Merrill Ayres

Discovery of AMG 925, a FLT3 and CDK4 dual kinase inhibitor with preferential affinity for the activated state of FLT3.

K. Pattabiraman, Zhulun Wang, C. Quéva, 2014, Journal of medicinal chemistry.

An ultrasensitive high-throughput electrochemiluminescence immunoassay for the Cdc42-associated protein tyrosine kinase ACK1.

Rajiv Sharma, J. Anzola, Jinqian Liu, 2007, Analytical biochemistry.

Structure of the Nuclear Factor κB-inducing Kinase (NIK) Kinase Domain Reveals a Constitutively Active Conformation

N. Walker, Z. Cao, O. Plotnikova, 2012, The Journal of Biological Chemistry.

Crystal structures of IRAK-4 kinase in complex with inhibitors: a serine/threonine kinase with tyrosine as a gatekeeper.

N. Walker, Zhulun Wang, Jinsong Liu, 2006, Structure.

Inhibiting NF-κB-inducing kinase (NIK): discovery, structure-based design, synthesis, structure-activity relationship, and co-crystal structures.

O. Plotnikova, Zhulun Wang, Jinsong Liu, 2013, Bioorganic & medicinal chemistry letters.

Structural and Functional Characterization of the JH2 Pseudokinase Domain of JAK Family Tyrosine Kinase 2 (TYK2)*

C. Gabel, O. Silvennoinen, N. Walker, 2015, The Journal of Biological Chemistry.

Discovery of AMG 925, a FLT3 and CDK4 dual kinase inhibitor with preferential affinity for the activated state of FLT3.

K. Pattabiraman, Zhulun Wang, C. Quéva, 2014, Journal of medicinal chemistry.