C. Bottema

发表

Role of sterol structure in the thermotropic behavior of plasma membranes of Saccharomyces cerevisiae

L. W. Parks, C. Bottema, C. McLean-Bowen, 1983 .

Nucleic Acids Research

R. Ketterling, C. Bottema, H. I. Chol, 2017, Nucleic acids research.

Δ14-sterol reductase in Saccharomyces cerevisiae

L. W. Parks, C. Bottema, 1978 .

Delta14-sterol reductase in Saccharomyces cerevisiae.

L. W. Parks, C. Bottema, 1978, Biochimica et biophysica acta.

Aspects of sterol metabolism in the yeastSaccharomyces cerevisiae and inPhytophthora

L. W. Parks, R. Gonzales, F. Taylor, 1982, Lipids.

DIRECT CARRIER TESTING IN 14 FAMILIES WITH HAEMOPHILIA B

D. Koeberl, S. Sommer, C. Bottema, 1989, The Lancet.

T296→M, a common mutation causing mild hemophilia B in the Amish and others: founder effect, variability in factor IX activity assays, and rapid carrier detection

S. Sommer, D. Koeberl, R. Ketterling, 1991, Human Genetics.

Sterol analysis of the inner and outer mitochondrial membranes in yeast

L. W. Parks, C. Bottema, 1980, Lipids.

A past mutation at Isoleucine397 is now a common cause of moderate/mild haemophilia B

D. Koeberl, A. Shapiro, D. Lillicrap, 1990, British journal of haematology.

25 – DIRECT SEQUENCING WITH THE AID OF PHAGE PROMOTERS

J. Buerstedde, D. Koeberl, G. Sarkar, 1990 .

Alu repeats in the human factor IX gene: The rate of polymorphism is not substantially elevated

C. Dutton, S. Sommer, C. Bottema, 1993, Human mutation.

Missense mutations and the magnitude of functional deficit: the example of factor IX

S. Sommer, R. Ketterling, E. Bowie, 1992, Human Genetics.

The pattern of spontaneous germ-line mutation: relative rates of mutation at or near CpG dinucleotides in the factor IX gene

B. Gostout, A. Shapiro, R. Ketterling, 1993, Human Genetics.

Recurrent nonsense mutations at arginine residues cause severe hemophilia B in unrelated hemophiliacs

S. Sommer, C. Bottema, D. Koeberl, 1990, Human Genetics.

Rate of PoIynRorphism Is Not Substantially Elevated

C. Dutton, S. Sommer, C. Bottema, 2005 .

Multiple functions for sterols in Saccharomyces cerevisiae.

L. W. Parks, C. Bottema, C. Bottema, 1985, Biochimica et Biophysica Acta.

Functionally important regions of the factor IX gene have a low rate of polymorphism and a high rate of mutation in the dinucleotide CpG.

J. Buerstedde, C. Bottema, D. Koeberl, 1989, American journal of human genetics.

Why does the human factor IX gene have a G + C content of 40%?

S. Sommer, C. Bottema, R. Ketterling, 1991, American journal of human genetics.

PCR amplification of specific alleles: rapid detection of known mutations and polymorphisms.

C. Bottema, S. Sommer, S. Sommer, 1993, Mutation research.

A novel method for detecting point mutations or polymorphisms and its application to population screening for carriers of phenylketonuria.

C. Bottema, S. Sommer, J. Sobell, 1989, Mayo Clinic proceedings.

Missense mutations and evolutionary conservation of amino acids: evidence that many of the amino acids in factor IX function as "spacer" elements.

S S Sommer, S. Sommer, C. Bottema, 1991, American journal of human genetics.

PCR amplification of specific alleles (PASA) is a general method for rapidly detecting known single-base changes.

C. Bottema, S. Sommer, S S Sommer, 1992, BioTechniques.

Germ-line origins of mutation in families with hemophilia B: the sex ratio varies with the type of mutation.

D. Schaid, S. Sommer, C. Bottema, 1993, American journal of human genetics.

Evidence that descendants of three founders constitute about 25% of hemophilia B in the United States.

S. Sommer, C. Bottema, R. Ketterling, 1991, Genomics.

Polymerase chain reaction amplification of specific alleles: a general method of detection of mutations, polymorphisms, and haplotypes.

C. Bottema, G. Sarkar, S. Sommer, 1993, Methods in Enzymology.