Zhaopeng Liu

发表

A Unique GSK-3β inhibitor B10 Has a Direct Effect on Aβ, Targets Tau and Metal Dyshomeostasis, and Promotes Neuronal Neurite Outgrowth

N. Yan, Ying-jie Cui, Xiao-Long Shi, 2020, Cells.

Synthesis and biological evaluation of thieno[3,2-c]pyrazol-3-amine derivatives as potent glycogen synthase kinase 3β inhibitors for Alzheimer’s disease

N. Yan, Chao Liu, Long-Qian Tang, 2022, Journal of enzyme inhibition and medicinal chemistry.

SAR Investigation and Discovery of Water-Soluble 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazoles as Potent Tubulin Polymerization Inhibitors.

Cheng-Mei Zhang, Jing-De Wu, Chao Liu, 2020, Journal of medicinal chemistry.

The discovery of novel indazole derivatives as tubulin colchicine site binding agents that displayed potent antitumor activity both in vitro and in vivo.

Cheng-Mei Zhang, Chen-Chen Ma, Long-Qian Tang, 2019, European journal of medicinal chemistry.

Synthesis and Evaluation of Novel 2H-Benzo[e]-[1,2,4]thiadiazine 1,1-Dioxide Derivatives as PI3Kδ Inhibitors

Long-Qian Tang, Zhaopeng Liu, Ya-Ping Gong, 2019, Molecules.

Synthesis and biological evaluation of selective histone deacetylase 6 inhibitors as multifunctional agents against Alzheimer's disease.

Cong-Cong Jia, N. Yan, Xiujiao Wang, 2021, European journal of medicinal chemistry.

Synthesis and antibacterial activity of novel 3-O-carbamoyl derivatives of clarithromycin and 11,12-cyclic carbonate azithromycin.

L. Song, Zerong Li, Hui Li, 2010, European journal of medicinal chemistry.

Synthesis and antibacterial activity of novel 11,12-cyclic carbonate azithromycin 4″-O-carbamate derivatives

Shutao Ma, Hualong Song, Chenchen Ma, 2010, The Journal of Antibiotics.

Synthesis and antibacterial activity of novel 15-membered macrolide derivatives: 4''-carbamate, 11,12-cyclic carbonate-4''-carbamate and 11,4''-di-O-arylcarbamoyl analogs of azithromycin.

Shutao Ma, Ruixin Ma, Xuecui Shen, 2009, European journal of medicinal chemistry.

Synthesis and antibacterial activity of 4'',11-di-O-arylalkylcarbamoyl azithromycin derivatives.

H. Lou, H. Wang, Shutao Ma, 2009, Bioorganic & medicinal chemistry letters.

Stereoselective reduction of C-20 ketone of vitamin D CD-ring and a new synthetic approach to maxacalcitol

Guo-Dong Zhao, Zhaopeng Liu, 2014, Steroids.

Preparation of S14161 and its analogues and the discovery of 6-bromo-8-ethoxy-3-nitro-2H-chromene as a more potent antitumor agent in vitro.

X. Mao, B. Cao, Xiaoling Du, 2013, Bioorganic & medicinal chemistry letters.

Developments of kinesin spindle protein inhibitors as antitumor agents based on the five-membered heterocycle scaffolds.

Guo-Dong Zhao, Ren-zhong Wan, Zhaopeng Liu, 2014, Current medicinal chemistry.

Recent Research Advances in Selective Matrix Metalloproteinase‐13 Inhibitors as Anti‐Osteoarthritis Agents

Ren-zhong Wan, Zhaopeng Liu, Xin-Wen Xie, 2017, ChemMedChem.

Synthesis and structure–activity relationships studies of brartemicin analogs as anti-invasive agents

I. Saiki, Y. Igarashi, Xiu-zhen Han, 2013, The Journal of Antibiotics.

Synthesis and evaluation of trehalose-based compounds as anti-invasive agents.

I. Saiki, Y. Igarashi, S. Miyanaga, 2011, Bioorganic & medicinal chemistry letters.

Therapeutic Potential of a Novel Vitamin D3 Oxime Analogue, VD1-6, with CYP24A1 Enzyme Inhibitory Activity and Negligible Vitamin D Receptor Binding

M. Wiese, M. Sykes, Dongqing Yang, 2022, Biomolecules.

IODOTRIMETHYLSILANE AND CATALYTIC IODINE PROMOTED CYCLIZATION FOR THE FACILE SYNTHESIS OF 3-MONOARYLATED FIVE-MEMBERED BENZOSULTAMS

Shutao Ma, Yue-Hui Dong, Zhaopeng Liu, 2010 .

