P. Hargrove

发表

Potentially therapeutic levels of anti-sickling globin gene expression following lentivirus-mediated gene transfer in sickle cell disease bone marrow CD34+ cells.

Michael L Kaufman, D. Kohn, D. Persons, 2015, Experimental hematology.

Therapeutic levels of fetal hemoglobin in erythroid progeny of β-thalassemic CD34+ cells after lentiviral vector-mediated gene transfer.

S. Orkin, A. Nienhuis, N. Anagnou, 2011, Blood.

primary human adult erythroblasts -globin gene promoters enhances fetal hemoglobin production in γ A zinc-finger transcriptional activator designed to interact with the

U. Tschulena, A. Nienhuis, D. Persons, 2011 .

A zinc-finger transcriptional activator designed to interact with the gamma-globin gene promoters enhances fetal hemoglobin production in primary human adult erythroblasts.

C. Barbas, U. Tschulena, A. Nienhuis, 2010, Blood.

Gene transfer into hematopoietic cells

A. Nienhuis, E. Vanin, J. Bertran, 1997, Stem cells.

High-efficiency transduction and long-term gene expression with a murine stem cell retroviral vector encoding the green fluorescent protein in human marrow stromal cells.

J. Allay, D. Persons, E. Horwitz, 1999, Human gene therapy.

Globin lentiviral vector insertions can perturb the expression of endogenous genes in beta-thalassemic hematopoietic cells.

J. Gray, Cheng Cheng, G. Neale, 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

Amelioration of murine sickle cell disease by nonablative conditioning and γ-globin gene-corrected bone marrow cells

M. Weiss, D. Persons, A. Wilber, 2015, Molecular therapy. Methods & clinical development.

Correction of Murine Sickle Cell Disease Using γ-Globin Lentiviral Vectors to Mediate High-level Expression of Fetal Hemoglobin.

J. Gray, D. Persons, T. Pestina, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

High-level globin gene expression mediated by a recombinant adeno-associated virus genome that contains the 3' gamma globin gene regulatory element and integrates as tandem copies in erythroid cells.

A. Nienhuis, G. Kurtzman, E. Vanin, 1997, Blood.

Behavioral and molecular effects of Ubtf knockout and knockdown in mice

Roderick T. Hori, M. LeDoux, T. Moss, 2022, Brain Research.

Amelioration of murine beta-thalassemia through drug selection of hematopoietic stem cells transduced with a lentiviral vector encoding both gamma-globin and the MGMT drug-resistance gene.

Perdeep K. Mehta, D. Persons, M. Nasimuzzaman, 2009, Blood.

High-efficiency transduction of rhesus hematopoietic repopulating cells by a modified HIV1-based lentiviral vector.

T. Wolfsberg, A. Nguyen, J. Tisdale, 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

The degree of phenotypic correction of murine beta -thalassemia intermedia following lentiviral-mediated transfer of a human gamma-globin gene is influenced by chromosomal position effects and vector copy number.

A. Nienhuis, D. Persons, E. Allay, 2003, Blood.

Extended β-globin locus control region elements promote consistent therapeutic expression of a γ-globin lentiviral vector in murine β-thalassemia

D. Srivastava, A. Nienhuis, D. Persons, 2004 .

Extended beta-globin locus control region elements promote consistent therapeutic expression of a gamma-globin lentiviral vector in murine beta-thalassemia.

D. Srivastava, A. Nienhuis, D. Persons, 2004, Blood.

Comparison of various envelope proteins for their ability to pseudotype lentiviral vectors and transduce primitive hematopoietic cells from human blood.

Jody A. Vandergriff, A. Nienhuis, D. Persons, 2002, Molecular therapy : the journal of the American Society of Gene Therapy.

Transduction of human primitive repopulating hematopoietic cells with lentiviral vectors pseudotyped with various envelope proteins.

A. Nienhuis, J. Gray, D. Persons, 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

Targeted Integration of a Recombinant Globin Gene Adeno‐Associated Viral Vector into Human Chromosome 19 a

A. Nienhuis, J. Bertran, E. Vanin, 1998, Annals of the New York Academy of Sciences.

Correction of murine sickle cell disease using gamma-globin lentiviral vectors to mediate high-level expression of fetal hemoglobin.

J. Gray, D. Persons, T. Pestina, 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

Successful treatment of murine beta-thalassemia using in vivo selection of genetically modified, drug-resistant hematopoietic stem cells.

A. Nienhuis, T. Brent, B. Sorrentino, 2003, Blood.

In vivo bioluminescence imaging for early detection and monitoring of disease progression in a murine model of neuroblastoma.

A. Davidoff, M. B. McCarville, Blair Hamner, 2007, Journal of pediatric surgery.

530. Lentiviral Vector Particles Pseudotyped with Wild-Type Baboon Endogenous Retrovirus (BAEV) Glycoprotein Outperform VSV-G Particles in Transducing Human CD34+ Cells Isolated from Cytokine-Mobilized Peripheral Blood or Bone Marrow

A. Nienhuis, Yoon-Sang Kim, M. Wielgosz, 2016 .