Chao Wang

发表

TNF-α-inducing protein of Helicobacter pylori induces epithelial-mesenchymal transition (EMT) in gastric cancer cells through activation of IL-6/STAT3 signaling pathway.

Min-jun Yu, L. Xiao, Lanhua Zhao, 2017, Biochemical and biophysical research communications.

Y08060: A Selective BET Inhibitor for Treatment of Prostate Cancer.

Yan Zhang, Yong Xu, C. Zhang, 2018, ACS medicinal chemistry letters.

Design, synthesis, and anticancer evaluation of ammosamide B with pyrroloquinoline derivatives as novel BRD4 inhibitors.

Min Wang, Yan Zhang, Yong Xu, 2022, Bioorganic chemistry.

Structure-Based Discovery and Optimization of Furo[3,2-c]pyridin-4(5H)-one Derivatives as Potent and Second Bromodomain (BD2)-Selective Bromo and Extra Terminal Domain (BET) Inhibitors.

Yan Zhang, Yong Xu, H. Xu, 2022, Journal of medicinal chemistry.

Design, synthesis and anticancer evaluation of 3-methyl-1H-indazole derivatives as novel selective bromodomain-containing protein 4 inhibitors.

Cheng-Mei Zhang, Li‐Ping Sun, Yong-jin Xu, 2021, Bioorganic & medicinal chemistry.

Discovery, optimization and evaluation of 1-(indolin-1-yl)ethan-1-ones as novel selective TRIM24/BRPF1 bromodomain inhibitors.

Yan Zhang, Yong Xu, Qiu-ping Xiang, 2022, European journal of medicinal chemistry.

Structural insights revealed by the cocrystal structure of CCS1477 in complex with CBP bromodomain.

Yan Zhang, Qiu-ping Xiang, Yong Xu, 2022, Biochemical and biophysical research communications.

Design, synthesis and pharmacological characterization of N-(3-ethylbenzo[d]isoxazol-5-yl) sulfonamide derivatives as BRD4 inhibitors against acute myeloid leukemia

Yan Zhang, Xiao-yu Luo, Yong Xu, 2022, Acta Pharmacologica Sinica.

Discovery and optimization of novel N-benzyl-3,6-dimethylbenzo[d]isoxazol-5-amine derivatives as potent and selective TRIM24 bromodomain inhibitors with potential anti-cancer activities.

Yan Zhang, Yong Xu, Donghai Wu, 2019, Bioorganic chemistry.

Y08197 is a novel and selective CBP/EP300 bromodomain inhibitor for the treatment of prostate cancer

Yan Zhang, Yong Xu, Qiu-ping Xiang, 2019, Acta Pharmacologica Sinica.

Elimination of CD4lowHLA-G+ T cells overcomes castration-resistance in prostate cancer therapy

F. Wang, Wei-Qiang Gao, Bing Zhang, 2018, Cell Research.

Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer (CRPC).

Yan Zhang, Yong Xu, Donghai Wu, 2018, Journal of medicinal chemistry.

Discovery and Characterization of XY101, a Potent, Selective, and Orally Bioavailable RORγ Inverse Agonist for Treatment of Castration-Resistant Prostate Cancer.

Yan Zhang, Yong Xu, Donghai Wu, 2019, Journal of medicinal chemistry.

The evolving role of immune cells in prostate cancer.

Wei-Qiang Gao, Yan Zhang, Chao Wang, 2021, Cancer letters.

Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer.

Yan Zhang, Yong Xu, Guohui Li, 2018, European journal of medicinal chemistry.

CCL5-deficiency enhances intratumoral infiltration of CD8+ T cells in colorectal cancer

Wei-Qiang Gao, Shengbo Zhang, M. Zhong, 2018, Cell Death & Disease.

Design, Synthesis, and Biological Evaluation of 1-(Indolizin-3-yl)ethan-1-ones as CBP Bromodomain Inhibitors for the Treatment of Prostate Cancer.

Yan Zhang, Yong Xu, X. Kong, 2021, Journal of medicinal chemistry.

Y06014 is a selective BET inhibitor for the treatment of prostate cancer

Yan Zhang, Yong Xu, Qiu-ping Xiang, 2021, Acta Pharmacologica Sinica.

CCL5-deficiency enhances intratumoral infiltration of CD8+ T cells in colorectal cancer

Wei-Qiang Gao, Shengbo Zhang, M. Zhong, 2018, Cell Death & Disease.

Discovery and optimization of 1-(1H-indol-1-yl)ethanone derivatives as CBP/EP300 bromodomain inhibitors for the treatment of castration-resistant prostate cancer.

Cheng Zhang, Ke Ding, Donghai Wu, 2018, European journal of medicinal chemistry.

Characteristics of changes in the functional status of the brain before and after 1,000 m all-out paddling for different levels of dragon boat athletes

Hongke Jiang, Yingying Cao, Qianqian Wu, 2023, Frontiers in Psychology.

Discovery and Characterization of Benzimidazole Derivative XY123 as a Potent, Selective, and Orally Available RORγ Inverse Agonist.

Yan Zhang, Yong Xu, Donghai Wu, 2021, Journal of medicinal chemistry.

Discovery and Optimization of Selective Inhibitors of Meprin α (Part I)

T. Spicer, G. Fields, L. Scampavia, 2020, Pharmaceuticals.

Discovery and Optimization of Selective Inhibitors of Meprin α (Part II)

T. Spicer, G. Fields, Hajeung Park, 2020, Pharmaceuticals.

Discovery of a potent and selective CBP bromodomain inhibitor (Y08262) for treating acute myeloid leukemia

Yan Zhang, Qiu-ping Xiang, Tian Wu, 2023, Bioorganic Chemistry.

Elimination of CD4lowHLA-G+ T cells overcomes castration-resistance in prostate cancer therapy

F. Wang, Wei-Qiang Gao, Bing Zhang, 2018, Cell Research.

Y08197 is a novel and selective CBP/EP300 bromodomain inhibitor for the treatment of prostate cancer

Yan Zhang, Yong Xu, Qiu-ping Xiang, 2019, Acta Pharmacologica Sinica.