E. Altschuler

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The effect of staurosporine on drug-induced, topoisomerase II-mediated DNA cleavage in human leukemia cells

L. Zwelling, D. Chan, E. Altschuler, 2004, Cancer Chemotherapy and Pharmacology.

Advances in Brief Identification of a Point Mutation in the Topoisomerase II Gene from a Human Leukemia Cell Line Containing an Amsacrine-resistant Form of Topoisomerase II 1

L. Zwelling, F. Ledley, E. Altschuler, 2006 .

Phorbol regulation of topoisomerases I and II in human leukemia cells. Studies in an additional cell pair sensitive or resistant to phorbol-induced differentiation.

L. Zwelling, T. Zipf, E. Bales, 1994, Biochemical pharmacology.

Phorbol ester effects on topoisomerase II activity and gene expression in HL-60 human leukemia cells with different proclivities toward monocytoid differentiation.

L. Zwelling, D. Chan, T. Zipf, 1990, Cancer research.

Phorbol ester-induced down-regulation of topoisomerase II alpha mRNA in a human erythroleukemia cell line. Evidence for a post-transcriptional mechanism.

L. Zwelling, I. Hickson, D. Hochhauser, 1996, Biochemical pharmacology.

Proclivities toward Monocytoid Differentiation Expression in HL-60 Human Leukemia Cells with Different Phorbol Ester Effects on Topoisomerase II Activity and Gene

L. Zwelling, D. Chan, T. Zipf, 2006 .

Effect of bryostatin 1 on drug-induced, topoisomerase II-mediated DNA cleavage and topoisomerase II gene expression in human leukemia cells.

L. Zwelling, D. Chan, G. Pettit, 1991, Biochemical pharmacology.

Mechanism of action and antitumor activity of (S)-10-(2,6-dimethyl-4-pyridinyl)-9-fluoro-3-methyl-7-oxo-2,3-dihydro-7 H- pyridol[1,2,3-de]-[1,4]benzothiazine-6-carboxylic acid (WIN 58161).

L. Zwelling, T. Corbett, W. Waud, 1995, Biochemical pharmacology.

Radioprotection of cultured Chinese hamster ovary cells by WR-255591.

L. Milas, D. Murray, R. Meyn, 1988, International journal of radiation biology.

Further characterization of an amsacrine-resistant line of HL-60 human leukemia cells and its topoisomerase II. Effects of ATP concentration, anion concentration, and the three-dimensional structure of the DNA target.

L. Zwelling, E. Altschuler, J. Mayes, 1993, Biochemical pharmacology.

Identification of a point mutation in the topoisomerase II gene from a human leukemia cell line containing an amsacrine-resistant form of topoisomerase II.

K. Deisseroth, L. Zwelling, F. Ledley, 1991, Cancer research.

Cross-resistance of an amsacrine-resistant human leukemia line to topoisomerase II reactive DNA intercalating agents. Evidence for two topoisomerase II directed drug actions.

K. Deisseroth, L. Zwelling, D. Chan, 1991, Biochemistry.

Comparative effect of the thiols dithiothreitol, cysteamine and WR-151326 on survival and on the induction of DNA damage in cultured Chinese hamster ovary cells exposed to gamma-radiation.

L. Milas, D. Murray, S. C. Vanankeren, 1990, International journal of radiation biology.

Protection by WR-3689 against gamma-ray-induced intestinal damage: comparative effect on clonogenic cell survival, mouse survival, and DNA damage.

L. Milas, D. Murray, N. Hunter, 1989, Radiation research.

Relative activity of structural analogues of amsacrine against human leukemia cell lines containing amsacrine-sensitive or -resistant forms of topoisomerase II: use of computer simulations in new drug development.

L. Zwelling, B. Baguley, E. Altschuler, 1992, Cancer research.

Activity of two novel anthracene-9,10-diones against human leukemia cells containing intercalator-sensitive or -resistant forms of topoisomerase II.

L. Zwelling, M. Hacker, T. Tritton, 1993, Biochemical pharmacology.

Circumvention of resistance by doxorubicin, but not by idarubicin, in a human leukemia cell line containing an intercalator-resistant form of topoisomerase II: evidence for a non-topoisomerase II-mediated mechanism of doxorubicin cytotoxicity.

L. Zwelling, E. Bales, E. Altschuler, 1993, Biochemical pharmacology.

Advances in Brief W-^ S-DiacetoxypentyOdoxorubicin : A Novel Anthracycline Producing DNA Interstrand Cross-Linking and Rapid Endonucleolytic Cleavage in Human Leukemia Cells 1

L. Zwelling, D. Farquhar, A. Cherif, 2006 .

N-(5,5-diacetoxypentyl)doxorubicin: a novel anthracycline producing DNA interstrand cross-linking and rapid endonucleolytic cleavage in human leukemia cells.

L. Zwelling, D. Farquhar, A. Cherif, 1991, Cancer research.

Effect of thiols on micronucleus frequency in γ-irradiated mammalian cells

D. Murray, W. Brock, A. Prager, 1991 .

Development of an assay for H2-receptor antagonists using isolated fat cells.

D. Colton, E. Altschuler, E. J. Kulyk, 1980, Journal of Pharmacological Methods.