E. Lorimer

发表

Splice switching an oncogenic ratio of SmgGDS isoforms as a strategy to diminish malignancy

Carol L. Williams, M. Distefano, F. Rigo, 2020, Proceedings of the National Academy of Sciences.

β-Adrenergic receptors suppress Rap1B prenylation and promote the metastatic phenotype in breast cancer cells

Carol L. Williams, E. Lorimer, Michael D. Tyburski, 2015, Cancer biology & therapy.

An Adenosine-Mediated Signaling Pathway Suppresses Prenylation of the GTPase Rap1B and Promotes Cell Scattering

Carol L. Williams, B. Kalyanaraman, J. Auchampach, 2013, Science Signaling.

Splice Variants of SmgGDS Control Small GTPase Prenylation and Membrane Localization

Carol L. Williams, A. Fields, Rongshan Li, 2010, The Journal of Biological Chemistry.

Rap1A, Rap1B, and β-Adrenergic Signaling in Autologous HCT: A Randomized Controlled Trial of Propranolol

Carol L. Williams, P. Hari, A. Szabo, 2022, The Yale journal of biology and medicine.

SmgGDS Regulates Cell Proliferation, Migration, and NF-κB Transcriptional Activity in Non-small Cell Lung Carcinoma*

Carol L. Williams, Rongshan Li, G. Tew, 2008, Journal of Biological Chemistry.

SmgGDS is a transient nucleolar protein that protects cells from nucleolar stress and promotes the cell cycle by regulating DREAM complex gene expression

H. Rui, S. Tsaih, M. Flister, 2017, Oncogene.

SmgGDS-558 regulates the cell cycle in pancreatic, non-small cell lung, and breast cancers

Carol L. Williams, Adam J. Gastonguay, E. Lorimer, 2014, Cell cycle.

The role of Rac1 in the regulation of NF-kB activity, cell proliferation, and cell migration in non-small cell lung carcinoma

Carol L. Williams, Adam J. Gastonguay, Tracy J. Berg, 2012, Cancer biology & therapy.

The Chaperone Protein SmgGDS Interacts with Small GTPases Entering the Prenylation Pathway by Recognizing the Last Amino Acid in the CAAX Motif*

Carol L. Williams, M. Distefano, J. Barbieri, 2014, The Journal of Biological Chemistry.

She2p is a novel RNA‐binding protein that recruits the Myo4p–She3p complex to ASH1 mRNA

R. Singer, P. Chartrand, Wei Gu, 2000, The EMBO journal.

Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer

Carol L. Williams, J. Rosenfeld, G. Getz, 2019, Nature Genetics.

The SmgGDS Splice Variant SmgGDS-558 Is a Key Promoter of Tumor Growth and RhoA Signaling in Breast Cancer

Carol L. Williams, A. Mackinnon, Jian Huang, 2013, Molecular Cancer Research.

Differences in the Phosphorylation-Dependent Regulation of Prenylation of Rap1A and Rap1B.

Carol L. Williams, J. Prokop, E. Lorimer, 2016, Journal of molecular biology.

The Tumor-suppressive Small GTPase DiRas1 Binds the Noncanonical Guanine Nucleotide Exchange Factor SmgGDS and Antagonizes SmgGDS Interactions with Oncogenic Small GTPases*

Carol L. Williams, C. Fierke, Kathleen R. Noon, 2016, The Journal of Biological Chemistry.

GTPase splice variants RAC1 and RAC1B display isoform-specific differences in localization, prenylation, and interaction with the chaperone protein SmgGDS

Carol L. Williams, M. Distefano, K. Suazo, 2023, The Journal of biological chemistry.

Structural and biophysical properties of farnesylated KRas interacting with the chaperone SmgGDS-558.

Carol L. Williams, A. Grishaev, M. Lösche, 2022, Biophysical journal.

Mutations in RABL3 alter KRAS prenylation and are associated with hereditary pancreatic cancer

Carol L. Williams, J. Rosenfeld, G. Getz, 2019, Nature Genetics.

The Chaperone Protein SmgGDS Interacts with Small GTPases Entering the Prenylation Pathway by Recognizing the Last Amino Acid in the CAAX Motif*

Carol L. Williams, M. Distefano, J. Barbieri, 2014, Journal of Biological Chemistry.

Differences in the Phosphorylation-Dependent Regulation of Prenylation of Rap1A and Rap1B.

Carol L. Williams, J. Prokop, E. Lorimer, 2016, Journal of molecular biology.