Paul D. Lira

发表

Piperazinyl CCR1 antagonists--optimization of human liver microsome stability.

Christopher S. Poss, M. Hayward, J. Driscoll, 2007, Bioorganic & medicinal chemistry letters.

Novel CCR1 antagonists with improved metabolic stability.

Christopher S. Poss, J. Kath, W. Brissette, 2004, Bioorganic & medicinal chemistry letters.

CP-481,715, a Potent and Selective CCR1 Antagonist with Potential Therapeutic Implications for Inflammatory Diseases*

Christopher S. Poss, J. Kath, W. Brissette, 2003, Journal of Biological Chemistry.

Potent small molecule CCR1 antagonists.

Christopher S. Poss, J. Kath, W. Brissette, 2004, Bioorganic & medicinal chemistry letters.

Targeting of 4-1BB by monoclonal antibody PF-05082566 enhances T-cell function and promotes anti-tumor activity

S. Bergqvist, R. Doyonnas, T. Fisher, 2012, Cancer Immunology, Immunotherapy.

Thrombopoietin receptor activation: transmembrane helix dimerization, rotation, and allosteric modulation

D. Engelman, J. Rogers, L. Gotow, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

The identification of orally bioavailable thrombopoietin agonists.

A. Marfat, M. Munchhof, T. Harris, 2009, Bioorganic & medicinal chemistry letters.

Pyrimidine benzamide-based thrombopoietin receptor agonists.

M. Munchhof, J. Driscoll, Jonathan L. Doty, 2007, Bioorganic & medicinal chemistry letters.

Analysis of the role of the HIF hydroxylase family members in erythropoiesis.

J. Stock, W. Brissette, D. Perregaux, 2009, Biochemical and biophysical research communications.

Multiplexed deep sequencing analysis of ALK kinase domain identifies resistance mutations in relapsed patients following crizotinib treatment.

Shibing Deng, J. Christensen, J. Ahn, 2013, Genomics.

Abstract 1958: Interrogating hedgehog pathway and smoothened inhibition by PF-04449913 in patient-derived acute myeloid leukemia models

Shibing Deng, C. Heinlein, Xianxian Zheng, 2014 .

Abstract 3713: Identifying a mechanism of acquired resistance to the combined inhibition of PI3K/mTOR and MEK in colorectal carcinoma

J. Christensen, T. Vanarsdale, V. Fantin, 2014 .

Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice.

A. Rudensky, J. Stock, J. Mcneish, 1999, Immunity.

A Phase 1 study of the novel gamma-secretase inhibitor PF-03084014 in patients with T-cell acute lymphoblastic leukemia and T-cell lymphoblastic lymphoma

F. Kuo, J. Aster, G. Garcia-Manero, 2015, Blood Cancer Journal.

Genomic organization of the CC chemokine mip-3alpha/CCL20/larc/exodus/SCYA20, showing gene structure, splice variants, and chromosome localization.

S. McColl, J. Boyd, Ranjeny Thomas, 2001, Genomics.

Genomic organization and biological characterization of the novel human CC chemokine DC-CK-1/PARC/MIP-4/SCYA18.

S. McColl, W. Brissette, K. Neote, 1999, Genomics.