B. O’Malley

发表

Defining the mammalian coactivation of hepatic 12-h clock and lipid metabolism

S. Jung, N. Putluri, Bokai Zhu, 2022, Cell reports.

A novel endocrine-disrupting agent in corn with mitogenic activity in human breast and prostatic cancer cells.

R. Faith, S. Mani, B. Markaverich, 2002, Environmental health perspectives.

A steroid receptor coactivator small molecule “stimulator” attenuates post-stroke ischemic brain injury

C. Dacso, T. Lazaro, D. Lonard, 2022, Frontiers in Molecular Neuroscience.

Dopaminergic Regulation of Progesterone Receptors: Brain D5 Dopamine Receptors Mediate Induction of Lordosis by D1-Like Agonists in Rats

S. Watson, Carolyn L. Smith, J. Garai, 1996, The Journal of Neuroscience.

The Steroid Receptor Coactivator-1 Contains Multiple Receptor Interacting and Activation Domains That Cooperatively Enhance the Activation Function 1 (AF1) and AF2 Domains of Steroid Receptors*

D. Edwards, M. Tsai, T. Spencer, 1998, The Journal of Biological Chemistry.

USP15-dependent lysosomal pathway controls p53-R175H turnover in ovarian cancer cells

K. Wong, J. Richards, D. Lonard, 2018, Nature Communications.

Activation of mTORC1 and c-Jun by Prohibitin1 loss in Schwann cells may link mitochondrial dysfunction to demyelination

L. Wrabetz, E. Hurley, E. Wilson, 2021, eLife.

Conservation of copy number profiles during engraftment and passaging of patient-derived cancer xenografts

Yvonne A. Evrard, Michael W. Lloyd, Jeffrey H. Chuang, 2021, Nature Genetics.

The Angelman Syndrome-Associated Protein, E6-AP, Is a Coactivator for the Nuclear Hormone Receptor Superfamily

M. Tsai, Z. Nawaz, S. Tsai, 1999, Molecular and Cellular Biology.

Emerging roles of the ubiquitin proteasome system in nuclear hormone receptor signaling.

D. Lonard, Bert W. O’Malley, B. O’Malley, 2009, Progress in molecular biology and translational science.

p300 Requires Its Histone Acetyltransferase Activity and SRC-1 Interaction Domain To Facilitate Thyroid Hormone Receptor Activation in Chromatin

J. Wong, Jiwen Li, Bert W. O’Malley, 2000, Molecular and Cellular Biology.

Decidualization of human endometrial stromal cells requires steroid receptor coactivator-3

F. DeMayo, J. Lydon, Maria M. Szwarc, 2022, Frontiers in Reproductive Health.

Ligand-Mediated Assembly and Real-Time Cellular Dynamics of Estrogen Receptor α-Coactivator Complexes in Living Cells

Anne E Carpenter, A. Belmont, Carolyn L. Smith, 2001, Molecular and Cellular Biology.

Steroid receptor coactivators – their role in immunity

D. Lonard, Bert W. O’Malley, B. O’Malley, 2022, Frontiers in Immunology.

Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment

D. Lonard, Bert W. O’Malley, N. Sung, 2022, Breast Cancer Research.

Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer

Eric A. Smith, Sean M. Hartig, K. Rajapakshe, 2018, Nature Metabolism.

Mitochondrial pyruvate import is a metabolic vulnerability in androgen receptor-driven prostate cancer

Eric A. Smith, Sean M. Hartig, K. Rajapakshe, 2018, Nature Metabolism.

REGγ deficiency promotes premature aging via the casein kinase 1 pathway

L. Donehower, Jian Luo, Honglin Luo, 2013, Proceedings of the National Academy of Sciences.

Regulation of SRC-3 Intercompartmental Dynamics by Estrogen Receptor and Phosphorylation

Adam T. Szafran, M. Mancini, V. Berno, 2007, Molecular and Cellular Biology.

Development of improved SRC-3 inhibitors as breast cancer therapeutic agents.

Jianming Xu, D. Lonard, Prashi Jain, 2021, Endocrine-related cancer.

Steroid Receptor Coactivator (SRC) Family: Masters of Systems Biology*

Brian York, Bert W. O'Malley, B. York, 2010, The Journal of Biological Chemistry.