Identification of a promising PI3K inhibitor for the treatment of multiple myeloma through the structural optimization

X. Mao, B. Cao, Jingyu Zhu, 2014, Journal of Hematology & Oncology.

Design, synthesis and tumor cell growth inhibitory activity of 3-nitro-2H-cheromene derivatives as histone deacetylaes inhibitors.

Jingde Wu, Shuai Tan, Ting Kong, 2017, Bioorganic & medicinal chemistry.

Developments of DNA-dependent Protein Kinase Inhibitors as Anticancer Agents.

Hui Li, Chen-Chen Ma, Ren-zhong Wan, 2014, Mini reviews in medicinal chemistry.

Structural revisions of the reported A-ring phosphine oxide synthon for ED-71 (Eldecalcitol) and a new synthesis

Guo-Dong Zhao, Zhaopeng Liu, 2015 .

Expeditious Synthesis of 3, 4-Dihydro-2H-1λ6-benzo[e][1, 2]thiazine 1, 1-Dioxides

Y. Takéuchi, N. Shibata, A. Satoh, 1999 .

N-Fluoro-3-ethyl-3-methyl-1,1-dioxo-2,3-dihydro-1H-1λ6-benzo[e]1,2-thiazin-4-one, a new and efficient agent for electrophilic fluorination of carbanions

Y. Takéuchi, K. Kirk, N. Shibata, 1999 .

Facile synthesis of disubstituted and spiro five-membered benzosultams mediated by TMSCl–NaI–MeCN reagent

Y. Takéuchi, N. Shibata, Zhaopeng Liu, 2002 .

Synthesis of novel chiral fluorinating agents, (+)- and (−)-N-fluoro-3-methyl-3-(4-methylphenyl)-2H-benzo[e][1,2]thiazine-1,1,4-triones

Huiliang Sun, Long-Qian Tang, Zhaopeng Liu, 2008 .

Discovery of lysosome-targeted covalent anticancer agents based on isosteviol skeleton.

A. Ji, H. Lou, Lin Li, 2020, European journal of medicinal chemistry.

Synthesis of Sulfonylhydrazone‐ and Acylhydrazone‐Substituted 8‐Ethoxy‐3‐nitro‐2H‐chromenes as Potent Antiproliferative and Apoptosis Inducing Agents

Yuntong Ma, Datong Zhang, Y. Liu, 2014, Archiv der Pharmazie.

Evaluation of WO2017018805: 1,3,4-oxadiazole sulfamide derivatives as selective HDAC6 inhibitors

Zhao-Peng Liu, Yuan-Yuan Liang, Cheng-Mei Zhang, 2018, Expert opinion on therapeutic patents.

New developments in the synthesis of saccharin related five- and six-membered benzosultams

Y. Takéuchi, Zhaopeng Liu, 2009 .

A Novel Synthetic Approach to Benzo[d]isothiazole 1,1‐Diones Having a Secondary Alkyl Substituent at the 3‐Position

Y. Takéuchi, Zhaopeng Liu, Tetsuya Toyoshi, 2004 .

Visible-light-mediated de-aminative alkylation of N-arylamines with alkyl Katritzky salts

Zhao-Peng Liu, H. Lou, Ze‐Jun Xu, 2019, Organic Chemistry Frontiers.

Design and Synthesis of Coumarin Derivatives as Novel PI3K Inhibitors.

Chen-Chen Ma, Zhaopeng Liu, 2017, Anti-cancer agents in medicinal chemistry.

Design, synthesis, and biological evaluation of 3-(1-benzotriazole)-nor-β-lapachones as NQO1-directed antitumor agents.

Liqiang Wu, Xin Ma, Zhaopeng Liu, 2021, Bioorganic chemistry.

Synthesis of Novel Pyrazole Derivatives and Their Tumor Cell Growth Inhibitory Activity

Cheng-Mei Zhang, Long-Qian Tang, Ying-jie Cui, 2019, Molecules.

Substrate- and Reagent-Controlled Electrophilic Asymmetric Fluorinations

Shutao Ma, B. Gao, Zhaopeng Liu, 2010 .

Benzosultams: Synthesis and Applications

Y. Takéuchi, Zhaopeng Liu, 2002 .

Tubulin Maytansine Site Binding Ligands and Their Applications as MTAs and ADCs for Cancer Therapy.

