R. Zindell

发表

Selective CB2 receptor agonists. Part 1: the identification of novel ligands through computer-aided drug design (CADD) approaches.

P. Cirillo, E. Hickey, M. Gemkow, 2015, Bioorganic & medicinal chemistry letters.

5-Aminomethylbenzimidazoles as potent ITK antagonists.

J. Woska, D. Jeanfavre, M. Kashem, 2009, Bioorganic & medicinal chemistry letters.

Trifluoromethyl group as a pharmacophore: effect of replacing a CF3 group on binding and agonist activity of a glucocorticoid receptor ligand.

G. Nabozny, Ljiljana Žuvela-Jelaska, D. Kuzmich, 2005, Bioorganic & medicinal chemistry letters.

Selective CB2 receptor agonists. Part 3: the optimization of a piperidine-based series that demonstrated efficacy in an in vivo neuropathic pain model.

P. Cirillo, E. Hickey, A. Bartolozzi, 2015, Bioorganic & medicinal chemistry letters.

Selective CB2 receptor agonists. Part 2: Structure-activity relationship studies and optimization of proline-based compounds.

E. Hickey, M. Gemkow, A. Ceci, 2015, Bioorganic & medicinal chemistry letters.

Aryl 1,4-diazepane compounds as potent and selective CB2 agonists: optimization of drug-like properties and target independent parameters.

Sabine Löbbe, M. Gemkow, Mita Patel, 2011, Bioorganic & medicinal chemistry letters.

Morpholine containing CB2 selective agonists.

Sabine Löbbe, A. Ebneth, M. Gemkow, 2009, Bioorganic & medicinal chemistry letters.

Discovery and optimization of oxadiazole-based FLAP inhibitors.

Asitha Abeywardane, J. M. Hutzler, A. Bartolozzi, 2017, Bioorganic & medicinal chemistry letters.

Synthesis, SAR, and series evolution of novel oxadiazole-containing 5-lipoxygenase activating protein inhibitors: discovery of 2-[4-(3-{(r)-1-[4-(2-amino-pyrimidin-5-yl)-phenyl]-1-cyclopropyl-ethyl}-[1,2,4]oxadiazol-5-yl)-pyrazol-1-yl]-N,N-dimethyl-acetamide (BI 665915).

M. Hao, Asitha Abeywardane, T. Morwick, 2015, Journal of medicinal chemistry.

Identification of dissociated non-steroidal glucocorticoid receptor agonists.

J. Proudfoot, P. Reilly, Alison J Kukulka, 2007, Bioorganic & medicinal chemistry letters.

Binding site elucidation of hydantoin-based antagonists of LFA-1 using multidisciplinary technologies: evidence for the allosteric inhibition of a protein--protein interaction.

L. Frye, D. Jeanfavre, L. Tong, 2001, Journal of the American Chemical Society.

Design and synthesis of dipeptide nitriles as reversible and potent Cathepsin S inhibitors.

Yong Wang, Ming-Hong Hao, M. Hao, 2002, Journal of medicinal chemistry.