Kristen A Trevena

Piperazinyl CCR1 antagonists--optimization of human liver microsome stability.

Christopher S. Poss, M. Hayward, J. Driscoll, 2007, Bioorganic & medicinal chemistry letters.

Optimization of the physicochemical and pharmacokinetic attributes in a 6-azauracil series of P2X7 receptor antagonists leading to the discovery of the clinical candidate CE-224,535.

A. Kalgutkar, C. Gabel, R. Shepard, 2011, Bioorganic & medicinal chemistry letters.

A rational chemical intervention strategy to circumvent bioactivation liabilities associated with a nonpeptidyl thrombopoietin receptor agonist containing a 2-amino-4-arylthiazole motif.

G. S. Walker, A. Kalgutkar, A. Mutlib, 2007, Chemical research in toxicology.

Structure-activity relationships and hepatic safety risks of thiazole agonists of the thrombopoietin receptor.

M. Munchhof, T. Harris, J. Driscoll, 2010, Bioorganic & medicinal chemistry letters.

The identification of orally bioavailable thrombopoietin agonists.

A. Marfat, M. Munchhof, T. Harris, 2009, Bioorganic & medicinal chemistry letters.

Pyrimidine benzamide-based thrombopoietin receptor agonists.

M. Munchhof, J. Driscoll, Jonathan L. Doty, 2007, Bioorganic & medicinal chemistry letters.

Use of Immortalized Human Hepatocytes to Predict the Magnitude of Clinical Drug-Drug Interactions Caused by CYP3A4 Induction

T. Maurer, S. D. de Morais, O. Fahmi, 2006, Drug Metabolism and Disposition.