A. Thackray

发表

Bioassay of prion-infected blood plasma in PrP transgenic Drosophila.

O. Andréoletti, R. Bujdoso, A. Thackray, 2016, The Biochemical journal.

Perturbation of T‐cell development by insertional mutation of a PrP transgene

M. Zabel, W. Rens, R. Bujdoso, 2009, Immunology.

The emergence of classical BSE from atypical/Nor98 scrapie

R. Bolea, J. Badiola, O. Andréoletti, 2019, Proceedings of the National Academy of Sciences.

Mammalian prion propagation in PrP transgenic Drosophila

O. Andréoletti, R. Bujdoso, A. Thackray, 2018, Brain : a journal of neurology.

Mammalian prions replicate in PrP transgenic Drosophila

O. Andréoletti, R. Bujdoso, A. Thackray, 2018 .

Ovine plasma prion protein levels show genotypic variation detected by C-terminal epitopes not exposed in cell-surface PrPC.

R. Bujdoso, L. Hopkins, T. Fitzmaurice, 2006, The Biochemical journal.

Elevated PrPC Expression Predisposes to Increased HSV-1 Pathogenicity

R. Bujdoso, A. Thackray, 2006, Antiviral chemistry & chemotherapy.

Modification of blood cell PrP epitope exposure during prion disease.

R. Bujdoso, S. Ryder, A. Thackray, 2005, The Biochemical journal.

Subclinical Prion Disease Induced by Oral Inoculation

R. Bujdoso, M. A. Klein, A. Thackray, 2003, Journal of Virology.

Metal imbalance and compromised antioxidant function are early changes in prion disease.

S. Haswell, David R. Brown, R. Bujdoso, 2002, The Biochemical journal.

The trigeminal ganglion is a location for equine herpesvirus 1 latency and reactivation in the horse.

H. Field, J. Slater, K. Borchers, 1994, The Journal of general virology.

Reduced herpes simplex virus type 1 latency in Flt‐3 ligand‐treated mice is associated with enhanced numbers of natural killer and dendritic cells

J. Smith, R. Bujdoso, A. Thackray, 2001, Immunology.

Proteinase K-sensitive disease-associated ovine prion protein revealed by conformation-dependent immunoassay.

R. Bujdoso, L. Hopkins, A. Thackray, 2007, The Biochemical journal.

Comparison of efficacies of famciclovir and valaciclovir against herpes simplex virus type 1 in a murine immunosuppression model

H. Field, D. Tewari, D. Sutton, 1995, Antimicrobial agents and chemotherapy.

The effects of antiviral therapy on the distribution of herpes simplex virus type 1 to ganglionic neurons and its consequences during, immediately following and several months after treatment.

H. Field, A. Thackray, 2000, The Journal of general virology.

Early Therapy with Valaciclovir or Famciclovir Reduces But Does Not Abrogate Herpes Simplex Virus Neuronal Latency

H. Field, A. Thackray, 2000, Nucleosides, nucleotides & nucleic acids.

Further evidence from a murine infection model that famciclovir interferes with the establishment of HSV-1 latent infections.

H. Field, A. Thackray, 2000, The Journal of antimicrobial chemotherapy.

Famciclovir and Valaciclovir Differ in the Prevention of Herpes Simplex Virus Type 1 Latency in Mice: a Quantitative Study

H. Field, A. Thackray, 1998, Antimicrobial Agents and Chemotherapy.

Can Herpes Simplex Virus Latency Be Prevented Using Conventional Nucleoside Analogue Chemotherapy?

H. Field, A. Thackray, H. Field, 1997 .

Persistence of Infectious Herpes Simplex Virus Type 2 in the Nervous System in Mice after Antiviral Chemotherapy

H. Field, A. Thackray, 2000, Antimicrobial Agents and Chemotherapy.

Field after Antiviral Chemotherapy Virus Type 2 in the Nervous System in Mice Persistence of Infectious Herpes Simplex

J. Hugh, A. Thackray, 1999 .

Differential effects of famciclovir and valaciclovir on the pathogenesis of herpes simplex virus in a murine infection model including reactivation from latency.

H. Field, A. Thackray, 1996, The Journal of infectious diseases.

Prion-induced toxicity in PrP transgenic Drosophila.

