B. Carbain

发表

‘TamiGold’: phospha-oseltamivir-stabilised gold nanoparticles as the basis for influenza therapeutics and diagnostics targeting the neuraminidase (instead of the hemagglutinin)

R. Field, A. Rashid, Stephen R. Martin, 2012 .

Trifluoroacetic acid in 2,2,2-trifluoroethanol facilitates S(N)Ar reactions of heterocycles with arylamines.

I. Hardcastle, R. Griffin, B. Golding, 2014, Chemistry.

Biotin-, fluorescein- and 'clickable' conjugates of phospha-oseltamivir as probes for the influenza virus which utilize selective binding to the neuraminidase.

Stephen R. Martin, M. Stanley, B. Carbain, 2011, Organic & biomolecular chemistry.

New aspects of the Hunsdiecker–Barton halodecarboxylation—syntheses of phospha-shikimic acid and derivatives

P. Hitchcock, B. Carbain, H. Streicher, 2010 .

Galactose-conjugates of the oseltamivir pharmacophore--new tools for the characterization of influenza virus neuraminidases.

P. Collins, P. Hitchcock, Stephen R. Martin, 2009, Organic & biomolecular chemistry.

Efficient Synthesis of Highly Active Phospha‐Isosteres of the Influenza Neuraminidase Inhibitor Oseltamivir

P. Collins, Stephen R. Martin, A. Hay, 2009, ChemMedChem.

Solid-Phase Synthesis of 3,4-Dihydroquinoxalin-2(1H)-ones via the Cyclative Cleavage of N-Arylated Carboxamides

V. Krchňák, Eva Schütznerová, A. Přibylka, 2016 .

Preparation of 3,4-Substituted-5-Aminopyrazoles and 4-Substituted-2-Aminothiazoles.

K. Paruch, P. Khirsariya, B. Carbain, 2018, The Journal of organic chemistry.

Cyclin-Dependent Kinase (CDK) Inhibitors: Structure–Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines

M. Noble, J. Endicott, I. Hardcastle, 2016, Journal of medicinal chemistry.

Regioselective sulfamoylation at low temperature enables concise syntheses of putative small molecule inhibitors of sulfatases.

H. Reeves, R. Griffin, B. Golding, 2015, Organic & biomolecular chemistry.

2-Arylamino-6-ethynylpurines are cysteine-targeting irreversible inhibitors of Nek2 kinase

I. Hardcastle, R. Griffin, B. Golding, 2020, RSC medicinal chemistry.

Cyclin-Dependent Kinase (CDK) Inhibitors: Structure−Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substitued 2-Arylaminopurines

M. Noble, J. Endicott, I. Hardcastle, 2017 .

Trifluoroethanol solvent facilitates selective N-7 methylation of purines.

I. Hardcastle, R. Griffin, B. Golding, 2013, Organic & biomolecular chemistry.

8-Substituted O(6)-cyclohexylmethylguanine CDK2 inhibitors: using structure-based inhibitor design to optimize an alternative binding mode.

D. Paterson, M. Noble, J. Endicott, 2014, Journal of medicinal chemistry.

Model system for irreversible inhibition of Nek2: thiol addition to ethynylpurines and related substituted heterocycles.

I. Hardcastle, R. Griffin, B. Golding, 2014, Organic & biomolecular chemistry.

Explicit treatment of active-site waters enhances quantum mechanical/implicit solvent scoring: Inhibition of CDK2 by new pyrazolo[1,5-a]pyrimidines.

K. Paruch, V. Kryštof, P. Hobza, 2017, European journal of medicinal chemistry.

Structure-Based Design of Potent and Orally Active Isoindolinone Inhibitors of MDM2-p53 Protein-Protein Interaction.

M. Noble, J. Endicott, G. Chessari, 2021, Journal of medicinal chemistry.

118 2-arylamino-6-ethynylpurines as Potent Irreversible Inhibitors of the Mitotic Kinase Nek2

R. Griffin, K. Boxall, R. Bayliss, 2012 .

Cyclin-Dependent Kinase (CDK) Inhibitors: Structure–Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines

M. Noble, J. Endicott, I. Hardcastle, 2016, Journal of medicinal chemistry.

Explicit treatment of active-site waters enhances quantum mechanical/implicit solvent scoring: Inhibition of CDK2 by new pyrazolo[1,5-a]pyrimidines.

K. Paruch, V. Kryštof, P. Hobza, 2017, European journal of medicinal chemistry.

Regioselective sulfamoylation at low temperature enables concise syntheses of putative small molecule inhibitors of sulfatases.

H. Reeves, R. Griffin, B. Golding, 2015, Organic & biomolecular chemistry.