Douglas L. Orsi

发表

Cobalt-Catalyzed Selective Unsymmetrical Dioxidation of gem-Difluoroalkenes.

J. Douglas, Ryan A. Altman, Jacob P. Sorrentino, 2020, The Journal of organic chemistry.

Cu(II)-Catalyzed Unsymmetrical Dioxidation of gem-Difluoroalkenes to Generate α,α-Difluorinated-α-phenoxyketones.

M. Yadav, Suvajit Koley, Ryan A. Altman, 2022, The Journal of organic chemistry.

Exploiting the unusual effects of fluorine in methodology.

Ryan A. Altman, Douglas L. Orsi, 2017, Chemical communications.

Discovery of a potent M5 antagonist with improved clearance profile. Part 1: piperidine amide-based antagonists.

Andrew S. Felts, Anna L. Blobaum, C. Lindsley, 2022, Bioorganic & medicinal chemistry letters.

Base Catalysis Enables Access to α,α-Difluoroalkylthioethers.

Ryan A. Altman, Douglas L. Orsi, B. J. Easley, 2017, Organic letters.

Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069

Lindsay C. Westlake, M. Meyerson, A. Cherniack, 2022, Journal of medicinal chemistry.

Development of VU6019650: A Potent, Highly Selective, and Systemically Active Orthosteric Antagonist of the M5 Muscarinic Acetylcholine Receptor for the Treatment of Opioid Use Disorder.

Andrew S. Felts, Anna L. Blobaum, N. Schnetz-Boutaud, 2022, Journal of medicinal chemistry.

Acid-Catalyzed Hydrothiolation of gem-Difluorostyrenes to Access α,α-Difluoroalkylthioethers.

Ryan A. Altman, Jacob P. Sorrentino, Douglas L. Orsi, 2021, The Journal of organic chemistry.

BBDFA: A Practical Reagent for Trifluoromethylation of Allylic and Benzylic Alcohols on Preparative Scale

F. Gosselin, Ryan A. Altman, S. Kelly, 2019, Organic Process Research & Development.

Ligand-controlled regiodivergent palladium-catalyzed decarboxylative allylation reaction to access α,α-difluoroketones.

Ryan A. Altman, Douglas L. Orsi, Ming-Hsiu Yang, 2015, Angewandte Chemie.

Organocatalytic Strategy for Hydrophenolation of Gem-Difluoroalkenes.

M. Yadav, Ryan A. Altman, Douglas L. Orsi, 2019, Tetrahedron.

Bioorthogonal prodrug activation driven by a strain-promoted 1,3-dipolar cycloaddition

V. Staudacher, Jiayi Chen, A. Gamble, 2014, Chemical science.

Cu(II) Catalyzed Unsymmetrical Di-oxidation of gem-Difluoroalkenes to Generate α,α-Difluorinated-α-Phenoxyketones, an Unstudied Substructure

M. Yadav, Suvajit Koley, Ryan A. Altman, 2021 .

Exploiting the unusual effects of fluorine in methodology.

Ryan A. Altman, Douglas L. Orsi, 2017, Chemical communications.

Ligand-controlled regiodivergent palladium-catalyzed decarboxylative allylation reaction to access α,α-difluoroketones.

Ryan A. Altman, Douglas L. Orsi, Ming-Hsiu Yang, 2015, Angewandte Chemie.

Correction to “Discovery and Structure-Based Design of Potent Covalent PPARγ Inverse-Agonists BAY-4931 and BAY-0069”

Lindsay C. Westlake, M. Meyerson, A. Cherniack, 2022, Journal of medicinal chemistry.

Discovery and characterization of orally bioavailable 4-chloro-6-fluoroisophthalamides as covalent PPARG inverse-agonists.

P. Lienau, E. Pook, Jonathan T. Goldstein, 2022, Bioorganic & medicinal chemistry.