Marcus Jones

发表

Genotyping, sequencing and analysis of 140,000 adults from the Mexico City Prospective Study

Alexander E. Lopez, Katherine R. Smith, R. Collins, 2022, bioRxiv.

Germline Mutations in CIDEB and Protection against Liver Disease.

Johnathon R. Walls, G. Abecasis, H. Kang, 2022, The New England journal of medicine.

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Spiros C. Denaxas, Alexander E. Lopez, Andrew L Blumenfeld, 2020, Nature Communications.

Multiancestry exome sequencing reveals INHBE mutations associated with favorable fat distribution and protection from diabetes

Johnathon R. Walls, Mary E. Haas, R. Collins, 2022, Nature Communications.

Genetic and Functional Characterization of ANGPTL7 as a Therapeutic Target for Glaucoma

Tanya M. Teslovich, Gaurang C. Patel, G. D. Gatta, 2021 .

ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma

Alexander E. Lopez, Tanya M. Teslovich, Gaurang C. Patel, 2022, Communications Biology.

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ethnic meta-analysis

Alexander E. Lopez, Grant D. Huang, Yan V. Sun, 2020, Nature Genetics.

Exome sequencing and analysis of 454,787 UK Biobank participants

J. Marchini, G. Abecasis, H. Kang, 2021, Nature.

Exome sequencing and characterization of 49,960 individuals in the UK Biobank

Alexander E. Lopez, Alexander Hanbo Li, Andrew L Blumenfeld, 2020, Nature.

An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs

Alexander E. Lopez, Aaron M. King, Andrew L Blumenfeld, 2021, Journal of hepatology.

Common and rare variant associations with clonal haematopoiesis phenotypes

J. Marchini, G. Abecasis, H. Kang, 2022, Nature.

Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity

R. Collins, J. Marchini, G. Abecasis, 2021, Science.

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Spiros C. Denaxas, Alexander E. Lopez, Andrew L Blumenfeld, 2020, Nature Communications.

GWAS of serum ALT and AST reveals an association of SLC30A10 Thr95Ile with hypermanganesemia symptoms

Alexander E. Lopez, Dustin N. Hartzel, Andrew L Blumenfeld, 2021, Nature Communications.

Mucus sialylation determines intestinal host-commensal homeostasis

A. Griffiths, N. Warner, C. Bertozzi, 2022, Cell.

Analysis of rare genetic variation underlying cardiometabolic diseases and traits among 200,000 individuals in the UK Biobank

Alexander E. Lopez, David P. vanMaanen, K. Lunetta, 2022, Nature Genetics.

Whole exome sequencing and characterization of coding variation in 49,960 individuals in the UK Biobank

Gonçalo Abecasis, Alan R. Shuldiner, Jeffrey Staples, 2019, bioRxiv.

Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes

Alexander E. Lopez, Andrew L Blumenfeld, M. McCarthy, 2021, Nature Genetics.

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis

Alexander E. Lopez, Yan V. Sun, Andrew L Blumenfeld, 2020, Nature Genetics.

Genome-wide analysis provides genetic evidence that ACE2 influences COVID-19 risk and yields risk scores associated with severe disease

Alexander E. Lopez, Eurie L. Hong, G. D. Gatta, 2022, Nature Genetics.

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

Tom R. Gaunt, Alexander E. Lopez, Laurent F. Thomas, 2021, Cell.

Exome sequencing and characterization of 49,960 individuals in the UK Biobank

Alexander E. Lopez, Andrew L Blumenfeld, J. Marchini, 2020, Nature.

Gene-level analysis of rare variants in 379,066 whole exome sequences identifies an association of GIGYF1 loss of function with type 2 diabetes

Alexander E. Lopez, Dustin N. Hartzel, Andrew L Blumenfeld, 2021, Scientific Reports.

Pan-ancestry exome-wide association analyses of COVID-19 outcomes in 586,157 individuals

J. Marchini, G. Abecasis, H. Kang, 2021, The American Journal of Human Genetics.

A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

Christopher D. Brown, Henry J. Lin, Yan V. Sun, 2021, Nature Genetics.

