Hamilton B. Bennett

Isosteric replacements of the carboxylic acid of drug candidate VX-787: Effect of charge on antiviral potency and kinase activity of azaindole-based influenza PB2 inhibitors.

P. Charifson, Tiansheng Wang, E. Perola, 2015, Bioorganic & medicinal chemistry letters.

Novel Ranking System for Identifying Efficacious Anti-Influenza Virus PB2 Inhibitors

P. Charifson, Steven J M Jones, Alice Tsai, 2015, Antimicrobial Agents and Chemotherapy.

Discovery of Novel, Orally Bioavailable β-Amino Acid Azaindole Inhibitors of Influenza PB2.

P. Charifson, Alice Tsai, Tiansheng Wang, 2017, ACS medicinal chemistry letters.

Novel 2-Substituted 7-Azaindole and 7-Azaindazole Analogues as Potential Antiviral Agents for the Treatment of Influenza.

F. Maltais, P. Charifson, Alice Tsai, 2017, ACS medicinal chemistry letters.

Preclinical Activity of VX-787, a First-in-Class, Orally Bioavailable Inhibitor of the Influenza Virus Polymerase PB2 Subunit

M. Murcko, P. Charifson, A. Kwong, 2014, Antimicrobial Agents and Chemotherapy.

Discovery of a novel, first-in-class, orally bioavailable azaindole inhibitor (VX-787) of influenza PB2.

M. Murcko, F. Maltais, P. Charifson, 2014, Journal of medicinal chemistry.

Novel 2-Substituted 7-Azaindole and 7-Azaindazole Analogues as Potential Antiviral Agents for the Treatment of Influenza.

F. Maltais, P. Charifson, Alice Tsai, 2017, ACS medicinal chemistry letters.

Discovery of a novel, first-in-class, orally bioavailable azaindole inhibitor (VX-787) of influenza PB2.

M. Murcko, F. Maltais, P. Charifson, 2014, Journal of medicinal chemistry.