Mice deficient in the steroid receptor co‐activator 1 (SRC‐1) are resistant to thyroid hormone

R. Weiss, S. Refetoff, Bert W. O’Malley, 1999, The EMBO journal.

Progesterone involvement in breast development and tumorigenesis—as revealed by progesterone receptor “knockout” and “knockin” mouse models

F. DeMayo, S. Soyal, J. Lydon, 2003, Steroids.

ERK3 Promotes Endothelial Cell Functions by Upregulating SRC‐3/SP1‐Mediated VEGFR2 Expression

S. Vallabhaneni, R. Wu, Weiwen Long, 2014, Journal of cellular physiology.

Loss of Orphan Receptor Germ Cell Nuclear Factor Function Results in Ectopic Development of the Tail Bud and a Novel Posterior Truncation

A. Cooney, F. DeMayo, A. Chung, 2001, Molecular and Cellular Biology.

Streamlined analysis schema for high-throughput identification of endogenous protein complexes

Y. Wang, A. Malovannaya, Y. Li, 2010, Proceedings of the National Academy of Sciences.

Title : HER 2 signaling drives DNA anabolism and proliferation through SRC-3 phosphorylation and E 2 F 1-regulated genes

S. Hilsenbeck, C. Creighton, R. Lanz, 2016 .

8-Bromo-Cyclic AMP Induces Phosphorylation of Two Sites in SRC-1 That Facilitate Ligand-Independent Activation of the Chicken Progesterone Receptor and Are Critical for Functional Cooperation between SRC-1 and CREB Binding Protein

N. Weigel, B. Rowan, Bert W. O’Malley, 2000, Molecular and Cellular Biology.

Progesterone Regulates Proliferation of Endothelial Cells*

D. Edwards, M. Iruela-Arispe, J. Lydon, 1999, The Journal of Biological Chemistry.

An estrogen receptor alpha activity indicator model in mice

F. DeMayo, B. O’Malley, Sang Jun Han, 2009, Genesis.

Progesterone and its metabolites increase myelin basic protein expression in organotypic slice cultures of rat cerebellum

M. Schumacher, A. Ghoumari, B. O’Malley, 2003, Journal of neurochemistry.

Nuclear Receptors, Coregulators, Ligands, and Selective Receptor Modulators

N. McKenna, B. O’Malley, NEIL J. McKENNA, 2001, Annals of the New York Academy of Sciences.

Oleuropein suppresses endometriosis progression and improves the fertility of mice with endometriosis

M. Park, W. Gibbons, Bert W. O’Malley, 2022, Journal of Biomedical Science.

E2/Estrogen Receptor/Sjogren Syndrome-Associated Autoantigen Relieves Coactivator Activator-Induced G1/S Arrest To Promote Breast Tumorigenicity

S. Jung, M. Tsai, S. Tsai, 2014, Molecular and Cellular Biology.

Advances in Brief Inhibition of Estrogen Receptor Action by a Naturally Occurring Variant in Human Breast Tumors 1

W. McGuire, S. Fuqua, R. Elledge, 2006 .

Steroid receptor coactivator 3 is a key modulator of regulatory T cell–mediated tumor evasion

R. Lanz, C. Dacso, Yan Xia, 2023, Proceedings of the National Academy of Sciences of the United States of America.

Steroid receptor coactivator 3 is a key modulator of regulatory T cell–mediated tumor evasion

R. Lanz, C. Dacso, Yan Xia, 2023, bioRxiv.

Inhibition of SRC-3 as a potential therapeutic strategy for aggressive mantle cell lymphoma

L. Alinari, Jing Chen, D. Lonard, 2023, Research square.

Steroid receptor coactivator 2 is essential for progesterone-dependent uterine function and mammary morphogenesis: Insights from the mouse—implications for the human

F. DeMayo, J. Lydon, P. Amato, 2006, The Journal of Steroid Biochemistry and Molecular Biology.

Results of a Search for the Mechanisms of Steroid Receptor Regulation of Gene Expression

B. O’Malley, 2004, Annals of the New York Academy of Sciences.

Aging-associated REGγ proteasome decline predisposes to tauopathy

R. Moses, Xiaotao Li, Liangcai Gao, 2022, The Journal of biological chemistry.

Hypothalamic steroid receptor coactivator-2 regulates adaptations to fasting and overnutrition

M. Fukuda, Zheng Sun, Yong Xu, 2021, Cell reports.

PDX-1 Is a Therapeutic Target for Pancreatic Cancer, Insulinoma and Islet Neoplasia Using a Novel RNA Interference Platform

R. Gibbs, D. Rao, N. Senzer, 2012, PloS one.

Mice lacking progesterone receptor exhibit pleiotropic reproductive abnormalities.

B. O’Malley, C. A. Montgomery, F. DeMayo, 1995, Genes & development.