Fumihisa Isomura

In vivo validation of the switch antibody concept: SPECT/CT imaging of the anti-CD137 switch antibody Sta-MB shows high uptake in tumors but low uptake in normal organs in human CD137 knock-in mice

A. Tsuji, A. Sugyo, H. Sudo, 2022, Translational oncology.

Antibody to CD137 activated by extracellular adenosine triphosphate is tumor selective and broadly effective in vivo without systemic immune activation.

K. Jishage, O. Ueda, S. Kadono, 2020, Cancer discovery.