M. Valecha

发表

BRCA1 represses DNA replication initiation through antagonizing estrogen signaling and maintains genome stability in parallel with WEE1‐MCM2 signaling during pregnancy

C. Deng, M. Aladjem, Xiaoling Xu, 2018, Human molecular genetics.

Single-cell phylogenies reveal deviations from clock-like, neutral evolution in cancer and healthy tissues

N. Beerenwinkel, D. Posada, J. Kuipers, 2022, bioRxiv.

Somatic variant calling from single-cell DNA sequencing data

David Posada, M. Valecha, Monica Valecha, 2022, Computational and structural biotechnology journal.

Comparative analysis of capture methods for genomic profiling of circulating tumor cells in colorectal cancer

D. Posada, J. Cubiella, R. Piñeiro, 2022, medRxiv.

NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation

Zhengqiang Miao, Jiaolin Bao, Xiaoling Xu, 2020, Nature Communications.

Clonality and timing of relapsing colorectal cancer metastasis revealed through whole-genome single-cell sequencing

D. Posada, I. Sauer, C. Sers, 2022, medRxiv.

SIEVE: joint inference of single-nucleotide variants and cell phylogeny from single-cell DNA sequencing data

N. Beerenwinkel, D. Posada, J. Kuipers, 2022, bioRxiv.

Phylovar: Towards scalable phylogeny-aware inference of single-nucleotide variations from single-cell DNA sequencing data

Huw A. Ogilvie, L. Nakhleh, D. Posada, 2022, bioRxiv.

Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics

Ping Chen, Jiaolin Bao, Wenhui Hao, 2021, Nature Communications.

NOTCH1 activation compensates BRCA1 deficiency and promotes triple-negative breast cancer formation

C. Deng, Zhengqiang Miao, Jiaolin Bao, 2020, Nature Communications.

SB Digestor: a tailored driver gene identification tool for dissecting heterogeneous Sleeping Beauty transposon-induced tumors

Zhengqiang Miao, Peng Hu, Chuxia Deng, 2023, International journal of biological sciences.

Single-cell mtDNA heteroplasmy in colorectal cancer

D. Posada, A. Pérez-Figueroa, J. Cameselle-Teijeiro, 2021, medRxiv.

Single-cell phylogenies reveal changes in the evolutionary rate within cancer and healthy tissues

N. Beerenwinkel, D. Posada, J. Kuipers, 2023, Cell genomics.

DelSIEVE: joint inference of single-nucleotide variants, somatic deletions, and cell phylogeny from single-cell DNA sequencing data

N. Beerenwinkel, J. Kuipers, E. Szczurek, 2023, bioRxiv.