Fernando Rodrigues Lima

Biochemical, Enzymatic, and Computational Characterization of Recurrent Somatic Mutations of the Human Protein Tyrosine Phosphatase PTP1B in Primary Mediastinal B Cell Lymphoma

Ximing Xu, J. Dupret, F. Deshayes, 2022, International journal of molecular sciences.

Human Protein Tyrosine Phosphatase 1B (PTP1B): From Structure to Clinical Inhibitor Perspectives

J. Dupret, J. Berthelet, C. Mathieu, 2022, International journal of molecular sciences.

T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug Etoposide

Ximing Xu, C. Chomienne, S. Ganesan, 2019, Molecular Pharmacology.

The structure of brain glycogen phosphorylase—from allosteric regulation mechanisms to clinical perspectives

J. Dupret, C. Mathieu, Fernando Rodrigues Lima, 2017, The FEBS journal.

Human CREBBP acetyltransferase is impaired by etoposide quinone, an oxidative and leukemogenic metabolite of the anticancer drug etoposide through modification of redox-sensitive zinc-finger cysteine residues.

C. Chomienne, J. Dupret, F. Guidez, 2020, Free radical biology & medicine.

Structural characterization of a pathogenic mutant of human protein tyrosine phosphatase PTPN2 (Cys216Gly) that causes very early onset autoimmune enteropathy

A. Mechaly, A. Haouz, N. Cerf-Bensussan, 2021, Protein science : a publication of the Protein Society.

Targeting neutrophil extracellular traps: A novel strategy in hematologic malignancies.

Fernando Rodrigues Lima, Qing Nian, Rongxing Liu, 2024, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

U2AF1 in various neoplastic diseases and relevant targeted therapies for malignant cancers with complex mutations (Review)

Fernando Rodrigues Lima, Qing Nian, Rongxing Liu, 2023, Oncology reports.

Haploinsufficiency in PTPN2 leads to early-onset systemic autoimmunity from Evans syndrome to lupus.

F. Rieux-Laucat, N. Aladjidi, M. Malphettes, 2024, The Journal of experimental medicine.