N. Suman-Chauhan

发表

Inhibition of neuronal Ca2+ influx by gabapentin and pregabalin in the human neocortex

H. Clusmann, K. Fink, Sandra Duffy, 2002, Neuropharmacology.

Expression and characterisation of human and rat CRF2α receptors

P. Carnell, R. Mackenzie, R. Franks, 1999 .

Design and synthesis of novel nonpeptide CCK-B receptor antagonists

B. K. Trivedi, R. Pinnock, J. Padia, 1997 .

PD 165929 — the first high affinity non-peptide neuromedin-B (NMB) receptor selective antagonist

R. Jordan, R. A. Lewthwaite, A. McKnight, 1996 .

Use of a dipeptide chemical library in the development of non-peptide tachykinin NK3 receptor selective antagonists.

R. A. Lewthwaite, G. Woodruff, A. McKnight, 1996, Journal of medicinal chemistry.

Two classes of structurally different antagonists display similar species preference for the human tachykinin neurokinin3 receptor.

C. Humblet, L. H. Wu, J. Bikker, 1995, Molecular pharmacology.

[3H]PD 140376: a novel and highly selective antagonist radioligand for the cholecystokininB/gastrin receptor in guinea pig cerebral cortex and gastric mucosa.

G. Woodruff, V. Dissanayake, J. C. Hunter, 1993, Molecular pharmacology.

The influence of guanyl nucleotide on agonist and antagonist affinity at guinea-pig CCK-B/gastrin receptors: Binding studies using [3H]PD140376

J. Hunter, G. Woodruff, K. Meecham, 1996, Regulatory Peptides.

Characterisation of [125I][MePhe7]neurokinin B binding to tachykinin NK3 receptors: evidence for interspecies variance.

S. Guard, G. Woodruff, Z. Madden, 1994, European journal of pharmacology.

Potent and stereospecific anticonvulsant activity of 3-isobutyl GABA relates to in vitro binding at a novel site labeled by tritiated gabapentin

C. Bigge, C. Taylor, M. Vartanian, 1993, Epilepsy Research.

The interleukin-1 type I receptor is expressed in human hypothalamus.

D. Smart, J. Hughes, S. Toulmond, 1999, Brain : a journal of neurology.

Characterization of tachykinin mediated increases in [Ca2+]i in Chinese hamster ovary cells expressing human tachykinin NK3 receptors.

G. Woodruff, Z. Madden, D. Hill, 1994, European journal of pharmacology.

The cholecystokinin-induced increase in intracellular calcium in AR42J cells is mediated by CCKB receptors linked to internal calcium stores

G. Woodruff, D. Hill, R. Pinnock, 1994, Neuropeptides.

PD 176252--the first high affinity non-peptide gastrin-releasing peptide (BB2) receptor antagonist.

R. A. Lewthwaite, A. McKnight, D. Horwell, 1998, Bioorganic & medicinal chemistry letters.

Second generation "peptoid" CCK-B receptor antagonists: identification and development of N-(adamantyloxycarbonyl)-alpha-methyl-(R)-tryptophan derivative (CI-1015) with an improved pharmacokinetic profile.

S. Rose, M. J. Field, B. K. Trivedi, 1998, Journal of medicinal chemistry.

Design and biological evaluation of non-peptide analogues of omega-conotoxin MVIIA.

J. Bikker, D. Horwell, J A Bikker, 2000, Bioorganic & medicinal chemistry letters.

Novel nonpeptide CCK-B antagonists: design and development of quinazolinone derivatives as potent, selective, and orally active CCK-B antagonists.

B. Roth, K. Meecham, M. Field, 1998, Journal of medicinal chemistry.

The development of a novel series of non-peptide tachykinin NK3 receptor selective antagonists

D. Horwell, P. Boden, M. Pritchard, 1995 .

Identification of Novel Ligands for the Gabapentin Binding Site on the α2δ Subunit of a Calcium Channel and Their Evaluation as Anticonvulsant Agents

J. Bryans, V. U. Dissanayake, N. Gee, 1998 .

Involvement of the central tachykinin NK1 receptor during maintenance of mechanical hypersensitivity induced by diabetes in the rat.

