Rongxing Liu

Cisplatin causes covalent inhibition of protein-tyrosine phosphatase 1B (PTP1B) through reaction with its active site cysteine: Molecular, cellular and in vivo mice studies.

G. Moroy, J. Dupret, F. Deshayes, 2022, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Biochemical, Enzymatic, and Computational Characterization of Recurrent Somatic Mutations of the Human Protein Tyrosine Phosphatase PTP1B in Primary Mediastinal B Cell Lymphoma

Ximing Xu, J. Dupret, F. Deshayes, 2022, International journal of molecular sciences.

Human Protein Tyrosine Phosphatase 1B (PTP1B): From Structure to Clinical Inhibitor Perspectives

J. Dupret, J. Berthelet, C. Mathieu, 2022, International journal of molecular sciences.

T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide

Ximing Xu, C. Chomienne, S. Ganesan, 2019, Molecular Pharmacology.

From transglutaminases (TGs) to arylamine N-acetyltransferases (NATs): Insight into the role of a spatially conserved aromatic amino acid position in the active site of these two families of enzymes.

A. Chaffotte, Ximing Xu, J. Dupret, 2020, Biochemical and biophysical research communications.

Human CREBBP acetyltransferase is impaired by etoposide quinone, an oxidative and leukemogenic metabolite of the anticancer drug etoposide through modification of redox-sensitive zinc-finger cysteine residues.

C. Chomienne, J. Dupret, F. Guidez, 2020, Free radical biology & medicine.

Structural characterization of a pathogenic mutant of human protein tyrosine phosphatase PTPN2 (Cys216Gly) that causes very early onset autoimmune enteropathy

A. Mechaly, A. Haouz, N. Cerf-Bensussan, 2021, Protein science : a publication of the Protein Society.