Jean-laurent Paparin

The discovery of IDX21437: Design, synthesis and antiviral evaluation of 2'-α-chloro-2'-β-C-methyl branched uridine pronucleotides as potent liver-targeted HCV polymerase inhibitors.

J. Bilello, S. Cappelle, I. Serra, 2017, Bioorganic & medicinal chemistry letters.

Discovery of benzophosphadiazine drug candidate IDX375: A novel hepatitis C allosteric NS5B RdRp inhibitor.

Catherine Caillet, J. McCarville, M. Liuzzi, 2017, Bioorganic & medicinal chemistry letters.

Synthesis of 2,5‐bis‐arylpyridines by [4 + 2] cycloaddition of 1,4‐bis aryl‐2‐aza‐1,3‐butadienes with electron‐poor dienophiles

R. Grée, L. Toupet, C. Crévisy, 2000 .

Synthesis and Functionalization of New Tropanes Designed for Use as Scaffolds in Combinatorial Chemistry

R. Grée, L. Toupet, C. Crévisy, 2000 .

tert-Butoxycarbamate group: a useful protecting group for the synthesis of orthogonally protected ‘tropane-like’ scaffolds

R. Grée, C. Crévisy, Jean-laurent Paparin, 2000 .

Synthesis of potent and broad genotypically active NS5B HCV non-nucleoside inhibitors binding to the thumb domain allosteric site 2 of the viral polymerase.

J. McCarville, M. Liuzzi, Cyril Dousson, 2016, Bioorganic & medicinal chemistry letters.