P. H. Bos

发表

Combining Cloud-Based Free-Energy Calculations, Synthetically Aware Enumerations, and Goal-Directed Generative Machine Learning for Rapid Large-Scale Chemical Exploration and Optimization

Phani Ghanakota, Robert Abel, K. Leswing, 2020, J. Chem. Inf. Model..

K-RasG12D has an allosteric small molecule binding site

B. Stockwell, J. Chambers, Huizhong Feng, 2021 .

Cu-catalyzed enantioselective allylic alkylation with organolithium reagents

B. Feringa, M. Perez, S. Harutyunyan, 2017, Nature Protocols.

Reaction-Based Enumeration, Active Learning, and Free Energy Calculations To Rapidly Explore Synthetically Tractable Chemical Space and Optimize Potency of Cyclin-Dependent Kinase 2 Inhibitors

Markus K. Dahlgren, Ivan Tubert Brohman, A. Bortolato, 2019, J. Chem. Inf. Model..

Catalytic asymmetric conjugate addition/oxidative dearomatization towards multifunctional spirocyclic compounds.

B. Feringa, A. Minnaard, A. Rudolph, 2011, Angewandte Chemie.

Catalyst-controlled reverse selectivity in C-C bond formation: NHC-Cu-catalyzed α-selective allylic alkylation with organolithium reagents.

B. Feringa, Stefano F. Pizzolato, M. Fañanás‐Mastral, 2015, Chemical communications.

Asymmetric allylic alkylation of acyclic allylic ethers with organolithium reagents.

B. Feringa, M. Perez, S. Harutyunyan, 2012, Chemistry.

Enantioselective synthesis of tertiary and quaternary stereogenic centers: copper/phosphoramidite-catalyzed allylic alkylation with organolithium reagents.

B. Feringa, M. Perez, S. Harutyunyan, 2012, Angewandte Chemie.

Catalytic asymmetric carbon–carbon bond formation via allylic alkylations with organolithium compounds

B. Feringa, M. Perez, S. Harutyunyan, 2011, Nature Chemistry.

Catalytic asymmetric conjugate addition of dialkylzinc reagents to a,b-unsaturated sulfones†

P. H. Bos, 2010 .

Catalytic asymmetric conjugate addition of dialkylzinc reagents to alpha,beta-unsaturated sulfones.

B. Feringa, A. Minnaard, M. Fernández‐Ibáñez, 2010, Organic & biomolecular chemistry.

Catalytic asymmetric conjugate addition of grignard reagents to alpha,beta-unsaturated sulfones.

B. Feringa, A. Minnaard, P. H. Bos, 2008, Organic letters.

Copper-catalyzed asymmetric ring opening of oxabicyclic alkenes with organolithium reagents.

B. Feringa, M. Perez, S. Harutyunyan, 2012, Chemical communications.

Tandem dienone photorearrangement-cycloaddition for the rapid generation of molecular complexity.

J. Porco, C. Stephenson, P. H. Bos, 2013, Journal of the American Chemical Society.

Copper-Binding Small Molecule Induces Oxidative Stress and Cell-Cycle Arrest in Glioblastoma-Patient-Derived Cells.

B. Stockwell, D. Carpizo, N. Pagano, 2018, Cell chemical biology.

Novel asymmetric copper-catalysed transformations

B. Feringa, A. Minnaard, A. Rudolph, 2012 .

Synthetic Study toward Total Synthesis of (±)-Germine: Synthesis of (±)-4-Methylenegermine.

A. Clark, P. Parsons, M. Kitamura, 2017, Organic letters.

Stereoselective synthesis of 2,3,7-trimethylcyclooctanone and related compounds and determination of their relative and absolute configurations by the MalphaNP acid method.

N. Harada, B. Feringa, A. Minnaard, 2008, Chirality.

FINO2 Initiates Ferroptosis Through GPX4 Inactivation and Iron Oxidation

B. Stockwell, M. Shchepinov, Daniel W. Heindel, 2018, Nature Chemical Biology.

Multivalent Small-Molecule Pan-RAS Inhibitors

Matthew E. Welsch, A. Ferrando, B. Stockwell, 2017, Cell.

Multivalent Small-Molecule Pan-RAS Inhibitors Graphical

Matthew E. Welsch, A. Ferrando, B. Stockwell, 2017 .

Development of MAP4 Kinase Inhibitors as Motor Neuron-Protecting Agents.

H. Wichterle, B. Stockwell, A. Zask, 2019, Cell chemical biology.

K-RasG12D Has a Potential Allosteric Small Molecule Binding Site.

B. Stockwell, J. Chambers, Huizhong Feng, 2019, Biochemistry.

K‐Ras Has a Potential Allosteric Small Molecule Binding Site

B. Stockwell, J. Chambers, Huizhong Feng, 2019 .

AutoDesigner, a De Novo Design Algorithm for Rapidly Exploring Large Chemical Space for Lead Optimization: Application to the Design and Synthesis of d-Amino Acid Oxidase Inhibitors

Volker A. Eyrich, Robert Abel, Sathesh Bhat, 2022, J. Chem. Inf. Model..

University of Groningen Copper-catalyzed asymmetric ring opening of oxabicyclic alkenes with organolithium reagents

B. Feringa, M. Perez, S. Harutyunyan, 2011 .