Katie E Copley

NUP62 localizes to ALS/FTLD pathological assemblies and contributes to TDP-43 insolubility

Eric N. Anderson, E. Kiskinis, U. Pandey, 2022, Nature Communications.

Nup62 is recruited to pathological condensates and promotes TDP-43 insolubility in C9orf72 and sporadic ALS/FTLD.

E. Kiskinis, U. Pandey, J. Kofler, 2021 .

TDP-43 condensation properties specify its RNA-binding and regulatory repertoire

Nicolas L. Fawzi, J. Ule, N. Luscombe, 2021, Cell.

Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation.

J. Shorter, Y. Goldman, Huiqing Shen, 2022, Molecular cell.

RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43

B. Portz, Lin Guo, J. Shorter, 2019, Neuron.