Shuo Cao, Yue-Hui Dong, Zhaopeng Liu, 2020, Current medicinal chemistry.

Design, synthesis, bioevaluation of LFC- and PA-tethered anthraquinone analogues of mitoxantrone.

Xun Li, Zhaopeng Liu, Xin-Wen Xie, 2020, Bioorganic chemistry.

An efficient synthesis of (R)- and (S)-8-ethoxy-2-(4-fluorophenyl)-3-nitro-2H-chromene

X. Mao, Can-Fei Zhang, Zhaopeng Liu, 2013 .

Natural Products as Zinc‐Dependent Histone Deacetylase Inhibitors

Shuai Tan, Zhaopeng Liu, 2015, ChemMedChem.

Design, Synthesis, and Biological Evaluation of 1-Methyl-1,4-dihydroindeno[1,2-c]pyrazole Analogues as Potential Anticancer Agents Targeting Tubulin Colchicine Binding Site.

Cheng-Mei Zhang, Long-Qian Tang, Guo-Dong Zhao, 2016, Journal of medicinal chemistry.

Synthesis and Evaluation of Trehalose‐Based Compounds as Novel Inhibitors of Cancer Cell Migration and Invasion

Xiu-zhen Han, L. Ge, Zhaopeng Liu, 2015, Chemical biology & drug design.

Recent developments of small molecule PI3K/mTOR dual inhibitors.

Ren-zhong Wan, Zhaopeng Liu, Yan-Na Liu, 2013, Mini reviews in medicinal chemistry.

Discovery of novel quinazolinone derivatives as high potent and selective PI3Kδ and PI3Kδ/γ inhibitors.

Zhao-Peng Liu, Cheng-Mei Zhang, Chen-Chen Ma, 2018, European journal of medicinal chemistry.

Tubulin colchicine binding site inhibitors as vascular disrupting agents in clinical developments.

Zhaopeng Liu, Ya-Ting Ji, Yan-Na Liu, 2015, Current medicinal chemistry.

Recent developments of p38α MAP kinase inhibitors as antiinflammatory agents based on the imidazole scaffolds.

Cheng-Mei Zhang, Ting Kong, Zhaopeng Liu, 2013, Current medicinal chemistry.

Synthetic studies towards 1α-hydroxysolasodine from diosgenin and the unexpected tetrahydrofuran ring opening in the Birch reduction process

H. Lou, Chao Liu, Guo-Dong Zhao, 2015, Steroids.

Design, synthesis, and biological evaluation of 4-substituted-3,4-dihydrobenzo[h]quinoline-2,5,6(1H)-triones as NQO1-directed antitumor agents.

Liqiang Wu, Chong Zhang, Xin Ma, 2020, European journal of medicinal chemistry.

PCSK9 Inhibitors: Novel Therapeutic Strategies for Lowering LDLCholesterol.

Yan Wang, Yan Wang, Zhao-Peng Liu, 2018, Mini reviews in medicinal chemistry.

DHPAC, a novel synthetic microtubule destabilizing agent, possess high anti-tumor activity in vincristine-resistant oral epidermoid carcinoma in vitro and in vivo.

Zhen-Ning Lu, Ying Zhang, Yan-na Cheng, 2017, The international journal of biochemistry & cell biology.

Recent Developments of C-Aryl Glucoside SGLT2 Inhibitors.

Zhao-Peng Liu, Yang Zhang, Zhaopeng Liu, 2016, Current medicinal chemistry.

A branched small molecule-drug conjugate nanomedicine strategy for the targeted HCC chemotherapy.

Zhao-Peng Liu, Cheng-Mei Zhang, Sha-Sha Li, 2021, European journal of medicinal chemistry.

Recent advances in the discovery of potent and selective HDAC6 inhibitors.

Xiujiao Wang, Ren-zhong Wan, Zhaopeng Liu, 2018, European journal of medicinal chemistry.

Evaluation of WO2017098421: GSK’s benzothiazine compounds as CD73 inhibitor filings

Ren-zhong Wan, Zhaopeng Liu, Ya-Ping Gong, 2018, Expert opinion on therapeutic patents.

Recent developments of RET protein kinase inhibitors with diverse scaffolds as hinge binders.

Cong-Cong Jia, Wang Chen, Zili Feng, 2020, Future medicinal chemistry.

