C. Loucera

发表

Mechanistic modeling of the SARS-CoV-2 disease map

Marta R. Hidalgo, J. Dopazo, C. Çubuk, 2020, BioData Mining.

Assessing the Impact of SARS-CoV-2 Lineages and Mutations on Patient Survival

J. Dopazo, J. Rodríguez-Baño, J. Lepe, 2022, medRxiv.

Real-world evidence with a retrospective cohort of 15,968 Andalusian COVID-19 hospitalized patients suggests 21 new effective treatments and one drug that increases death risk.

M. Peña-Chilet, C. Loucera, G. Bostelmann, 2022, medRxiv.

Mechanistic models of signaling pathways deconvolute the glioblastoma single-cell functional landscape

Marta R. Hidalgo, J. Dopazo, M. Hidalgo, 2020, NAR cancer.

Antibiotic resistance and metabolic profiles as functional biomarkers that accurately predict the geographic origin of city metagenomics samples

J. P. Florido, J. Dopazo, Carlos Loucera, 2018, bioRxiv.

Integrating prior knowledge in neural network methods to reduce the dimensions of single-cell RNA-Seq Data

Isabel A. Nepomuceno-Chamorro, J. Dopazo, C. Loucera, 2020 .

Antibiotic resistance and metabolic profiles as functional biomarkers that accurately predict the geographic origin of city metagenomics samples

J. Dopazo, Carlos Loucera, C. S. Casimiro-Soriguer, 2018, bioRxiv.

Using mechanistic models for the clinical interpretation of complex genomic variation

Marta R. Hidalgo, J. Dopazo, M. Hidalgo, 2019, Scientific Reports.

Interpretable machine learning analysis of functional metagenomic profiles improves colorectal cancer prediction and reveals basic molecular mechanisms.

J. Dopazo, M. Peña-Chilet, Carlos Loucera, 2020 .

Mechanistic models of signaling pathways deconvolute the functional landscape of glioblastoma at single cell resolution

Marta R. Hidalgo, J. Dopazo, M. Hidalgo, 2019, bioRxiv.

DNA Based Methods in Intelligence - Moving Towards Metagenomics

Pawel P. Labaj, Alexandra B. Graf, C. Mason, 2020 .

Discovering potential interactions between rare diseases and COVID-19 by combining mechanistic models of viral infection with statistical modeling

J. Dopazo, M. Peña-Chilet, C. Loucera, 2022, Human molecular genetics.

Integrating pathway knowledge with deep neural networks to reduce the dimensionality in single-cell RNA-seq data

Carlos Loucera, Pelin Gundogdu, Inmaculada Alamo-Alvarez, 2021, BioData Mining.

Exploring the druggable space around the Fanconi anemia pathway using machine learning and mechanistic models

J. Dopazo, M. Peña-Chilet, C. Loucera, 2019, bioRxiv.

From partial to whole genome imputation of SARS-CoV-2 for epidemiological surveillance

J. Dopazo, J. Lepe, Pedro Martinez, 2021, bioRxiv.

Exploring the druggable space around the Fanconi anemia pathway using machine learning and mechanistic models

Carlos Loucera, Marina Esteban-Medina, Joaquín Dopazo, 2019, BMC Bioinformatics.

Towards a metagenomics machine learning interpretable model for understanding the transition from adenoma to colorectal cancer

J. Dopazo, M. Peña-Chilet, C. S. Casimiro-Soriguer, 2022, Scientific Reports.

Towards a metagenomics machine learning interpretable model for understanding the transition from adenoma to colorectal cancer

Carlos Loucera, Joaquin Dopazo, Carlos S Casimiro-Soriguer, 2021, Scientific Reports.

Genome-scale mechanistic modeling of signaling pathways made easy: A bioconductor/cytoscape/web server framework for the analysis of omic data

Marta R. Hidalgo, J. Dopazo, C. Çubuk, 2021, Computational and structural biotechnology journal.

SMN1 copy‐number and sequence variant analysis from next‐generation sequencing data

J. Dopazo, Daniel López-López, Ángel Alonso, 2020, bioRxiv.

An SPM-Enriched Marine Oil Supplement Shifted Microglia Polarization toward M2, Ameliorating Retinal Degeneration in rd10 Mice

A. Martínez-Romero, M. Peña-Chilet, G. Puras, 2022, Antioxidants.

A Mechanistic Model for Genome-Scale Estimations of Metabolic Activity

Marta R. Hidalgo, J. Dopazo, A. Amadoz, 2021 .