Advancing Human Genetics Research and Drug Discovery through Exome Sequencing of the UK Biobank

Alexander E. Lopez, Jason A. Grundstad, Sri V. V. Deevi, 2020, medRxiv.

High heritability of ascending aortic diameter and trans-ancestry prediction of thoracic aortic disease

Alexander E. Lopez, Manuel A. Rivas, Manuel A Rivas, 2022, Nature Genetics.

Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction

T. Werge, K. Lage, Yunpeng Wang, 2021, Nature Communications.

MEPE loss-of-function variant associates with decreased bone mineral density and increased fracture risk

Andrew L Blumenfeld, G. Abecasis, H. Kang, 2020, Nature Communications.

Exome sequencing identifies a nonsense variant in DAO associated with reduced energy expenditure in American Indians.

C. Bogardus, R. Hanson, S. Kobes, 2020, The Journal of clinical endocrinology and metabolism.

Impact of natural selection on global patterns of genetic variation, and association with clinical phenotypes, at genes involved in SARS-CoV-2 infection.

Matthew E. B. Hansen, S. Tishkoff, G. Sirugo, 2021, Research square.

Thrombotic Risk Determined by STAB 2 Variants in a Population-Based Cohort Study.

Alexander E. Lopez, Andrew L Blumenfeld, G. Abecasis, 2021, Circulation. Genomic and precision medicine.

Polygenic Risk of Psychiatric Disorders Exhibits Cross-trait Associations in Electronic Health Record Data From European Ancestry Individuals

Alexander E. Lopez, Andrew L Blumenfeld, G. Abecasis, 2020, Biological Psychiatry.

Corrigendum to ‘An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs’ [J Hepatol 2021;75(3):572–581]

Alexander E. Lopez, Aaron M. King, Andrew L Blumenfeld, 2021, Journal of hepatology.

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Spiros C. Denaxas, Alexander E. Lopez, Andrew L Blumenfeld, 2020, Nature Communications.

Converging evidence from exome sequencing and common variants implicates target genes for osteoporosis

G. Abecasis, C. Greenwood, J. Richards, 2023, Nature Genetics.

A catalog of associations between rare coding variants and COVID-19 outcomes

Alexander Hanbo Li, J. Marchini, G. Abecasis, 2020, medRxiv.

Genome-wide analysis of individual coding variants and HLA-II-associated self-immunopeptidomes in ulcerative colitis

M. Laudes, D. Ellinghaus, L. Wienbrandt, 2023, medRxiv.

Seroprevalence of Anti-SARS-CoV-2 Antibodies in a Cohort of New York City Metro Blood Donors using Multiple SARS-CoV-2 Serological Assays: Implications for Controlling the Epidemic and Reopening.

Daniel J. Nesbitt, C. Hillyer, C. Kyratsous, 2020, medRxiv.

A multiancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

Christopher D. Brown, Henry J. Lin, Yan V. Sun, 2022, Nature Genetics.

Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank

Sri V. V. Deevi, J. Szustakowski, S. Balasubramanian, 2021, Nature Genetics.

A trans-ancestry genome-wide association study of unexplained chronic ALT elevation as a proxy for nonalcoholic fatty liver disease with histological and radiological validation

Anurag, Mary E. Haas, B. Neuschwander‐Tetri, 2021 .

Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations

Tom R. Gaunt, Alexander E. Lopez, Laurent F. Thomas, 2021, Cell.

Genotyping, sequencing and analysis of 140,000 adults from Mexico City

R. Collins, S. Balasubramanian, A. Hawes, 2023, Nature.

Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure

Alexander E. Lopez, Andrew L Blumenfeld, J. Cook, 2020, Nature Communications.

Seroprevalence of anti-SARS-CoV-2 antibodies in a cohort of New York City metro blood donors using multiple SARS-CoV-2 serological assays: Implications for controlling the epidemic and “Reopening”

Daniel J. Nesbitt, C. Hillyer, C. Kyratsous, 2020, medRxiv.