C. Jiménez‐Cervantes

发表

N‐glycosylation of the human melanocortin 1 receptor: occupancy of glycosylation sequons and functional role

J. García-Borrón, Cecilia Herraiz, B. Sanchez-Laorden, 2011, Pigment cell & melanoma research.

Biosynthesis of hamster zona pellucida is restricted to the oocyte.

J. Ballesta, M. Avilés, L. Gimeno, 2011, Theriogenology.

Human melanocortin 1 receptor-mediated ubiquitination of nonvisual arrestins. Role of Mahogunin Ring Finger 1 E3 ligase.

J. García-Borrón, Cecilia Herraiz, María Castejón-Griñán, 2018, Biochimica et biophysica acta. Molecular cell research.

Inhibition of melanogenesis in response to oxidative stress: transient downregulation of melanocyte differentiation markers and possible involvement of microphthalmia transcription factor.

F. Solano, J. García-Borrón, N. Daum, 2001, Journal of cell science.

Melanocortin 1 receptor mutations impact differentially on signalling to the cAMP and the ERK mitogen‐activated protein kinase pathways

J. García-Borrón, Cecilia Herraiz, P. Zanna, 2009, FEBS letters.

Role of G protein-coupled receptor kinases in the homologous desensitization of the human and mouse melanocortin 1 receptors.

L. Guillo, J. García-Borrón, J. Sánchez-Más, 2003, Molecular endocrinology.

A new enzymatic function in the melanogenic pathway. The 5,6-dihydroxyindole-2-carboxylic acid oxidase activity of tyrosinase-related protein-1 (TRP1).

K. Urabe, V. Hearing, F. Solano, 1994, The Journal of biological chemistry.

G. Imokawa, K. Urabe, V. Hearing, 1994, The EMBO journal.

Molecular interactions within the melanogenic complex: formation of heterodimers of tyrosinase and TRP1 from B16 mouse melanoma.

F. Solano, J. García-Borrón, M. Martínez-Esparza, 1998, Biochemical and biophysical research communications.

The mouse silver locus encodes a single transcript truncated by the silver mutation

D. Bennett, F. Solano, J. García-Borrón, 1999, Mammalian Genome.

Aberrant trafficking of human melanocortin 1 receptor variants associated with red hair and skin cancer: Steady‐state retention of mutant forms in the proximal golgi

V. Hearing, J. García-Borrón, J. Valencia, 2009, Journal of cellular physiology.

Mechanism of dimerization of the human melanocortin 1 receptor.

A. B. Pérez-Oliva, J. García-Borrón, Cecilia Herraiz, 2008, Biochemical and biophysical research communications.

Dimerization of the human melanocortin 1 receptor: functional consequences and dominant-negative effects.

E. Martínez-Alonso, J. García-Borrón, J. Sánchez-Más, 2006, The Journal of investigative dermatology.

Melanin formation in the inner ear is catalyzed by a new tyrosine hydroxylase kinetically and structurally different from tyrosinase.

F. Solano, J. García-Borrón, A. Meyer zum Gottesberge, 1997, Biochimica et biophysica acta.

Biochemical characterization of the melanogenic system in the eye of adult rodents.

F. Solano, J. García-Borrón, J. Lozano, 1995, Biochimica et biophysica acta.

Effect of detergents and endogenous lipids on the activity and properties of tyrosinase and its related proteins.

F. Solano, J. García-Borrón, J. Lozano, 1995, Biochimica et biophysica acta.

The DHICA oxidase activity of the melanosomal tyrosinases LEMT and HEMT.

F. Solano, J. García-Borrón, J. Lozano, 1994, Pigment cell research.

Improved tyrosinase activity stains in polyacrylamide electrophoresis gels.

F. Solano, J. García-Borrón, J. Lozano, 1993, Pigment cell research.

Tyrosinase isoenzymes in mammalian melanocytes. 2. Differential activation by alpha-melanocyte-stimulating hormone.

F. Solano, J. García-Borrón, J. Lozano, 1993, European journal of biochemistry.

Preparation of purified tyrosinase devoid of dopachrome tautomerase from mammalian malignant melanocytes.

F. Solano, J. García-Borrón, J. Lozano, 1993, Pigment cell research.

Anti-inflammatory and anti-invasive effects of α-melanocyte-stimulating hormone in human melanoma cells

J. Haycock, G. Ghanem, J. García-Borrón, 2003, British Journal of Cancer.

Regulation of Human Melanocortin 1 Receptor Signaling and Trafficking by Thr-308 and Ser-316 and Its Alteration in Variant Alleles Associated with Red Hair and Skin Cancer*

J. García-Borrón, B. Sanchez-Laorden, C. Jiménez‐Cervantes, 2007, Journal of Biological Chemistry.

Mechanisms of melanogenesis inhibition by tumor necrosis factor-alpha in B16/F10 mouse melanoma cells.

F. Solano, J. García-Borrón, M. Martínez-Esparza, 1998, European journal of biochemistry.

The Pro162 variant is a loss-of-function mutation of the human melanocortin 1 receptor gene.

