R. Cacciaglia

发表

Sodium oxybate for the maintenance of abstinence in alcohol-dependent patients: An international, multicenter, randomized, double-blind, placebo-controlled trial

W. van den Brink, D. Nutt, J. Rehm, 2022, Journal of psychopharmacology.

A Phase I randomized clinical trial testing the safety, tolerability and preliminary pharmacokinetics of the mGluR5 negative allosteric modulator GET 73 following single and repeated doses in healthy volunteers☆

L. Leggio, Kimberly Goodyear, R. Swift, 2017, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

An inpatient human laboratory study assessing the safety and tolerability, pharmacokinetics, and biobehavioral effect of GET 73 when co-administered with alcohol in individuals with alcohol use disorder

M. Magill, L. Leggio, R. Swift, 2021, Psychopharmacology.

GET73 Prevents Ethanol-Induced Neurotoxicity in Primary Cultures of Rat Hippocampal Neurons.

L. Ferraro, S. Tanganelli, S. Beggiato, 2016, Alcohol and alcoholism.

Administration of the metabotropic glutamate receptor subtype 5 allosteric modulator GET 73 with alcohol: A translational study in rats and humans

L. Leggio, Kimberly Goodyear, G. Colombo, 2018, Journal of psychopharmacology.

In Vitro Functional Characterization of GET73 as Possible Negative Allosteric Modulator of Metabotropic Glutamate Receptor 5

L. Ferraro, S. Beggiato, M. C. Tomasini, 2018, Front. Pharmacol..

SODIUMOXYBATE IN THE PREVENTION OFALCOHOL RELAPSES IN ALCOHOL DEPENDENT PATIENTS (GATE 2 STUDY)

A. Patat, G. Addolorato, J. Horodnicki, 2013 .

Dataset for Phase I randomized clinical trial for safety and tolerability of GET 73 in single and repeated ascending doses including preliminary pharmacokinetic parameters

L. Leggio, Kimberly Goodyear, R. Swift, 2017, Data in brief.

GET73 increases rat extracellular hippocampal CA1 GABA levels through a possible involvement of local mGlu5 receptor

L. Ferraro, S. Tanganelli, S. Beggiato, 2013, Synapse.

The new compound GET73, N-[(4-trifluoromethyl)benzyl]4-methoxybutyramide, Regulates hippocampal Aminoacidergic transmission possibly via an allosteric modulation of mGlu5 receptor. Behavioural evidence of its "anti-alcohol" and anxiolytic properties.

L. Ferraro, S. Tanganelli, S. Beggiato, 2013, Current medicinal chemistry.

Anti-Alcohol and Anxiolytic Properties of a New Chemical Entity, GET73

G. Colombo, M. P. Castelli, D. Barone, 2012, Front. Psychiatry.

GET 73 Prevents Ethanol-Induced Neurotoxicity in Primary Cultures of Rat Hippocampal Neurons

L. Ferraro, S. Tanganelli, S. Beggiato, 2016 .

GET73 modulates lipopolysaccharide- and ethanol-induced increase in cytokine/chemokine levels in primary cultures of microglia of rat cerebral cortex.

S. Beggiato, M. C. Tomasini, A. Loche, 2024, Pharmacological reports : PR.