L. Niv-Spector

发表

Mapping leptin-interacting sites in recombinant leptin-binding domain (LBD) subcloned from chicken leptin receptor.

J. Grosclaude, O. Livnah, E. Gussakovsky, 2005, The Biochemical journal.

Principles of strategic drug delivery to the brain (SDDB): Development of anorectic and orexigenic analogs of leptin

W. Banks, A. Kabanov, S. Vinogradov, 2011, Physiology & Behavior.

Pegylated leptin antagonist is a potent orexigenic agent: preparation and mechanism of activity.

Z. Halpern, E. Elinav, W. Banks, 2009, Endocrinology.

Is leptin an important physiological regulator of CRP?

S. Reicher, A. Gertler, L. Niv-Spector, 2007, Nature Medicine.

Pituitary and placental ovine growth hormone variants differ in their receptor-binding ability and in their biological properties.

E. Gootwine, S. Reicher, A. Gertler, 2008, General and comparative endocrinology.

Leptin signaling and apoptotic effects in human prostate cancer cell lines

A. Gertler, E. Weiss-Messer, M. Inbar, 2011, The Prostate.

The obese phenotype-inducing N82K mutation in human leptin disrupts receptor-binding and biological activity.

A. Gertler, Asaf Grupi, M. Shpilman, 2010, Molecular genetics and metabolism.

Development and Characterization of High Affinity Leptins and Leptin Antagonists*

Z. Halpern, E. Elinav, E. Boder, 2010, The Journal of Biological Chemistry.

Large-scale preparation of biologically active mouse and rat leptins and their L39A/D40A/F41A muteins which act as potent antagonists.

E. Gussakovsky, A. Gertler, L. Niv-Spector, 2006, Protein expression and purification.

Identification of the hydrophobic strand in the A-B loop of leptin as major binding site III: implications for large-scale preparation of potent recombinant human and ovine leptin antagonists.

M. Taouis, I. Callebaut, B. Herman, 2005, The Biochemical journal.

Preparation and characterization of mouse IL-22 and its four single-amino-acid muteins that act as IL-22 receptor-1 antagonists.

E. Elinav, C. Varol, A. Gertler, 2012, Protein engineering, design & selection : PEDS.

Prolactin affects leptin action in the bovine mammary gland via the mammary fat pad.

S. Mabjeesh, Y. Feuermann, A. Shamay, 2006, The Journal of endocrinology.

Large-scale preparation and characterization of non-pegylated and pegylated superactive ovine leptin antagonist.

A. Gertler, Y. Boisclair, M. Shpilman, 2012, Protein expression and purification.

Preparation of Leptin Antagonists by Site‐Directed Mutagenesis of Human, Ovine, Rat, and Mouse Leptin's Site III

I. Callebaut, J. Djiane, A. Gertler, 2006, Annals of the New York Academy of Sciences.