Wenbao Li

发表

Biological activity and interaction mechanism of the diketopiperazine derivatives as tubulin polymerization inhibitors

Hui Wang, Yan-yan Chu, Zhenhua Tian, 2018, RSC advances.

Development of M10, myricetin-3-O-β-d-lactose sodium salt, a derivative of myricetin as a potent agent of anti-chronic colonic inflammation.

Xian-Jun Qu, Shixiao Wang, Zhi-yu Song, 2019, European journal of medicinal chemistry.

SL1122-37, a novel derivative of sorafenib, has greater effects than sorafenib on the inhibition of human hepatocellular carcinoma (HCC) growth and prevention of angiogenesis.

Xian-Jun Qu, Ruiqi Wang, Wenbao Li, 2013, Bioscience trends.

Pharmacokinetics and metabolism of SL-01, a prodrug of gemcitabine, in rats

Xian-Jun Qu, Cui-rong Zhao, Ruiqi Wang, 2013, Cancer Chemotherapy and Pharmacology.

SL-01, an oral gemcitabine derivative, inhibited human cancer growth more potently than gemcitabine.

Xian-Jun Qu, B. Yue, Cui-rong Zhao, 2012, Toxicology and applied pharmacology.

Synthesis of deuterium-enriched and fluorine-substituted plinabulin derivatives and evaluation of their antitumor activities

Huashi Guan, Shixiao Wang, Tianwen Sun, 2017, Molecular Diversity.

Combinatorial synthesis of deuterium-enriched (S)-oxybutynin

A. W. Czarnik, Feng Li, Wenbao Li, 2016, Molecular Diversity.

Polymorphs, co-crystal structure and pharmacodynamics study of MBRI-001, a deuterium-substituted plinabulin derivative as a tubulin polymerization inhibitor.

Shixiao Wang, Yuxi Wang, Jinliang Yang, 2019, Bioorganic & medicinal chemistry.

Synthesis and Biological Evaluation of Oral Prodrugs Based on the Structure of Gemcitabine

Xian-Jun Qu, X. Xue, Cui-rong Zhao, 2012, Chemical biology & drug design.

Combination of a novel microtubule inhibitor MBRI-001 and gemcitabine synergistically induces cell apoptosis by increasing DNA damage in pancreatic cancer cell lines

Xin Wang, Jinbo Yang, Ruochen Zang, 2019, Investigational New Drugs.

Study on the Preparation and Antileukemic Activity of New Lipophilic 1-β-D-arabinofuranosylcytosine Derivatives

Yan-yan Chu, Zhenhua Tian, Wenbao Li, 2018, Journal of Ocean University of China.

Design and Synthesis of Novel Phenylahistin Derivatives Based on Co-Crystal Structures as Potent Microtubule Inhibitors for Anti-Cancer Therapy

Chang Liu, Chunlei Li, Chao Peng, 2022, Marine drugs.

Development of MBRI-001, a deuterium-substituted plinabulin derivative as a potent anti-cancer agent.

Huashi Guan, Shixiao Wang, Hua-shi Guan, 2017, Bioorganic & medicinal chemistry letters.

Design, synthesis, and biological evaluation of novel stachydrine derivatives as potent neuroprotective agents for cerebral ischemic stroke

Liang Zhang, Feng Li, Lili Zhong, 2020, Naunyn-Schmiedeberg's Archives of Pharmacology.

Design, synthesis, and biological evaluation of novel stachydrine derivatives as potent neuroprotective agents for cerebral ischemic stroke

Cai Song, Liang Zhang, Feng Li, 2020, Naunyn-Schmiedeberg's Archives of Pharmacology.

Design, synthesis and biological evaluation of anti-pancreatic cancer activity of plinabulin derivatives based on the co-crystal structure.

Yan-yan Chu, Ming‐jie Ma, Zhenhua Tian, 2018, Bioorganic & medicinal chemistry.

Synthesis of myricetin derivatives and evaluation of their hypoglycemic activities

Liang Zhang, Feng Li, Wenbao Li, 2022, Medicinal Chemistry Research.

Development of novel phenoxy-diketopiperazine-type plinabulin derivatives as potent antimicrotubule agents based on the co-crystal structure.

Cai Song, Shixiao Wang, Yan-yan Chu, 2019, Bioorganic & medicinal chemistry.

Seahorse treatment improves depression-like behavior in mice exposed to CUMS through reducing inflammation/oxidants and restoring neurotransmitter and neurotrophin function.

A. Kalueff, Cai Song, Cai Zhang, 2019, Journal of ethnopharmacology.

Structure-based design and synthesis of novel furan-diketopiperazine-type derivatives as potent microtubule inhibitors for treating cancer.

Shixiao Wang, Feng Li, Wenbao Li, 2020, Bioorganic & medicinal chemistry.

In vitro and in vivo pharmacokinetic and pharmacodynamic study of MBRI-001, a deuterium-substituted plinabulin derivative as a potent anti-cancer agent.

G. Dou, Ming‐jie Ma, Feng Li, 2018, Bioorganic & medicinal chemistry.

Synthesis of deuterium-enriched and fluorine-substituted plinabulin derivatives and evaluation of their antitumor activities

Shixiao Wang, Tianwen Sun, Hua-shi Guan, 2017, Molecular Diversity.

Combinatorial synthesis of deuterium-enriched (S)-oxybutynin

A. W. Czarnik, Feng Li, Wenbao Li, 2016, Molecular Diversity.

Synthesis of deuterium-enriched sorafenib derivatives and evaluation of their biological activities

Liang Zhang, Feng Li, Lili Zhong, 2018, Molecular Diversity.