J. Spiropoulos, D. Crowther, R. Bujdoso, 2012, Experimental and molecular pathology.

The pathogenesis of wild type and drug resistant mutant strains of bovine herpesvirus-1 (BHV-1) in the natural host

H. Field, G. A. Brown, A. Thackray, 2005, Archives of Virology.

Comparison of effects of famciclovir and valaciclovir on pathogenesis of herpes simplex virus type 2 in a murine infection model

H. Field, A. Thackray, 1996, Antimicrobial agents and chemotherapy.

Effects of famciclovir and valacyclovir on herpes simplex virus type 1 infection, latency, and reactivation in mice: how dissimilar are study results?

H. Field, A. Thackray, 2000, The Journal of infectious diseases.

The Effects of Delayed-Onset Chemotherapy using Famciclovir or Valaciclovir in a Murine Immunosuppression Model for HSV-1

A. Thackray, H. Field, 1995 .

Temporal pattern of herpes simplex virus type 1 infection and cell death in the mouse brain stem: influence of guanosine nucleoside analogues.

H. Field, M. Shaw, P. Watts, 2002, Journal of virological methods.

PrPc Expression Influences the Establishment of Herpes Simplex Virus Type 1 Latency

R. Bujdoso, A. Thackray, 2002, Journal of Virology.

Polymorphisms at Amino Acid Residues 141 and 154 Influence Conformational Variation in Ovine PrP

D. Burke, R. Bujdoso, T. Monie, 2014, BioMed research international.

Single protein molecule detection by glass nanopores.

Silvia Hernández-Ainsa, Ulrich F Keyser, Nicholas A. W. Bell, 2013, ACS nano.

Prion-induced neurotoxicity: Possible role for cell cycle activity and DNA damage response.

W. Jackson, M. Landgraf, R. Bujdoso, 2015, World journal of virology.

Prion disease modelled in Drosophila

Andrew Smith, J. Spiropoulos, O. Andréoletti, 2022, Cell and Tissue Research.

Accelerated Prion Disease in the Absence of Interleukin-10

Angus Lauder, A. McKenzie, R. Bujdoso, 2004, Journal of Virology.

Evidence for co-infection of ovine prion strains in classical scrapie isolates.

J. Spiropoulos, R. Bujdoso, K. Beck, 2012, Journal of comparative pathology.

Propagation of ovine prions from "poor" transmitter scrapie isolates in ovine PrP transgenic mice.

J. Spiropoulos, R. Bujdoso, L. Hopkins, 2012, Experimental and molecular pathology.

Emergence of multiple prion strains from single isolates of ovine scrapie.

J. Spiropoulos, R. Bujdoso, L. Hopkins, 2011, The Journal of general virology.

Molecular and Transmission Characteristics of Primary-Passaged Ovine Scrapie Isolates in Conventional and Ovine PrP Transgenic Mice

J. Spiropoulos, R. Bujdoso, L. Hopkins, 2008, Journal of Virology.

A new model for sensitive detection of zoonotic prions by PrP transgenic Drosophila

J. Spiropoulos, O. Andréoletti, R. Bujdoso, 2021, The Journal of biological chemistry.

The stability and aggregation of ovine prion protein associated with classical and atypical scrapie correlates with the ease of unwinding of helix-2.

D. Burke, M. Sy, R. Bujdoso, 2008, The Biochemical journal.

Structural differences between allelic variants of the ovine prion protein revealed by molecular dynamics simulations

D. Burke, R. Bujdoso, A. Thackray, 2005, Proteins.

Prion-induced and spontaneous formation of transmissible toxicity in PrP transgenic Drosophila.

O. Andréoletti, I. Vorberg, R. Bujdoso, 2014, The Biochemical journal.

Cytosolic PrP Can Participate in Prion-Mediated Toxicity

R. Bujdoso, A. Thackray, Tina Arndt, 2014, Journal of Virology.

2-Revised text JVI00732-14 02.05.14

R. Bujdoso, A. Thackray, Tina Arndt, 2014 .

Ovine PrP transgenic Drosophila show reduced locomotor activity and decreased survival.

M. Landgraf, J. Evers, T. Jahn, 2012, The Biochemical journal.

Copper-induced structural changes in the ovine prion protein are influenced by a polymorphism at codon 112.

