S. Bot

The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2'-α-chloro-2'-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors.

J. Bilello, S. Cappelle, I. Serra, 2017, Bioorganic & medicinal chemistry letters.

Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor.

Catherine Caillet, J. McCarville, M. Liuzzi, 2017, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of aryl-phospho-indole as novel HIV-1 non-nucleoside reverse transcriptase inhibitors.

Catherine Caillet, R. Storer, M. Liuzzi, 2011, Journal of medicinal chemistry.

Development and Scale-Up of a Manufacturing Route for the Non-nucleoside Reverse Transcriptase Inhibitor GSK2248761A (IDX-899): Synthesis of an Advanced Key Chiral Intermediate

G. Bret, Catherine Caillet, J. Hayler, 2018 .

Discovery of the Aryl-phospho-indole IDX899, a Highly Potent Anti-HIV Non-nucleoside Reverse Transcriptase Inhibitor.

Catherine Caillet, R. Storer, M. Liuzzi, 2016, Journal of medicinal chemistry.