J. Couturier

Interaction of Double-stranded RNA-dependent Protein Kinase (PKR) with the Death Receptor Signaling Pathway in Amyloid β (Aβ)-treated Cells and in APPSLPS1 Knock-in Mice*

M. Paccalin, R. Pontcharraud, B. Fauconneau, 2009, The Journal of Biological Chemistry.

Pharmacological inhibition of PKR in APPswePS1dE9 mice transiently prevents inflammation at 12 months of age but increases Aβ42 levels in the late stages of the Alzheimer's disease.

M. Paccalin, R. Pontcharraud, B. Fauconneau, 2012, Current Alzheimer research.

Aggregated Tau activates NLRP3–ASC inflammasome exacerbating exogenously seeded and non-exogenously seeded Tau pathology in vivo

I. Dewachter, B. Brône, F. Huaux, 2019, Acta Neuropathologica.

PKR, the double stranded RNA-dependent protein kinase as a critical target in Alzheimer's disease

M. Paccalin, G. Page, C. Lafay-Chebassier, 2009, Journal of cellular and molecular medicine.

Evidence of molecular links between PKR and mTOR signalling pathways in Aβ neurotoxicity: Role of p53, Redd1 and TSC2

M. Paccalin, R. Pontcharraud, B. Fauconneau, 2009, Neurobiology of Disease.

Inhibition of double-stranded RNA-dependent protein kinase strongly decreases cytokine production and release in peripheral blood mononuclear cells from patients with Alzheimer's disease.

M. Paccalin, R. Pontcharraud, B. Fauconneau, 2010, Journal of Alzheimer's disease : JAD.

Tauopathy contributes to synaptic and cognitive deficits in a murine model for Alzheimer's disease

L. Goeminne, I. Dewachter, V. Laporte, 2014, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Activation of phagocytic activity in astrocytes by reduced expression of the inflammasome component ASC and its implication in a mouse model of Alzheimer disease

I. Dewachter, F. Huaux, J. Octave, 2016, Journal of Neuroinflammation.

Prevention of the β-amyloid peptide-induced inflammatory process by inhibition of double-stranded RNA-dependent protein kinase in primary murine mixed co-cultures

F. Terro, M. Paccalin, R. Pontcharraud, 2011, Journal of Neuroinflammation.