G. Ghanem, J. García-Borrón, R. Morandini, 2001, The Journal of investigative dermatology.

Molecular mechanism for catalysis by a new zinc-enzyme, dopachrome tautomerase.

J. H. Martinez‐Liarte, F. Solano, J. García-Borrón, 1996, The Biochemical journal.

Dopachrome tautomerase is a zinc-containing enzyme.

J. H. Martinez‐Liarte, F. Solano, J. García-Borrón, 1994, Biochemical and biophysical research communications.

Agonist-independent, high constitutive activity of the human melanocortin 1 receptor.

J. García-Borrón, J. Sánchez-Más, C. Hahmann, 2003, Pigment cell research.

Variant amino acids in different domains of the human melanocortin 1 receptor impair cell surface expression.

J. García-Borrón, J. Sánchez-Más, M. Turpin, 2006, Cellular and molecular biology.

Functional characterization of a C‐terminal splice variant of the human melanocortin 1 receptor

J. García-Borrón, Cecilia Herraiz, Idoya Martínez-Vicente, 2020, Experimental dermatology.

The 5,6-dihydroxyindole-2-carboxylic acid (DHICA) oxidase activity of human tyrosinase.

F. Solano, J. García-Borrón, C. Olivares, 2001, The Biochemical journal.

Tyrosinase isoenzymes in mammalian melanocytes. 1. Biochemical characterization of two melanosomal tyrosinases from B16 mouse melanoma.

F. Solano, J. García-Borrón, J. Lozano, 1993, European journal of biochemistry.

The melanogenic system of Xenopus laevis.

J. García-Borrón, A. Zuasti, C. Ferrer, 1998, Archives of histology and cytology.

Molecular cloning and biochemical characterization of the skin tyrosinase from Rana esculenta L.

J. García-Borrón, M. Arciuli, R. Cicero, 2009, Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology.

Tyrosinase isoenzymes: two melanosomal tyrosinases with different kinetic properties and susceptibility to inhibition by calcium.

F. Solano, J. García-Borrón, J. Lozano, 1994, Pigment cell research.

Comparison of TRPs from murine and human malignant melanocytes.

G. Ghanem, V. del Marmol, F. Solano, 1997, Pigment cell research.

Transforming Growth Factor-β1 Inhibits Basal Melanogenesis in B16/F10 Mouse Melanoma Cells by Increasing the Rate of Degradation of Tyrosinase and Tyrosinase-related Protein-1*

F. Beermann, J. García-Borrón, M. Martínez-Esparza, 1997, The Journal of Biological Chemistry.

Antimelanoma effect of 4-S-cysteaminylcatechol, an activated form of 4-S-cysteaminylphenol.

K. Wakamatsu, S. Ito, F. Solano, 1995, Cancer research.

MC1R signaling. Intracellular partners and pathophysiological implications.

J. García-Borrón, Cecilia Herraiz, C. Olivares, 2017, Biochimica et biophysica acta. Molecular basis of disease.

MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation

Z. Abdel‐Malek, J. García-Borrón, C. Jiménez‐Cervantes, 2014, Pigment cell & melanoma research.

Differential and competitive regulation of human melanocortin 1 receptor signaling by &bgr;-arrestin isoforms

J. García-Borrón, Cecilia Herraiz, C. Olivares, 2013, Journal of Cell Science.

Signaling from the human melanocortin 1 receptor to ERK1 and ERK2 mitogen-activated protein kinases involves transactivation of cKIT.

Z. Abdel‐Malek, G. Ghanem, F. Journé, 2011, Molecular endocrinology.

Mahogunin Ring Finger-1 (MGRN1) E3 Ubiquitin Ligase Inhibits Signaling from Melanocortin Receptor by Competition with Gαs*

A. B. Pérez-Oliva, J. García-Borrón, C. Olivares, 2009, The Journal of Biological Chemistry.

Melanocortin-1 receptor structure and functional regulation.

J. García-Borrón, B. Sanchez-Laorden, C. Jiménez‐Cervantes, 2005, Pigment cell research.

Regulation of the murine silver locus product (gp87) by the hypopigmenting cytokines TGF-beta1 and TNF-alpha.

F. Solano, J. García-Borrón, M. Martínez-Esparza, 2000, Pigment cell research.

Functional interplay between secreted ligands and receptors in melanoma.

J. García-Borrón, Cecilia Herraiz, B. Sanchez-Laorden, 2017, Seminars in cell & developmental biology.

Mahogunin Ring Finger 1 regulates pigmentation by controlling the pH of melanosomes in melanocytes and melanoma cells

G. Raposo, D. Bennett, E. Sviderskaya, 2021, Cellular and Molecular Life Sciences.

Antimelanoma Effect of 4S-Cysteaminylcatechol , an Activated Form of 4-5-Cysteaminylphenol 1

Hasegawa, Shigeki, Ozeki, 2006 .

