ and R‐Type Calcium Channels Through Binding α2δ‐1 Subunit

D. James, T. Liang, S. Chidambaram, 2013, Traffic.

Protecting a serial killer: pathways for perforin trafficking and self-defence ensure sequential target cell death.

J. Whisstock, J. Trapani, A. Brennan, 2012, Trends in immunology.

Perforin forms transient pores on the target cell plasma membrane to facilitate rapid access of granzymes during killer cell attack.

Helen R Saibil, Olivia Susanto, James C Whisstock, 2013, Blood.

Exploration of a Series of 5-Arylidene-2-thioxoimidazolidin-4-ones as Inhibitors of the Cytolytic Protein Perforin

J. A. Spicer, W. Denny, J. Trapani, 2013, Journal of medicinal chemistry.

Regulation of the Endosomal SNARE Protein Syntaxin 7 by Colony-Stimulating Factor 1 in Macrophages

David E. James, John A. Hamilton, M. Sweet, 2008, Molecular and Cellular Biology.

Identification of a distal GLUT4 trafficking event controlled by actin polymerization.

Katarina Mele, Pascal Vallotton, David E James, 2009, Molecular biology of the cell.

Fatal immune dysregulation due to a gain of glycosylation mutation in lymphocyte perforin.

J. Trapani, A. Brennan, I. Voskoboinik, 2012, Blood.

Bi-Allelic Mutations in STXBP2 Reveal a Complementary Role for STXBP1 in Cytotoxic Lymphocyte Killing

N. Brown, J. Trapani, I. Voskoboinik, 2018, Front. Immunol..

Protection from endogenous perforin: glycans and the C terminus regulate exocytic trafficking in cytotoxic lymphocytes.

Olivia Susanto, James C Whisstock, Hideo Yagita, 2011, Immunity.

lymphocyte perforin Fatal immune dysregulation due to a gain of glycosylation mutation in

J. Trapani, A. Brennan, I. Voskoboinik, 2013 .

Molecular Dissection of the Munc18c/Syntaxin4 Interaction: Implications for Regulation of Membrane Trafficking

D. James, Jennifer L. Martin, C. Gee, 2006, Traffic.

Rapid and Unidirectional Perforin Pore Delivery at the Cytotoxic Immune Synapse

J. Trapani, A. Brennan, J. Lopez, 2013, The Journal of Immunology.

Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytes.

D. James, J. Lopez, G. Ramm, 2008, Cell metabolism.

Exocytotic Vesicle Behaviour Assessed by Total Internal Reflection Fluorescence Microscopy

P. Vallotton, K. Mele, W. E. Hughes, 2010, Traffic.

Variations in the requirement for v-SNAREs in GLUT4 trafficking in adipocytes

D. James, J. Burchfield, W. Hong, 2009, Journal of Cell Science.

Comparative studies of Munc18c and Munc18-1 reveal conserved and divergent mechanisms of Sec1/Munc18 proteins

D. James, Jennifer L. Martin, Jingshi Shen, 2013, Proceedings of the National Academy of Sciences.

Defining the interaction of perforin with calcium and the phospholipid membrane.

J. Whisstock, J. Trapani, A. Brennan, 2013, The Biochemical journal.

Deciphering the syntax of cytotoxic lymphocyte degranulation

I. Voskoboinik, Jamie Lopez, 2013, European journal of immunology.