Linda G. Otterson

In Vitro Antibacterial Activity of AZD0914, a New Spiropyrimidinetrione DNA Gyrase/Topoisomerase Inhibitor with Potent Activity against Gram-Positive, Fastidious Gram-Negative, and Atypical Bacteria

G. Basarab, M. Huband, P. Miller, 2014, Antimicrobial Agents and Chemotherapy.

Characterization of the Novel DNA Gyrase Inhibitor AZD0914: Low Resistance Potential and Lack of Cross-Resistance in Neisseria gonorrhoeae

M. Huband, R. Alm, R. Mclaughlin, 2014, Antimicrobial Agents and Chemotherapy.

Pseudomonas aeruginosa Bacteremic Patients Exhibit Nonprotective Antibody Titers Against Therapeutic Antibody Targets PcrV and Psl Exopolysaccharide.

J. Thaden, N. Shire, V. Fowler, 2016, The Journal of infectious diseases.

Discovery of Novel DNA Gyrase Inhibiting Spiropyrimidinetriones: Benzisoxazole Fusion with N-Linked Oxazolidinone Substituents Leading to a Clinical Candidate (ETX0914).

M. Gowravaram, G. Basarab, V. Galullo, 2015, Journal of medicinal chemistry.

Characterization of the novel DNA gyrase inhibitor AZD 0914 : Low resistance potential 1 and lack of cross-resistance in Neisseria gonorrhoeae . 2 3 4 5 6

M. Huband, R. Alm, James D. Whiteaker, 2014 .

In vivo validation of thymidylate kinase (TMK) with a rationally designed, selective antibacterial compound.

Diane Joseph-McCarthy, Sameer Kawatkar, D. Joseph-McCarthy, 2012, ACS chemical biology.

Antibacterial inhibitors of Gram-positive thymidylate kinase: structure-activity relationships and chiral preference of a new hydrophobic binding region.

T. Keating, Gabriel Martínez-Botella, John N Breen, 2014, Journal of medicinal chemistry.

Discovery of selective and potent inhibitors of gram-positive bacterial thymidylate kinase (TMK).

Diane Joseph-McCarthy, Jon Read, Sameer Kawatkar, 2012, Journal of medicinal chemistry.