Using mechanistic models for the clinical interpretation of complex genomic variation

Marta R. Hidalgo, J. Dopazo, M. Peña-Chilet, 2019, Scientific Reports.

CSVS, a crowdsourcing database of the Spanish population genetic variability

Carlos Loucera, Joaquín Dopazo, Aurora Pujol, 2020, Nucleic Acids Res..

Simulated Annealing Algorithm for Bezier Curve Approximation

Andrés Iglesias, Akemi Gálvez, Carlos Loucera, 2014, 2014 International Conference on Cyberworlds.

Simulated Annealing Algorithm for B´ ezier Curve Approximation

C. Loucera, 2014 .

Lévy Flight-Driven Simulated Annealing for B-spline Curve Fitting

Andrés Iglesias, Akemi Gálvez, Carlos Loucera, 2018 .

Real world evidence of calcifediol or vitamin D prescription and mortality rate of COVID-19 in a retrospective cohort of hospitalized Andalusian patients

J. Dopazo, R. Bouillon, J. López-Miranda, 2021, Scientific Reports.

Real world evidence of calcifediol use and mortality rate of COVID-19 hospitalized in a large cohort of 16,401 Andalusian patients

J. Dopazo, R. Bouillon, J. López-Miranda, 2021, medRxiv.

SigPrimedNet: A Signaling-Informed Neural Network for scRNA-seq Annotation of Known and Unknown Cell Types

Isabel A. Nepomuceno-Chamorro, J. Dopazo, C. Loucera, 2023, Biology.

Automatic calculation of bicycle routes by combining meta-heuristics and GIS techniques within the framework of smart cities

Oscar Cosido, Carlos Loucera, Andres Iglesias, 2013, 2013 International Conference on New Concepts in Smart Cities: Fostering Public and Private Alliances (SmartMILE).

Memetic Simulated Annealing for Data Approximation with Local-Support Curves

Andrés Iglesias, Akemi Gálvez, Carlos Loucera, 2017, ICCS.

Drug repurposing for COVID-19 using machine learning and mechanistic models of signal transduction circuits related to SARS-CoV-2 infection

Carlos Loucera, Marina Esteban-Medina, Kinza Rian, 2020, Signal Transduction and Targeted Therapy.

Highly accurate whole-genome imputation of SARS-CoV-2 from partial or low-quality sequences

J. Dopazo, F. Ortuño, N. Chueca, 2021, GigaScience.

Crosstalk between Metabolite Production and Signaling Activity in Breast Cancer

J. Dopazo, C. Çubuk, M. Peña-Chilet, 2023, International journal of molecular sciences.

Evidence of the association between increased use of direct oral anticoagulants and a reduction in the rate of atrial fibrillation-related stroke and major bleeding at the population level (2012-2019).

Rosario Carmona, C. Loucera, G. Bostelmann, 2023, Medicina clinica.

Functional Profiling of Soft Tissue Sarcoma Using Mechanistic Models

M. Peña-Chilet, C. Loucera, M. Esteban-Medina, 2023, International journal of molecular sciences.

Simulated Annealing and Natural Neighbor for Rational Bézier Surface Reconstruction from Scattered Data Points

Andrés Iglesias, Akemi Gálvez, Carlos Loucera, 2017, ICHSA.

Real-world evidence with a retrospective cohort of 15,968 COVID-19 hospitalized patients suggests 21 new effective treatments

M. Peña-Chilet, Rosario Carmona, C. Loucera, 2023, Virology Journal.

drexml: A command line tool and Python package for drug repurposing

M. Peña-Chilet, C. Loucera, M. Esteban-Medina, 2024, Computational and structural biotechnology journal.

Mutational landscape of risk variants in comorbid depression and obesity: a next-generation sequencing approach.

Daniel López-López, E. Molina, C. Loucera, 2024, Molecular psychiatry.

Unveiling the Landscape of Reportable Genetic Secondary Findings in the Spanish Population: A Comprehensive Analysis Using the Collaborative Spanish Variant Server Database

M. Peña-Chilet, J. L. Fernandez-Rueda, Daniel López-López, 2024, medRxiv.

The mechanistic functional landscape of retinitis pigmentosa: a machine learning-driven approach to therapeutic target discovery

M. Peña-Chilet, Kinza Rian, L. Olivares-González, 2024, Journal of translational medicine.