Lauren V. C. Miller

Cholesterol determines the cytosolic entry and seeded aggregation of tau

L. James, E. Metzakopian, M. Vaysburd, 2022, Cell reports.

Tau assemblies enter the cytosol in a cholesterol sensitive process essential to seeded aggregation

L. James, E. Metzakopian, M. Vaysburd, 2021, bioRxiv.

Tau assemblies enter the cytosol of neurons in a cholesterol sensitive manner

L. James, M. Vaysburd, W. McEwan, 2021 .

Cytosolic antibody receptor TRIM21 is required for effective tau immunotherapy in mouse models

M. Goedert, J. Andersen, L. James, 2023, Science.

Tau assemblies do not behave like independently acting prion-like particles in mouse neural tissue

L. James, M. Coleman, M. Vaysburd, 2021, bioRxiv.

The type‐I interferon response potentiates seeded tau aggregation and exacerbates tau pathology

M. Vaysburd, W. McEwan, Benjamin J. Tuck, 2023, Alzheimer's & dementia : the journal of the Alzheimer's Association.