Jie Wang

发表

Synthesis and Biological Evaluation of C-17-Amino-Substituted Pyrazole-Fused Betulinic Acid Derivatives as Novel Agents for Osteoarthritis Treatment.

Shi-qi Cao, Bintao Hu, Xiaofei Zhang, 2021, Journal of medicinal chemistry.

A small molecule inhibitor of PCSK9 that antagonizes LDL receptor binding via interaction with a cryptic PCSK9 binding groove.

Sanjay Kumar, H. Treutlein, A. Rathi, 2020, Bioorganic & medicinal chemistry.

Discovery of Hexahydrofuro[3,2-b]furans as New Kinase-Selective and Orally Bioavailable JAK3 Inhibitors for the Treatment of Leukemia Harboring a JAK3 Activating Mutant.

Zheng-chao Tu, Zhen Wang, Zhengqiu Li, 2022, Journal of medicinal chemistry.

Design, synthesis and anti-inflammatory evaluation of novel pyrrolo[2,3-d]pyrimidin derivatives as potent JAK inhibitors.

X. Zhai, L. Zang, Nan Jiang, 2019, Bioorganic & medicinal chemistry.

Identification of U937JAK3-M511I Acute Myeloid Leukemia Cells as a Sensitive Model to JAK3 Inhibitor

Zheng-chao Tu, Ke Ding, Zhang Zhang, 2022, Frontiers in Oncology.

Discovery of the First Highly Selective and Broadly Effective Macrocycle-Based Type II TRK Inhibitors that Overcome Clinically Acquired Resistance.

S. Xiang, Xiaoyun Lu, Zheng-chao Tu, 2022, Journal of medicinal chemistry.

JND4135, a New Type II TRK Inhibitor, Overcomes TRK xDFG and Other Mutation Resistance In Vitro and In Vivo

Xiaoyun Lu, Zheng-chao Tu, Ke Ding, 2022, Molecules.

Mtb PKNA/PKNB Dual Inhibition Provides Selectivity Advantages for Inhibitor Design To Minimize Host Kinase Interactions.

G. Bemis, Tiansheng Wang, B. Hanzelka, 2017, ACS medicinal chemistry letters.

Structure-based design of 2,4-diaminopyrimidine derivatives bearing a pyrrolyl group as ALK and ROS1 inhibitors

X. Zhai, Nan Jiang, Daiying Zuo, 2020 .

Design, synthesis, and Structure-Activity Relationships (SAR) of 3-vinylindazole derivatives as new selective tropomyosin receptor kinases (Trk) inhibitors.

Zheng-chao Tu, Sihua Zhu, Ke Ding, 2020, European journal of medicinal chemistry.

Identification of Unique Quinazolone Thiazoles as Novel Structural Scaffolds for Potential Gram-Negative Bacterial Conquerors.

Cheng‐He Zhou, Mohammad Fawad Ansari, Jie Wang, 2021, Journal of medicinal chemistry.

Synthesis and Biological Evaluation of Quinazolonethiazoles as New Potential Conquerors towards Pseudomonas Aeruginosa

Cheng‐He Zhou, N. Battini, Mohammad Fawad Ansari, 2020, Chinese Journal of Chemistry.

Switch type I to type II TRK inhibitors for combating clinical resistance induced by xDFG mutation for cancer therapy.

S. Xiang, Zheng-chao Tu, Ke Ding, 2022, European journal of medicinal chemistry.

Discovery of novel TrkA allosteric inhibitors: Structure-based virtual screening, biological evaluation and preliminary SAR studies

S. Xiang, Xiaoyun Lu, Ke Ding, 2021, European Journal of Medicinal Chemistry.

An exploration of solvent-front region high affinity moiety leading to novel potent ALK & ROS1 dual inhibitors with mutant-combating effects.

X. Zhai, Daiying Zuo, Ming-juan Guo, 2019, Bioorganic & medicinal chemistry.

Discovery of 3-Aminopyrazole Derivatives as New Potent and Orally Bioavailable AXL Inhibitors.

Licheng Zhou, H. Hur, Zhen Wang, 2022, Journal of medicinal chemistry.

Structure-Based Optimization of the Third Generation Type II Macrocycle TRK Inhibitors with Improved Activity against Solvent-Front, xDFG, and Gatekeeper Mutations.

Ke Ding, Zhang Zhang, Zhi-Min Zhang, 2023, Journal of medicinal chemistry.

Simulation study on inhibition performance of hydrate cellulose kinetic inhibitors for drilling in marine gas-bearing formations

Xu‐Rong Luo, Jie Wang, Panyang Guo, 2023, Arabian Journal of Chemistry.