K. O’Loughlin

发表

Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones

David M. Shackleford, R. Guy, S. Charman, 2020, Malaria journal.

Metabolism, Pharmacokinetics, Tissue Distribution, and Stability Studies of the Prodrug Analog of an Anti-Hepatitis B Virus Dinucleoside Phosphorothioate

R. Pandey, R. Iyer, C. Green, 2012, Drug Metabolism and Disposition.

Metabolism, pharmacokinetics, tissue distribution, and stability studies of the prodrug analog of an anti-HBV dinucleoside phosphorothioate

R. Pandey, R. Iyer, C. Green, 2012 .

Efﬁcacy of Tilorone Dihydrochloride against Ebola Virus Infection

S. Ekins, C. Green, Alexander N. Freiberg, 2018 .

(R,S)-Ketamine Metabolites (R,S)-norketamine and (2S,6S)-hydroxynorketamine Increase the Mammalian Target of Rapamycin Function

M. Bernier, M. Torjman, M. Sanghvi, 2014, Anesthesiology.

Subchronic administration of (R,S)-ketamine induces ketamine ring hydroxylation in Wistar rats.

M. Torjman, M. Sanghvi, C. Green, 2016, Journal of pharmaceutical and biomedical analysis.

The distribution and clearance of (2S,6S)-hydroxynorketamine, an active ketamine metabolite, in Wistar rats

M. Sanghvi, C. Green, R. Moaddel, 2015, Pharmacology research & perspectives.

Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection

S. Ekins, C. Green, Alexander N. Freiberg, 2017, Antimicrobial Agents and Chemotherapy.

Orally bioavailable anti-HBV dinucleotide acyloxyalkyl prodrugs.

R. Iyer, C. Green, J. Mirsalis, 2010, Bioorganic & medicinal chemistry letters.

Pharmacokinetics and dose-range finding toxicity of a novel anti-HIV active integrase inhibitor.

J. Mirsalis, V. Nair, Maurice O Okello, 2014, Antiviral research.

Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus

Joshua C. Johnson, P. Shinn, R. Guha, 2016, PloS one.

(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium

Hongshen Ma, Zheng Wang, Jeremy Horst, 2014, Proceedings of the National Academy of Sciences.

Radiation-induced point mutations, deletions and micronuclei in lacI transgenic mice.

J. D. Hamer, J. Mirsalis, R. Winegar, 1994, Mutation research.

Formulation approaches to improving the delivery of an antiviral drug with activity against seasonal flu

C. Green, Shravan K Mutyam, G. Shankar, 2015, Pharmaceutical development and technology.

Induction of hepatic mutations in lacI transgenic mice.

J. T. Macgregor, J. Short, J. Mirsalis, 1993, Mutagenesis.

Chromium (VI) at plausible drinking water concentrations is not genotoxic in the in vivo bone marrow micronucleus or liver unscheduled DNA synthesis assays

D. Paustenbach, S. Patierno, B. Kerger, 1996, Environmental and molecular mutagenesis.

Determination of tissue distribution of an intramuscular plasmid vaccine using PCR and in situ DNA hybridization.

J. T. Macgregor, C. Rudd, R. Winegar, 1996, Human gene therapy.

Erratum: (+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium (Proceedings of the National Academy of Sciences of the United States of America (2014) 111 (E5455-E5462) 1 DOI: 10.1073/pnas.1414221111)

Anang A. Shelat, Zheng Wang, Jeremy A. Horst, 2015 .

Structure-based lead optimization to improve antiviral potency and ADMET properties of phenyl-1H-pyrrole-carboxamide entry inhibitors targeted to HIV-1 gp120.

A. Debnath, L. Iyer, Y. Kwon, 2018, European journal of medicinal chemistry.