S. McCleary, J. Hughes, M. J. Field, 1998, The Journal of pharmacology and experimental therapeutics.

Synthesis of a potent and selective non-peptide CCK-B/gastrin receptor antagonist tritiated ligand.

J. Hunter, D. Horwell, D. Hill, 1993 .

The tachykinin NK1 receptor antagonist PD 154075 blocks cisplatin-induced delayed emesis in the ferret.

R. Naylor, J. Hughes, M. J. Field, 1997, European journal of pharmacology.

Pharmacological characterization of tachykinin‐stimulated inositol phospholipid hydrolysis in peripheral tissues

S. Guard, N. Suman-Chauhan, B. Williams, 1990, British journal of pharmacology.

Effects of tachykinins on inositol phospholipid hydrolysis in slices of hamster urinary bladder

N. Curtis, N. Suman-Chauhan, D. Bristow, 1987, British journal of pharmacology.

Cholecystokinin dipeptoid antagonists: design, synthesis, and anxiolytic profile of some novel CCK-A and CCK-B selective and "mixed" CCK-A/CCK-B antagonists.

D. Rees, G. Woodruff, D. Horwell, 1993, Journal of medicinal chemistry.

Localization of [3H]gabapentin to a novel site in rat brain: autoradiographic studies.

G. Woodruff, D. Hill, N. Suman-Chauhan, 1993, European journal of pharmacology.

Tachykinin-Induced Phosphatidylinositol Turnover in Hamster Urinary Bladder

K. Watling, N. Suman-Chauhan, D. Bristow, 1987 .

Characterisation of [3H]gabapentin binding to a novel site in rat brain: homogenate binding studies.

G. Woodruff, D. Hill, N. Suman-Chauhan, 1993, European journal of pharmacology.

SAR Study of the Indole Moiety of CI-988, a Potent and Selective CCK-B Antagonist

B. Tait, B. Roth, M. Wilson, 1997 .

Cholecystokinin B antagonists. Synthesis and quantitative structure-activity relationships of a series of C-terminal analogues of CI-988.

B K Trivedi, D. Ortwine, B. Roth, 1996, Bioorganic & medicinal chemistry.

Identification of novel ligands for the gabapentin binding site on the alpha2delta subunit of a calcium channel and their evaluation as anticonvulsant agents.

J. Bryans, V. U. Dissanayake, N. Gee, 1998, Journal of medicinal chemistry.

Activation of postsynaptic striatal dopamine receptors, monitored by efflux of cAMP in vivo

P. Hutson, N. Suman-Chauhan, 1990, Neuropharmacology.

Alanine scan and N-methyl amide derivatives of Ac-bombesin[7-14]. Development of a proposed binding conformation at the neuromedin B (NMB) and gastrin releasing peptide (GRP) receptors.

S. Osborne, D. Horwell, W. Howson, 2009, International journal of peptide and protein research.

The rational development of small molecule tachykinin NK3 receptor selective antagonists - the utilisation of a dipeptide chemical library in drug design

G. Woodruff, A. McKnight, K. Meecham, 1994 .

Activation of the cloned human NK3 receptor in Chinese Hamster Ovary cells characterized by the cellular acidification response using the Cytosensor microphysiometer

R. Jordan, D. Smart, A. McKnight, 1998, British journal of pharmacology.

The Rational Development of Small Molecule Tachykinin NK3 Receptor Selective Antagonists ‐ The Utilization of a Dipeptide Chemical Library in Drug Design.

G. Woodruff, A. McKnight, K. Meecham, 1995 .

In vitro and in vivo inhibition of prolyl endopeptidase.

J. Atack, J. Kulagowski, G. Dawson, 1991, European journal of pharmacology.

Conformationally restricted analogues of the potent CCK-B antagonist CI-988.

D. Horwell, D. Hill, E. Roberts, 1993, Bioorganic & medicinal chemistry.

PD 165929 - The First High Affinity Non-Peptide Neuromedin-B (NMB) Receptor Selective Antagonist.

R. Jordan, R. A. Lewthwaite, A. McKnight, 1997 .

Carboxylate bioisosteres of gabapentin.

A. El‐Kattan, S. Osborne, J. Bryans, 2006, Bioorganic & medicinal chemistry letters.