R. Bujdoso, Sujeong Yang, T. Fitzmaurice, 2008, Biochimica et biophysica acta.

Direct Observation of Murine Prion Protein Replication in Vitro

D. Klenerman, T. Knowles, A. Ponjavic, 2018, Journal of the American Chemical Society.

Direct observation of prion protein oligomer formation reveals an aggregation mechanism with multiple conformationally distinct species† †Electronic supplementary information (ESI) available: Additional methods and materials, supplementary figures. Representative TIRF images of PrP aggregates at dif

D. Klenerman, T. Knowles, Ji-Eun Lee, 2019, Chemical science.

Mouse-Adapted Ovine Scrapie Prion Strains Are Characterized by Different Conformers of PrPSc

R. Bujdoso, L. Hopkins, A. Thackray, 2007, Journal of Virology.

Transcriptional signature of prion-induced neurotoxicity in a Drosophila model of transmissible mammalian prion disease

G. Yeo, R. Bujdoso, B. Lam, 2020, The Biochemical journal.

Serological responses of specific pathogen-free foals to equine herpesvirus-1: primary and secondary infection, and reactivation.

H. Field, D. Hannant, J. Gibson, 1992, Veterinary microbiology.

Genetic human prion disease modelled in PrP transgenic Drosophila

W. Jackson, I. Vorberg, R. Bujdoso, 2017, The Biochemical journal.

Chronic Subclinical Prion Disease Induced by Low-Dose Inoculum

A. Aguzzi, R. Bujdoso, A. Thackray, 2002, Journal of Virology.

An arrayed genome‐wide perturbation screen identifies the ribonucleoprotein Hnrnpk as rate‐limiting for prion propagation

S. Hornemann, A. Aguzzi, M. Polymenidou, 2022, bioRxiv.

The use of PrP transgenic Drosophila to replace and reduce vertebrate hosts in the bioassay of mammalian prion infectivity

O. Andréoletti, R. Bujdoso, A. Thackray, 2018, F1000Research.

Detection of bovine spongiform encephalopathy, ovine scrapie prion-related protein (PrPSc) and normal PrPc by monoclonal antibodies raised to copper-refolded prion protein.

R. Morgan-Warren, David R. Brown, R. Bujdoso, 2003, The Biochemical journal.

Copper induces increased beta-sheet content in the scrapie-susceptible ovine prion protein PrPVRQ compared with the resistant allelic variant PrPARR.

R. Bujdoso, Edmond Wong, A. Thackray, 2004, The Biochemical journal.

Ovine PrP transgenic Drosophila show reduced locomotor activity and decreased survival.

M. Landgraf, J. Evers, T. Jahn, 2012, The Biochemical journal.

Chronic Subclinical Prion Disease Induced by Low-Dose Inoculum

A. Aguzzi, R. Bujdoso, A. Thackray, 2002, Journal of Virology.

Direct Observation of Murine Prion Protein Replication in Vitro

D. Klenerman, T. Knowles, A. Ponjavic, 2018, Journal of the American Chemical Society.

Neuropathological profile of the African Giant Rat brain (Cricetomys gambianus) after natural exposure to heavy metal environmental pollution in the Nigerian Niger Delta

A. Oyagbemi, O. Folarin, J. Olopade, 2023, Environmental Science and Pollution Research.

Single protein molecule detection by glass nanopores.

Vivek V. Thacker, Nicholas A. W. Bell, U. Keyser, 2013, ACS Nano.

Genetic modulation of CWD prion propagation in cervid PrP Drosophila

G. Telling, S. Benestad, R. Bujdoso, 2023, The Biochemical journal.

Lack of prion transmission barrier in human PrP transgenic Drosophila

O. Andréoletti, G. Telling, S. Benestad, 2024, The Journal of biological chemistry.

Conformational variation between allelic variants of cell-surface ovine prion protein.

R. Bujdoso, Robert J. Morgan-Warren, Sujeong Yang, 2004, The Biochemical journal.

The trigeminal ganglion is a location for equine herpesvirus 1 latency and reactivation in the horse.

H. Field, J. Slater, K. Borchers, 1994, The Journal of general virology.