Tubulin colchicine site binding agent LL01 displays potent antitumor efficiency both in vitro and in vivo with suitable drug-like properties

Zhao-Peng Liu, Cheng-Mei Zhang, Jing-De Wu, 2019, Investigational New Drugs.

Synthesis and evaluation of novel GSK-3β inhibitors as multifunctional agents against Alzheimer's disease.

Jing-De Wu, Ping Liu, Xiao-Long Shi, 2019, European journal of medicinal chemistry.

Synthesis and biological evaluation of 1α,25-dihydroxyvitamin D3 analogues with aromatic side chains attached at C-17.

X. Mao, Zhao-Peng Liu, Cheng-Mei Zhang, 2014, European journal of medicinal chemistry.

Recent Developments of 19‐Nor‐1,25‐dihydroxyvitamin D3 Analogues

Zhao-Peng Liu, Can-Fei Zhang, Ren-zhong Wan, 2013, ChemMedChem.

Design and synthesis of highly potent HIV-1 protease inhibitors with novel isosorbide-derived P2 ligands.

Guo-Dong Zhao, X. Qiu, Zhaopeng Liu, 2014, Bioorganic & medicinal chemistry letters.

Design and synthesis of potent HIV-1 protease inhibitors incorporating hydroxyprolinamides as novel P2 ligands.

Cheng-Mei Zhang, B. Gao, Long-Qian Tang, 2011, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of thieno[3,2-c]pyrazol-3-amine derivatives as potent glycogen synthase kinase 3β inhibitors for Alzheimer's disease.

N. Yan, Chao Liu, Long-Qian Tang, 2023, Bioorganic chemistry.

Synthesis and biological evaluation of BU-4664L derivatives as potential anticancer agents.

Zhao-Peng Liu, Chao Liu, Yuan-yuan Xu, 2021, Bioorganic & medicinal chemistry letters.

Recent developments of 2-substituted analogs of 1,25(OH)(2)D(3).

Can-Fei Zhang, Zhaopeng Liu, 2013, Current Medicinal Chemistry.

Synthesis of 1α,25-dihydroxyvitamin D3 analogues with α,α-difluorocycloketone at the CD-ring side chains and their biological properties in ovariectomized rats

W. Wang, Guo-Dong Zhao, Ying-jie Cui, 2019, The Journal of Steroid Biochemistry and Molecular Biology.

Histochemical evidence of IGF2 mRNA-binding protein 2-mediated regulation of osteoclast function and adhesive ability

Shanshan Liu, Minqi Li, Dongfang Li, 2018, Histochemistry and Cell Biology.

A novel PI3K inhibitor displays potent preclinical activity against an androgen-independent and PTEN-deficient prostate cancer model established from the cell line PC3.

X. Mao, B. Cao, Zhao-Peng Liu, 2014, Toxicology letters.

Synthesis of Novel Nucleoside Analogues Based on 1,3‐Dihydrobenzo[c]furan Core

Zhaopeng Liu, Delou Wang, Zhao‐Li Meng, 2006 .

Recoverable Pd/C catalyst mediated dehydrogenation of sterols and an improved synthesis of 1α-hydroxydehydroepiandrosterone

Chao Liu, Long-Qian Tang, Zhaopeng Liu, 2012, Steroids.

Recent developments of small molecule EGFR inhibitors based on the quinazoline core scaffolds.

Cheng-Mei Zhang, Zhaopeng Liu, Yu-Jing Yu-Jing, 2012, Anti-cancer agents in medicinal chemistry.

Synthesis and anti-SARS-CoV-2 evaluation of lipid prodrugs of β-D-N4-hydroxycytidine (NHC) and a 3′-fluoro-substituted analogue of NHC

P. Herdewijn, G. Andrei, R. Snoeck, 2023, Bioorganic Chemistry.

Recent Advances in the Development of Casein Kinase 1 Inhibitors.

Sha-Sha Li, Yue-Hui Dong, Zhaopeng Liu, 2020, Current medicinal chemistry.

Tumor selective self-assembled nanomicelles of carbohydrate-epothilone B conjugate for targeted chemotherapy.

Zhiyue Zhang, Ze‐Jun Xu, Lilin Qian, 2023, European journal of medicinal chemistry.

DHPAC, a novel synthetic microtubule destabilizing agent, possess high anti-tumor activity in vincristine-resistant oral epidermoid carcinoma in vitro and in vivo.

Ying Zhang, Yan-na Cheng, Lu-Gang Yu, 2017, The international journal of biochemistry & cell biology.