J. Ledo

发表

Lack of a site-specific phosphorylation of Presenilin 1 disrupts microglial gene networks and progenitors during development

P. Greengard, O. Troyanskaya, Ran Zhang, 2020, PloS one.

Memantine Rescues Transient Cognitive Impairment Caused by High-Molecular-Weight Aβ Oligomers But Not the Persistent Impairment Induced by Low-Molecular-Weight Oligomers

W. Klein, S. Ferreira, J. Clarke, 2013, The Journal of Neuroscience.

A Developmental Role for Microglial Presenilin 1 in Memory

P. Greengard, J. Friedman, B. Stevens, 2021, bioRxiv.

Activated microglia mediate synapse loss and short-term memory deficits in a mouse model of transthyretin-related oculoleptomeningeal amyloidosis

D. Foguel, F. Gomes, S. Ferreira, 2013, Cell Death and Disease.

Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice

D. Foguel, S. Ferreira, J. Clarke, 2012, Molecular Psychiatry.

Targeting Alzheimer's Pathology through PPARγ Signaling: Modulation of Microglial Function

M. Lourenco, Mychael V. Lourenco, J. Ledo, 2013, The Journal of Neuroscience.

Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation

D. Munoz, J. Carvalheira, W. Klein, 2015, EMBO molecular medicine.

Amyloidogenic and anti-amyloidogenic properties of presenilin 1.

M. Pulina, Victor H. Bustos, J. Ledo, 2021, Advances in pharmacology.

Interaction of amyloid-β (Aβ) oligomers with neurexin 2α and neuroligin 1 mediates synapse damage and memory loss in mice

F. Gomes, S. Ferreira, J. Clarke, 2017, The Journal of Biological Chemistry.

Molecular and Cellular Adaptations in Hippocampal Parvalbumin Neurons Mediate Behavioral Responses to Chronic Social Stress

W. Wang, Dionnet L. Bhatti, E. Azevedo, 2021, bioRxiv.

Presenilin 1 phosphorylation regulates amyloid-β degradation by microglia

P. Greengard, O. Troyanskaya, Thomas Liebmann, 2020, Molecular Psychiatry.

Prion Protein Modulates Monoaminergic Systems and Depressive-like Behavior in Mice*

R. Linden, Danielle Beckman, L. E. Santos, 2015, The Journal of Biological Chemistry.

Palmitate Is Increased in the Cerebrospinal Fluid of Humans with Obesity and Induces Memory Impairment in Mice via Pro-inflammatory TNF-α.

J. Delgado-García, A. Gruart, L. Velloso, 2020, Cell reports.

Neurexin 2 and neuroligin 1 mediate synaptic impact of A Os ? ? ? ? ? ?

F. Gomes, S. Ferreira, J. Clarke, 2017 .

Cross Talk Between Brain Innate Immunity and Serotonin Signaling Underlies Depressive-Like Behavior Induced by Alzheimer's Amyloid-β Oligomers in Mice

L. Velloso, D. Foguel, A. Teixeira, 2016, The Journal of Neuroscience.

Reply to Altered Monoaminergic Systems and Depressive-like Behavior in Congenic Prion Protein Knock-out Mice

R. Linden, Danielle Beckman, L. E. Santos, 2015, Journal of Biological Chemistry.