L. Brown

发表

Design and synthesis of novel proline based factor XIa selective inhibitors as leads for potential new anticoagulants.

B. Hawes, Zhuyan Guo, W. Geissler, 2020, Bioorganic & medicinal chemistry letters.

The discovery of orally available thrombin inhibitors: studies towards the optimisation of CGH1668.

D. Janus, K. Menear, David J. Farr, 1998, Bioorganic & medicinal chemistry letters.

Studies towards the identification of potent, selective and bioavailable thrombin inhibitors.

D. Janus, K. Menear, D. Bentley, 1999, Bioorganic & medicinal chemistry letters.

A three-step tandem process for the synthesis of bicyclic gamma-lactams.

A. Cooke, A. Sutherland, Fiona I. McGonagle, 2010, Organic & biomolecular chemistry.

The design and synthesis of thrombin inhibitors: analogues of MD805 containing non-polar surrogates for arginine at the P1 position.

D. Brundish, D. Janus, X. Cockcroft, 2000, Bioorganic & medicinal chemistry letters.

The Cardiovascular Nutrapharmacology of Resveratrol: Pharmacokinetics, Molecular Mechanisms and Therapeutic Potential

P. Kroon, A. Iyer, P. Chunduri, 2010, Current medicinal chemistry.

Microwave-promoted tandem reactions for the synthesis of bicyclic γ-lactams

A. Cooke, A. Sutherland, Fiona I. McGonagle, 2011 .

The discovery of orally available thrombin inhibitors: optimisation of the P1 pharmacophore.

B. Wathey, D. Janus, K. Menear, 1999, Bioorganic & medicinal chemistry letters.

Discovery of Benzimidazole CYP11B2 Inhibitors with in Vivo Activity in Rhesus Monkeys.

Michael E. Lassman, Jeffrey T. Kuethe, M. Struthers, 2015, ACS medicinal chemistry letters.

Optimisation of the P2 pharmacophore in a series of thrombin inhibitors: ion-dipole interactions with lysine 60G.

M. Grütter, J. Priestle, B. Wathey, 1999, Bioorganic & Medicinal Chemistry Letters.