Giulia Fani

Partial Failure of Proteostasis Systems Counteracting TDP-43 Aggregates in Neurodegenerative Diseases

F. Chiti, C. Cecchi, R. Cascella, 2019, International journal of molecular sciences.

Quantification of the Relative Contributions of Loss-of-function and Gain-of-function Mechanisms in TAR DNA-binding Protein 43 (TDP-43) Proteinopathies *

C. Dobson, F. Chiti, C. Cecchi, 2016, The Journal of Biological Chemistry.

Misfolded protein oligomers induce an increase of intracellular Ca2+ causing an escalation of reactive oxidative species

M. Vendruscolo, F. Chiti, C. Cecchi, 2022, Cellular and Molecular Life Sciences.

Studying the trafficking of labeled trodusquemine and its application as nerve marker for light‐sheet and expansion microscopy

F. Chiti, L. Pesce, Martino Calamai, 2022, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Sphingosine 1‐phosphate attenuates neuronal dysfunction induced by amyloid‐β oligomers through endocytic internalization of NMDA receptors

F. Chiti, P. Bruni, C. Cecchi, 2022, The FEBS journal.

Aβ Oligomers Dysregulate Calcium Homeostasis by Mechanosensitive Activation of AMPA and NMDA Receptors

C. Dobson, M. Vendruscolo, F. Chiti, 2021, ACS chemical neuroscience.

Differential interactome and innate immune response activation of two structurally distinct misfolded protein oligomers.

C. Dobson, C. Roodveldt, M. Vendruscolo, 2019, ACS chemical neuroscience.

Full-length TDP-43 and its C-terminal domain form filaments in vitro having non-amyloid properties

Lisa D. Cabrita, F. Chiti, M. Vivoli Vega, 2020, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

Isolation and characterization of soluble human full‐length TDP‐43 associated with neurodegeneration

F. Chiti, F. Boscaro, S. Luti, 2019, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Quantitative assessment of the degradation of aggregated TDP‐43 mediated by the ubiquitin proteasome system and macroautophagy

F. Chiti, A. Poletti, C. Cecchi, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Soluble Prion Peptide 107–120 Protects Neuroblastoma SH-SY5Y Cells against Oligomers Associated with Alzheimer’s Disease

F. Chiti, C. Cecchi, S. Hosseini, 2020, International journal of molecular sciences.

Mechanosensitivity of N-methyl-D-aspartate receptors (NMDAR) is the key through which amyloid beta oligomers activate them

F. Chiti, Giulia Fani, 2021, Neural regeneration research.