P. Arjunan

发表

A multipronged approach unravels unprecedented protein–protein interactions in the human 2-oxoglutarate dehydrogenase multienzyme complex

F. Jordan, Olivér Ozohanics, W. Furey, 2018, The Journal of Biological Chemistry.

Pyruvate dehydrogenase complex deficiency is linked to regulatory loop disorder in the αV138M variant of human pyruvate dehydrogenase

M. J. Whitley, F. Jordan, Yun-Hee Park, 2018, The Journal of Biological Chemistry.

Structure-function relationships and flexible tetramer assembly in pyruvate decarboxylase revealed by analysis of crystal structures.

F. Jordan, W. Furey, M. Sax, 1998, Biochimica et biophysica acta.

Communication between Thiamin Cofactors in the Escherichia coli Pyruvate Dehydrogenase Complex E1 Component Active Centers

K. Tittmann, F. Jordan, W. Furey, 2010, The Journal of Biological Chemistry.

Glutamate 636 of the Escherichia coli Pyruvate Dehydrogenase-E1 Participates in Active Center Communication and Behaves as an Engineered Acetolactate Synthase with Unusual Stereoselectivity*

K. Tittmann, F. Jordan, W. Furey, 2005, Journal of Biological Chemistry.

Novel Binding Motif and New Flexibility Revealed by Structural Analyses of a Pyruvate Dehydrogenase-Dihydrolipoyl Acetyltransferase Subcomplex from the Escherichia coli Pyruvate Dehydrogenase Multienzyme Complex*

F. Jordan, W. Furey, G. Calero, 2014, The Journal of Biological Chemistry.

Inhibition of the Escherichia coli Pyruvate Dehydrogenase Complex E1 Subunit and Its Tyrosine 177 Variants by Thiamin 2-Thiazolone and Thiamin 2-Thiothiazolone Diphosphates

Frank Jordan, William Furey, Zhen Zhang, 2001, The Journal of Biological Chemistry.

Crystal structure of the thiamin diphosphate-dependent enzyme pyruvate decarboxylase from the yeast Saccharomyces cerevisiae at 2.3 A resolution.

W Furey, S. Swaminathan, F. Dyda, 1995, Journal of molecular biology.

Dual catalytic apparatus of the thiamin diphosphate coenzyme: acid-base via the 1',4'-iminopyrimidine tautomer along with its electrophilic role.

Frank Jordan, William Furey, F. Jordan, 2003, Journal of the American Chemical Society.

A Thiamin-bound, Pre-decarboxylation Reaction Intermediate Analogue in the Pyruvate Dehydrogenase E1 Subunit Induces Large Scale Disorder-to-Order Transformations in the Enzyme and Reveals Novel Structural Features in the Covalently Bound Adduct*

F. Jordan, W. Furey, M. Sax, 2006, Journal of Biological Chemistry.

Structure of the pyruvate dehydrogenase multienzyme complex E1 component from Escherichia coli at 1.85 A resolution.

J. Guest, F. Jordan, W. Furey, 2002, Biochemistry.

Direct Pore Binding as a Mechanism for Isoflurane Inhibition of the Pentameric Ligand-gated Ion Channel ELIC

A. Cohen, Yan Xu, P. Tang, 2015, Scientific Reports.

Crystal structure of the disease-causing G194C mutant of the human dihydrolipoamide dehydrogenase

M. Weiss, B. Nagy, F. Jordan, 2019 .

Structure and Function of the Catalytic Domain of the Dihydrolipoyl Acetyltransferase Component in Escherichia coli Pyruvate Dehydrogenase Complex*

F. Jordan, W. Furey, G. Calero, 2014, The Journal of Biological Chemistry.

Insight to the Interaction of the Dihydrolipoamide Acetyltransferase (E2) Core with the Peripheral Components in the Escherichia coli Pyruvate Dehydrogenase Complex via Multifaceted Structural Approaches*

F. Jordan, Yun-Hee Park, W. Furey, 2013, The Journal of Biological Chemistry.

Yeast Pyruvate Decarboxylase: New Features of the Structure and Mechanism

E. Sergienko, F. Jordan, W. Furey, 2003 .

A Dynamic Loop at the Active Center of the Escherichia coli Pyruvate Dehydrogenase Complex E1 Component Modulates Substrate Utilization and Chemical Communication with the E2 Component*

Frank Jordan, William Furey, F. Jordan, 2007, Journal of Biological Chemistry.

Structural basis of neurosteroid anesthetic action on GABAA receptors

A. Cohen, T. Tillman, Yan Xu, 2018, Nature Communications.

Structure and Intersubunit Information Transfer in the E. coli Pyruvate Dehydrogenase Multienzyme Complex

S. Zhang, F. Jordan, W. Furey, 2003 .

Underlying molecular alterations in human dihydrolipoamide dehydrogenase deficiency revealed by structural analyses of disease-causing enzyme variants.

M. Weiss, B. Nagy, F. Jordan, 2019, Human molecular genetics.

Active-site changes in the pyruvate dehydrogenase multienzyme complex E1 apoenzyme component from Escherichia coli observed at 2.32 A resolution.

F. Jordan, W. Furey, M. Sax, 2006, Acta crystallographica. Section D, Biological crystallography.

Multiple roles of mobile active center loops in the E1 component of the Escherichia coli pyruvate dehydrogenase complex - Linkage of protein dynamics to catalysis.

F. Jordan, W. Furey, N. Nemeria, 2009, Journal of molecular catalysis. B, Enzymatic.