Andrew J. Ambrose

发表

The Hybrid Pyrroloisoindolone–Dehydropyrrolizine Alkaloid (−)‐Chlorizidine A Targets Proteins within the Glycolytic Pathway

E. Chapman, W. Fenical, D. Rocha, 2015, Chembiochem : a European journal of chemical biology.

One-Step Synthesis of Thieno[2,3-d]pyrimidin-4(3H)-ones via a Catalytic Four-Component Reaction of Ketones, Ethyl Cyanoacetate, S8 and Formamide.

Donna D. Zhang, E. Chapman, Taoda Shi, 2018, ACS sustainable chemistry & engineering.

Heat shock protein Grp78/BiP/HspA5 binds directly to TDP-43 and mitigates toxicity associated with disease pathology

J. Shorter, M. Khanna, R. Khanna, 2022, Scientific Reports.

Identification of pyrazine-based TrkA inhibitors: design, synthesis, evaluation, and computational modeling studies.

Zhigang Xu, Hong‐yu Li, Yuanxiang Wang, 2014, MedChemComm.

Caspase‐6‐cleaved tau is relevant in Alzheimer's disease and marginal in four‐repeat tauopathies: Diagnostic and therapeutic implications

M. Arkin, Shireen Khan, S. Spina, 2022, Neuropathology and applied neurobiology.

Heat Shock Protein Grp78/BiP/HspA5 Binds Directly to TDP-43 and Mitigates Toxicity Associated with Neurodegenerative Disease Pathology

J. Shorter, M. Khanna, R. Khanna, 2021 .

Functional Differences between E. coli and ESKAPE Pathogen GroES/GroEL

Steven M. Johnson, E. Chapman, Q. Q. Hoang, 2021, mBio.

iPSC-induced neurons with the V337M MAPT mutation are selectively vulnerable to caspase-mediated cleavage of tau and apoptotic cell death

L. Grinberg, Celeste M. Karch, Chao Wang, 2021 .

ATP-competitive, marine derived natural products that target the DEAD box helicase, eIF4A.

J. Schatz, Donna D. Zhang, Abimael D Rodríguez, 2017, Bioorganic & medicinal chemistry letters.

Arsenic Compromises Both p97 and Proteasome Functions.

Donna D. Zhang, E. Chapman, Minjin Kang, 2017, Chemical research in toxicology.

Physachenolide C is a Potent, Selective BET Inhibitor.

N. Horton, M. Clarkson, R. Fromme, 2022, Journal of medicinal chemistry.

Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78.

Donna D. Zhang, E. Chapman, L. Lairson, 2022, Journal of medicinal chemistry.

A one-step, atom economical synthesis of thieno[2,3-d]pyrimidin-4-amine derivatives via a four-component reaction.

Donna D. Zhang, E. Chapman, Taoda Shi, 2019, European journal of organic chemistry.

Copper Chaperone CupA and Zinc Control CopY Regulation of the Pneumococcal cop Operon

M. Neubert, Michael D. L. Johnson, Andrew J. Ambrose, 2017, mSphere.

An isoform-selective PTP1B inhibitor derived from nitrogen-atom augmentation of radicicol.

B. Blagg, Donna D. Zhang, A. Gunatilaka, 2019, Biochemistry.

Sulfonamido-2-arylbenzoxazole GroEL/ES Inhibitors as Potent Antibacterials against Methicillin-Resistant Staphylococcus aureus (MRSA).

Steven M. Johnson, P. Schultz, A. Horwich, 2018, Journal of medicinal chemistry.