Z. Brown

发表

Regulatory T cells in human disease and their potential for therapeutic manipulation

D. Robinson, C. Hawrylowicz, A. Akbar, 2006, Immunology.

Potent and Efficacious Inhibition of CXCR2 Signaling by Biparatopic Nanobodies Combining Two Distinct Modes of Action

S. Charlton, T. Laeremans, B. Dombrecht, 2015, Molecular Pharmacology.

SB265610 is an allosteric, inverse agonist at the human CXCR2 receptor

Z. Brown, J. Manini, M. Bradley, 2009, British journal of pharmacology.

The role of 1α,25‐dihydroxyvitamin D3 and cytokines in the promotion of distinct Foxp3+and IL‐10+ CD4+ T cells

C. Hawrylowicz, A. Bush, A. O’Garra, 2012, European journal of immunology.

Discovery of Fevipiprant (NVP-QAW039), a Potent and Selective DP2 Receptor Antagonist for Treatment of Asthma.

D. Budd, S. Watson, S. Charlton, 2017, ACS medicinal chemistry letters.

Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect.

Helinor J Johnston, Christopher S. Stevenson, C. Stevenson, 2005, American journal of physiology. Lung cellular and molecular physiology.

7-Azaindole-3-acetic acid derivatives: potent and selective CRTh2 receptor antagonists.

C. Leblanc, D. Budd, S. Watson, 2009, Bioorganic & medicinal chemistry letters.

2-Cycloalkyl phenoxyacetic acid CRTh2 receptor antagonists.

S. Whitebread, C. Leblanc, D. Budd, 2007, Bioorganic & medicinal chemistry letters.

Ligation of TLR9 induced on human IL-10-secreting Tregs by 1alpha,25-dihydroxyvitamin D3 abrogates regulatory function.

E. Hickman, C. Hawrylowicz, C. Corrigan, 2009, The Journal of clinical investigation.

Evidence that phospholipase C‐dependent, calcium‐independent mechanisms are required for directional migration of T lymphocytes in response to the CCR4 ligands CCL17 and CCL22

R. Parry, S. G. Ward, Darran G. Cronshaw, 2006, Journal of leukocyte biology.

Synthesis and evaluation of two series of 4'-aza-carbocyclic nucleosides as adenosine A2A receptor agonists.

J. Fozard, S. Charlton, P. Gedeck, 2010, Bioorganic & medicinal chemistry letters.

Chemokine Is a Dispensable Signal for T the CCR4 Ligand Macrophage-Derived Activation of Phosphoinositide 3-Kinases by

S. Ward, Darran G. Cronshaw, Z. Brown, 2013 .

Activation of Phosphoinositide 3-Kinases by the CCR4 Ligand Macrophage-Derived Chemokine Is a Dispensable Signal for T Lymphocyte Chemotaxis1

S. Ward, Darran G. Cronshaw, Z. Brown, 2004, The Journal of Immunology.

Lymphocyte Chemotaxis Chemokine Is a Dispensable Signal for T the CCR 4 Ligand Macrophage-Derived Activation of Phosphoinositide 3-Kinases

S. Ward, Z. Brown, C. Owen, 2004 .

Discovery and characterization of NVP-QAV680, a potent and selective CRTh2 receptor antagonist suitable for clinical testing in allergic diseases.

Cerys Docx, J. Westwick, C. Leblanc, 2013, Bioorganic & medicinal chemistry.

The discovery of potent, orally bioavailable pyrazolo and triazolopyrimidine CXCR2 receptor antagonists.

D. O'connor, S. Watson, S. Charlton, 2014, Bioorganic & medicinal chemistry letters.

p38 MAPK signalling cascades in inflammatory disease.

Z. Brown, E. Herlaar, Z. Brown, 1999, Molecular medicine today.

Design and synthesis of a library of chemokine antagonists.

T. Keller, S. Charlton, David Beer, 2011, Bioorganic & medicinal chemistry letters.