D. Gagne

发表

Prolonged treatment of breast cancer cells with antiestrogens increases the activating protein-1-mediated response: involvement of the estrogen receptor.

M. Astruc, P. Bali, C. Chabret, 1995, Endocrinology.

Description and analysis of differential sensitivity to glucocorticoids in Fao cells.

D. Gagne, M. Pons, M. Labhilili, 1988, Journal of steroid biochemistry.

Antiestrogenic effects of all-trans-retinoic acid and 1,25-dihydroxyvitamin D3 in breast cancer cells occur at the estrogen response element level but through different molecular mechanisms.

J. Nicolas, P. Balaguer, F. Trousse, 1994, Cancer research.

A model of antiglucocorticoid action for designing a potent glucocorticoid antagonist.

D. Gagne, M. Pons, 1988, Journal of steroid biochemistry.

Regulation of ERK1/2 activity by ghrelin‐activated growth hormone secretagogue receptor 1A involves a PLC/PKCɛ pathway

Jean Martinez, J. Fehrentz, C. Oiry, 2006 .

CholecystokininB receptor from human Jurkat lymphoblastic T cells is involved in activator protein-1-responsive gene activation.

M. Le Cunff, E. Cottin, J. Léger, 1997, Molecular pharmacology.

JMV641: A potent bombesin receptor antagonist that inhibits Swiss 3T3 cell proliferation

J. Fehrentz, M. Llinares, J. Azay, 1996, Regulatory Peptides.

C-terminal heptapeptide of gastrin inhibits astrocytomas motility by interacting with a new gastrin binding site.

R. Kiss, Jean Martinez, I. Camby, 2002, The Journal of pharmacology and experimental therapeutics.

New trisubstituted 1,2,4-triazole derivatives as potent ghrelin receptor antagonists. 3. Synthesis and pharmacological in vitro and in vivo evaluations.

V. Locatelli, A. Torsello, A. Moulin, 2008, Journal of medicinal chemistry.

Toward potent ghrelin receptor ligands based on trisubstituted 1,2,4-triazole structure. 2. Synthesis and pharmacological in vitro and in vivo evaluations.

V. Locatelli, A. Torsello, A. Heitz, 2007, Journal of medicinal chemistry.

Synthesis and pharmacological in vitro and in vivo evaluations of novel triazole derivatives as ligands of the ghrelin receptor. 1.

V. Locatelli, A. Torsello, A. Heitz, 2007, Journal of medicinal chemistry.

Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling*

Jean Martinez, J. Fehrentz, S. Denoyelle, 2015, The Journal of Biological Chemistry.

The third intracellular loop of the rat and mouse cholecystokinin-A receptors is responsible for different patterns of gene activation.

S. Silvente-Poirot, C. Escrieut, D. Fourmy, 2000, Molecular pharmacology.

CCK-B receptor activation in human lymphoblastic Jurkat cells results in AP-1 responsive genes activation

E. Cottin, J. Azay, C. Oiry, 2002 .

Cholecystokinin 1 receptor modulates the MEKK1‐induced c‐Jun trans‐activation: structural requirements of the receptor

Jean Martinez, C. Escrieut, D. Fourmy, 2006, British journal of pharmacology.

Regulation of ERK1/2 activity by ghrelin-activated growth hormone secretagogue receptor 1A involves a PLC/PKCvarepsilon pathway.

Jean Martinez, J. Fehrentz, C. Oiry, 2006, British journal of pharmacology.

New ligands of the ghrelin receptor based on the 1,2,4-triazole scaffold by introduction of a second chiral center.

A. Blayo, Jean Martinez, J. Fehrentz, 2016, Bioorganic & medicinal chemistry letters.

Selenazolidine: a selenium containing proline surrogate in peptide science.

C. Enjalbal, S. Cantel, G. Subra, 2016, Organic & biomolecular chemistry.

A new cellular model of response to estrogens: a bioluminescent test to characterize (anti) estrogen molecules.

D Gagne, J. Nicolas, M. Mehtali, 1990, BioTechniques.

GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation

H. Hamm, G. Ferry, J. Boutin, 2018, Proceedings of the National Academy of Sciences.

Steroid-induced inhibition of nucleoside uptake in isolated mouse thymocytes.

D. Duval, D. Gagne, F. Homo, 1980, Biochimica et biophysica acta.

Glucocorticoid receptors and their functions in lymphocytes.

D. Duval, M. Dardenne, F. Picard, 1980, Journal of steroid biochemistry.

Cross-interactions of Two p38 Mitogen-activated Protein (MAP) Kinase Inhibitors and Two Cholecystokinin (CCK) Receptor Antagonists with the CCK1 Receptor and P38 MAP Kinase*

Jean Martinez, C. Oiry, D. Gagne, 2005, Journal of Biological Chemistry.

RU 38486: a potent antiglucocorticoid in vitro and in vivo.

D. Philibert, D. Gagne, M. Pons, 1985, Journal of steroid biochemistry.

Analysis of the relation between receptor binding affinity and antagonist efficacy of antiglucocorticoids.

A. Crastes de Paulet, D. Gagne, M. Pons, 1986, Journal of steroid biochemistry.

New trisubstituted 1,2,4-triazoles as ghrelin receptor antagonists.

A. Blayo, Jean Martinez, J. Fehrentz, 2015, Bioorganic & medicinal chemistry letters.

Homogeneous time-resolved fluorescence-based assay to screen for ligands targeting the growth hormone secretagogue receptor type 1a.

T. Roux, Emmanuel Bourrier, L. Lamarque, 2011, Analytical biochemistry.

Activation of the ghrelin receptor is described by a privileged collective motion: a model for constitutive and agonist-induced activation of a sub-class A G-protein coupled receptor (GPCR).

David Perahia, Nicolas Floquet, D. Pérahia, 2010, Journal of molecular biology.

Study of an antiestrogenic effect of retinoic acid in MCF-7 cells.

P. Balaguer, E. Demirpençe, D. Gagne, 1992, Biochemical and biophysical research communications.

Stable luciferase transfected cells for studying steroid receptor biological activity.

J. Nicolas, P. Balaguer, F. Trousse, 1994, Journal of bioluminescence and chemiluminescence.

MVLN Cells: A bioluminescent MCF-7-derived cell line to study the modulation of estrogenic activity

E. Demirpençe, É. Badia, M. Duchesne, 1993, The Journal of Steroid Biochemistry and Molecular Biology.

The novel nonapeptide acein targets angiotensin converting enzyme in the brain and induces dopamine release

M. Kemel, P. Marin, S. Cantel, 2016, British journal of pharmacology.

In vitro and in vivo interactions between nuclear receptors at estrogen response elements

J. Nicolas, P. Balaguer, D. Gagne, 1996, The Journal of Steroid Biochemistry and Molecular Biology.

Cholecystokinin receptor parameters responsible for specific cellular signalling

Jean Martinez, D. Fourmy, D. Gagne, 1999 .

Quantitative MALDI‐MS Binding Assays: An Alternative to Radiolabeling

C. Enjalbal, S. Cantel, Jean Martínez, 2016, ChemMedChem.

Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex

D. Pérahia, E. Trinquet, B. Mouillac, 2015, Proceedings of the National Academy of Sciences.

[Retinoic acid has an antiestrogenic effect on different regulated estrogen genes in different cellular types].

H. Gronemeyer, J. Nicolas, M. Bocquel, 1991, Comptes rendus des seances de la Societe de biologie et de ses filiales.

[Modulation of cellular response expression during prolonged treatment with antiestrogens].

J. Nicolas, M. Astruc, É. Badia, 1995, Comptes rendus des seances de la Societe de biologie et de ses filiales.

Selective homodimerization of unprotected peptides using hybrid hydroxydimethylsilane derivatives

Jean Martínez, J. Fehrentz, J. Marie, 2016 .

Agonism, Antagonism, and Inverse Agonism Bias at the Ghrelin Receptor Signaling*

Jean Martinez, J. Fehrentz, S. Denoyelle, 2015, The Journal of Biological Chemistry.