Mahogunin Ring Finger 1 Is Required for Genomic Stability and Modulates the Malignant Phenotype of Melanoma Cells

D. Bennett, J. García-Borrón, Cecilia Herraiz, 2020, Cancers.

New insights on the structure of the mouse silver locus and on the function of the silver protein.

F. Solano, J. García-Borrón, M. Martínez-Esparza, 2000, Pigment cell research.

cAMP-independent non-pigmentary actions of variant melanocortin 1 receptor: AKT-mediated activation of protective responses to oxidative DNA damage

J. García-Borrón, C. Jiménez-Cervantes, Cecilia Herraiz, 2018, Oncogene.

Identification and functional analysis of novel variants of the human melanocortin 1 receptor found in melanoma patients

J. Benítez, G. Ribas, J. García-Borrón, 2009, Human mutation.

Loss-of-function variants of the human melanocortin-1 receptor gene in melanoma cells define structural determinants of receptor function.

J. Haycock, G. Ghanem, J. García-Borrón, 2002, European journal of biochemistry.

Thr40 and Met122 are new partial loss‐of‐function natural mutations of the human melanocortin 1 receptor

S. Germer, Joaquín Sánchez, J. García-Borrón, 2001, FEBS letters.

Rate limiting factors in melanocortin 1 receptor signalling through the cAMP pathway.

J. García-Borrón, C. Hahmann, Ineke Gerritsen, 2003, Pigment cell research.

MGRN1 as a Phenotypic Determinant of Human Melanoma Cells and a Potential Biomarker

S. Alonso, M. Boyano, J. García-Borrón, 2022, Life.

Mouse Ornithine Decarboxylase-like Gene Encodes an Antizyme Inhibitor Devoid of Ornithine and Arginine Decarboxylating Activity*

C. Jiménez‐Cervantes, R. Peñafiel, A. Cremades, 2006, Journal of Biological Chemistry.

MC1R is a potent regulator of PTEN after UV exposure in melanocytes.

K. Dutton-Regester, N. Hayward, Wenyi Wei, 2013, Molecular cell.

Functional Characterization of MC1R-TUBB3 Intergenic Splice Variants of the Human Melanocortin 1 Receptor

J. García-Borrón, Cecilia Herraiz, María Castejón-Griñán, 2015, PloS one.

Functional status and relationships of melanocortin 1 receptor signaling to the cAMP and extracellular signal-regulated protein kinases 1 and 2 pathways in human melanoma cells.

G. Ghanem, F. Journé, J. García-Borrón, 2012, The international journal of biochemistry & cell biology.

The melanocortin-1 receptor carboxyl terminal pentapeptide is essential for MC1R function and expression on the cell surface

L. Guillo, J. García-Borrón, J. Sánchez-Más, 2005, Peptides.

Identification and functional characterization of natural human melanocortin 1 receptor mutant alleles in Pakistani population

S. Riazuddin, Z. Ahmed, N. Sobreira, 2015, Pigment cell & melanoma research.

Activation by thyroid stimulating hormone of nerve growth factor-induced gene-B expression in thyrocytes in culture: relation with proliferation and specific gene expression.

J. Dumont, C. Maenhaut, B. Pichon, 1998, Biochimica et biophysica acta.

Induction of nerve growth factor-induced gene-B (NGFI-B) as an early event in the cyclic adenosine monophosphate response of dog thyrocytes in primary culture.

I. Pirson, C. Maenhaut, B. Pichon, 1996, Endocrinology.

Hamster zona pellucida is formed by four glycoproteins: ZP1, ZP2, ZP3, and ZP4.

J. Ballesta, M. Avilés, A. B. Pérez-Oliva, 2009, Journal of Proteome Research.

MC1R, the cAMP pathway, and the response to solar UV: extending the horizon beyond pigmentation

Z. Abdel‐Malek, J. García-Borrón, C. Jiménez‐Cervantes, 2014, Pigment cell & melanoma research.

A Side-by-Side Comparison of Wildtype and Variant Melanocortin 1 Receptor Signaling with Emphasis on Protection against Oxidative Damage to DNA

J. García-Borrón, Cecilia Herraiz, C. Olivares, 2023, International journal of molecular sciences.

Transforming growth factor-beta1 inhibits basal melanogenesis in B16/F10 mouse melanoma cells by increasing the rate of degradation of tyrosinase and tyrosinase-related protein-1.

J. García-Borrón, C. Jiménez‐Cervantes, J. A. Lozano, 1997, The Journal of biological chemistry.

MC1R signaling. Intracellular partners and pathophysiological implications.

J. García-Borrón, Cecilia Herraiz, C. Olivares, 2017, Biochimica et biophysica acta. Molecular basis of disease.

Functional interplay between secreted ligands and receptors in melanoma.

J. García-Borrón, Cecilia Herraiz, B. Sanchez-Laorden, 2017, Seminars in cell & developmental biology.

Melanoma-associated melanocortin 1 receptor variants confer redox signaling-dependent protection against oxidative DNA damage

J. García-Borrón, C. Jiménez‐Cervantes, A. Lambertos, 2024, Redox biology.