Leanna L. Lagpacan

发表

Inhibition of Hepatitis C Virus Replication by GS-6620, a Potent C-Nucleoside Monophosphate Prodrug

W. Zhong, M. Fenaux, K. Kitrinos, 2014, Antimicrobial Agents and Chemotherapy.

The characterization of idelalisib binding to PI3Kδ 1 Structural, biochemical and biophysical characterization of idelalisib binding to phosphoinositide 3-kinase delta*

J. R. Somoza, Melanie H. Wong, M. Mcgrath, 2015 .

In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy.

Susan E. Cellitti, J. Caldwell, P. Schultz, 2008, Journal of the American Chemical Society.

Inhibition of Hepatitis C Virus Replication by GS-6620 , A Potent C-Nucleoside 1 Monophosphate Prodrug 2 3 Running Title : In Vitro Pharmacology of GS-6620 4 5

W. Zhong, M. Fenaux, G. Cheng, 2014 .

Elucidating molecular interactions of L-nucleotides with HIV-1 reverse transcriptase and mechanism of M184V-caused drug resistance

Z. Suo, E. Lansdon, Lijun Zhang, 2019, Communications Biology.

Elucidating molecular interactions of L-nucleotides with HIV-1 reverse transcriptase and mechanism of M184V-caused drug resistance.

Z. Suo, E. Lansdon, Lijun Zhang, 2019 .

Visualizing the molecular interactions of a nucleotide analog, GS-9148, with HIV-1 reverse transcriptase-DNA complex.

K. White, Xiaohong Liu, M. Mcgrath, 2010, Journal of molecular biology.

Structural and Regulatory Elements of HCV NS5B Polymerase – β-Loop and C-Terminal Tail – Are Required for Activity of Allosteric Thumb Site II Inhibitors

Melanie H. Wong, S. E. Boyce, T. Appleby, 2014, PloS one.

Discovery of potent and selective inhibitors of calmodulin-dependent kinase II (CaMKII).

J. R. Somoza, Xiaofen Li, N. Pagratis, 2017, Bioorganic & medicinal chemistry letters.

Lipid-Sensing High-Throughput ApoA-I Assays

Xiaohong Liu, J. W. Chisholm, N. Pagratis, 2012, Journal of biomolecular screening.

1198 NUCLEOTIDE INHIBITOR RESISTANCE SELECTIONS USING GT2A INFECTIOUS VIRUS: PSI-7851 AND GS-6620 SELECT FOR A NOVEL RESISTANCE PATHWAY INCLUDING SUBSTITUTIONS OF M289V/L FOLLOWED BY S282T

Xiaohong Liu, W. Zhong, M. Fenaux, 2011 .

Structural, Biochemical, and Biophysical Characterization of Idelalisib Binding to Phosphoinositide 3-Kinase δ*

Latesh Lad, Mary E. McGrath, J. R. Somoza, 2015, The Journal of Biological Chemistry.

Structural, Biochemical, and Biophysical Characterization of Idelalisib Binding to Phosphoinositide 3-Kinase (cid:2) *

J. R. Somoza, Giuseppe A. Papalia, L. Lad, 2020 .