R. Dally

发表

Discovery of N-(6-Fluoro-1-oxo-1,2-dihydroisoquinolin-7-yl)-5-[(3R)-3-hydroxypyrrolidin-1-yl]thiophene-2-sulfonamide (LSN 3213128), a Potent and Selective Nonclassical Antifolate Aminoimidazole-4-carboxamide Ribonucleotide Formyltransferase (AICARFT) Inhibitor Effective at Tumor Suppression in a Can

Brandon J. Margolis, S. Atwell, Matthew R. Lee, 2017, Journal of Medicinal Chemistry.

Utilizing 19F NMR to investigate drug disposition early in drug discovery

Y. Hui, P. Kulanthaivel, P. Yi, 2015, Xenobiotica; the fate of foreign compounds in biological systems.

A selective estrogen receptor modulator designed for the treatment of uterine leiomyoma with unique tissue specificity for uterus and ovaries in rats.

A. Geiser, J. Dodge, H. Bryant, 2005, Journal of medicinal chemistry.

p38 kinase inhibitors for the treatment of arthritis and osteoporosis: thienyl, furyl, and pyrrolyl ureas.

J. S. Johnson, S. Wilhelm, W. Scott, 2001, Bioorganic & Medicinal Chemistry Letters.

Discovery of heterocyclic ureas as a new class of raf kinase inhibitors: identification of a second generation lead by a combinatorial chemistry approach.

J. S. Johnson, H. Wild, D. Rogers, 2001, Bioorganic & medicinal chemistry letters.

A fluorometric assay for HIV-protease activity using high-performance liquid chromatography.

J. Elting, M. Kamarck, J. Letsinger, 1990, Analytical biochemistry.

Imidazolyl benzimidazoles and imidazo[4,5-b]pyridines as potent p38alpha MAP kinase inhibitors with excellent in vivo antiinflammatory properties.

R. Campbell, Carlos Jaramillo, B. Anderson, 2008, Bioorganic & medicinal chemistry letters.

Isolation, identification and synthesis of an endogenous arachidonic amide that inhibits calcium channel antagonist 1,4-dihydropyridine binding.

S. Heald, D. Johnson, R. Janis, 1993, Prostaglandins, leukotrienes, and essential fatty acids.

Specific, high-affinity bradykinin binding by purified porcine kidney post-proline cleaving enzyme.

K. Georgiadis, C. Odya, R. Dally, 1987, Biochemical pharmacology.

Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models

P. Iversen, Y. Qian, Matthew R. Lee, 2018, Scientific Reports.

Structure-activity relationships of SERMs optimized for uterine antagonism and ovarian safety.

Daniel G Rudmann, A. Geiser, J. Dodge, 2007, Bioorganic & medicinal chemistry letters.

Optimization of Hydroxyethylamine Transition State Isosteres as Aspartic Protease Inhibitors by Exploiting Conformational Preferences.

J. F. Soriano, D. Timm, H. Broughton, 2017, Journal of medicinal chemistry.

Characterization of a novel AICARFT inhibitor which potently elevates ZMP and has anti-tumor activity in murine models

P. Iversen, Y. Qian, Matthew R. Lee, 2018, Scientific Reports.

Utilizing 19F NMR to investigate drug disposition early in drug discovery

Y. Hui, P. Kulanthaivel, P. Yi, 2015, Xenobiotica; the fate of foreign compounds in biological systems.