D. C. Soares

G. Summers, S. Ralston, D. Soares, 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

PLAA Mutations Cause a Lethal Infantile Epileptic Encephalopathy by Disrupting Ubiquitin-Mediated Endolysosomal Degradation of Synaptic Proteins

Mark T. Handley, I. Jackson, R. Ribchester, 2017, American journal of human genetics.

Targeted sequencing of the Paget's disease associated 14q32 locus identifies several missense coding variants in RIN3 that predispose to Paget's disease of bone

S. Ralston, D. Soares, D. Salter, 2015, Human molecular genetics.

missense coding variants in RIN3 that predispose to Paget's disease of bone

S. Ralston, D. Soares, D. Salter, 2015 .

DISC1: Structure, Function, and Therapeutic Potential for Major Mental Illness

D. Porteous, D. Soares, B. Carlyle, 2011, ACS chemical neuroscience.

Explorer DISC 1 : Structure , Function , and Therapeutic Potential for Major Mental Illness

D. Porteous, D. Soares, B. Carlyle, 2011 .

Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations.

Gunnar Houge, Stefan Johansson, Martin S. Taylor, 2014, American journal of human genetics.

Structural Models of Human eEF1A1 and eEF1A2 Reveal Two Distinct Surface Clusters of Sequence Variation and Potential Differences in Phosphorylation

D. Porteous, D. Soares, P. Barlow, 2009, PloS one.

Mutations in PLAA cause a lethal infantile epileptic encephalopathy by disrupting ubiquitin-mediated endolysosomal degradation of synaptic proteins

Mark T. Handley, R. Ribchester, C. Woods, 2017 .

A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells

A. Hinck, T. Le Bihan, A. Ivens, 2017, Nature Communications.

A structurally distinct immunosuppressive TGF-mimic from an intestinal helminth that potently induces murine and human regulatory T cells

A. Hinck, A. Ivens, R. Maizels, 2017 .

Condensin II mutation causes T-cell lymphoma through tissue-specific genome instability

D. Jamieson, B. Ylstra, W. Bickmore, 2016, Genes & development.

HIV-1 Uncoating and Reverse Transcription Require eEF1A Binding to Surface-Exposed Acidic Residues of the Reverse Transcriptase Thumb Domain

D. Harrich, D. Soares, Dongsheng Li, 2018, mBio.

The evolution of TEP1, an exceptionally polymorphic immunity gene in Anopheles gambiae

F. Jiggins, Darren J Obbard, D. Soares, 2008, BMC Evolutionary Biology.

Evolutionary Characterization of the Retinitis Pigmentosa GTPase Regulator Gene.

A. Wright, X. Shu, D. Soares, 2015, Investigative ophthalmology & visual science.

Bioinformatics studies on sequence, structure and functional relationships of proteins involved in the complement system

Dinesh Christopher Soares, D. Soares, D. C. Soares, 2007 .

Structure-based Mapping of DAF Active Site Residues That Accelerate the Decay of C3 Convertases*

D. Hourcade, D. Soares, P. Barlow, 2007, Journal of Biological Chemistry.

NDE1 and NDEL1: twin neurodevelopmental proteins with similar ‘nature’ but different ‘nurture’

W. Hennah, D. Soares, N. Bradshaw, 2013, Biomolecular concepts.

An interrupted beta-propeller and protein disorder: structural bioinformatics insights into the N-terminus of alsin

D. Porteous, D. Soares, P. Barlow, 2009, Journal of molecular modeling.

Large-scale modelling as a route to multiple surface comparisons of the CCP module family.

J. Parkinson, D. Gerloff, D. Soares, 2005, Protein engineering, design & selection : PEDS.

DISC1 genetics, biology and psychiatric illness

D. Soares, J. Millar, P. Thomson, 2013, Frontiers in Biology.

The Mitosis and Neurodevelopment Proteins NDE1 and NDEL1 Form Dimers, Tetramers, and Polymers with a Folded Back Structure in Solution*

Juri Rappsilber, David J. Porteous, Malcolm D. Walkinshaw, 2012, The Journal of Biological Chemistry.

PKA Phosphorylation of NDE1 Is DISC1/PDE4 Dependent and Modulates Its Interaction with LIS1 and NDEL1

D. Porteous, D. Soares, J. Millar, 2011, The Journal of Neuroscience.

PKA Phosphorylation of NDE 1 Is DISC 1 / PDE 4 Dependent and Modulates Its Interaction with LIS 1 and NDEL 1

D. Porteous, D. Soares, J. Millar, 2011 .

Characterization of a novel RP 2-OSTF 1 interaction and its implication for actin remodeling

A. Wittinghofer, T. Hurd, J. Marsh, 2018 .

A t(1;11) translocation linked to schizophrenia and affective disorders gives rise to aberrant chimeric DISC1 transcripts that encode structurally altered, deleterious mitochondrial proteins

David J. Porteous, Walter J. Muir, Elizabeth A. Blackburn, 2012, Human molecular genetics.

Missense Mutations in the Human Nanophthalmos Gene TMEM98 Cause Retinal Defects in the Mouse

S. Cross, I. Jackson, L. Sánchez-Pulido, 2019, bioRxiv.

Detailed analysis of NDEL1 structures and NDE1 homology models

D. Porteous, D. Soares, S. Christie, 2011 .

ARABIDOPSIS CRINKLY4 Function, Internalization, and Turnover Are Dependent on the Extracellular Crinkly Repeat Domainw⃞

Fiona C. Robertson, M. Gifford, D. Soares, 2005, The Plant Cell Online.

Solution Structure of Factor I-like Modules from Complement C7 Reveals a Pair of Follistatin Domains in Compact Pseudosymmetric Arrangement*

J. Bramham, D. Soares, P. Barlow, 2009, The Journal of Biological Chemistry.

Ablation of EYS in zebrafish causes mislocalisation of outer segment proteins, F-actin disruption and cone-rod dystrophy

Fei Liu, Tao Jiang, D. Soares, 2017, Scientific Reports.

Specific Interaction between eEF1A and HIV RT Is Critical for HIV-1 Reverse Transcription and a Potential Anti-HIV Target

D. Harrich, D. Soares, C. Abbott, 2015, PLoS pathogens.

A common variant in the 3′UTR of the GRIK4 glutamate receptor gene affects transcript abundance and protects against bipolar disorder

D. Blackwood, W. Muir, K. McGhee, 2008, Proceedings of the National Academy of Sciences.

A structural organization for the Disrupted in Schizophrenia 1 protein, identified by high-throughput screening, reveals distinctly folded regions, which are bisected by mental illness-related mutations

P. Mas, D. Hart, D. Soares, 2017, The Journal of Biological Chemistry.

RPGR: Its role in photoreceptor physiology, human disease, and future therapies

A. Wright, D. Soares, R. Megaw, 2015, Experimental eye research.

Solution Structure of CCP Modules 10–12 Illuminates Functional Architecture of the Complement Regulator, Factor H

Dmitri I. Svergun, Paul N. Barlow, Christoph Q. Schmidt, 2012, Journal of molecular biology.

Structural Analysis of the C-Terminal Region (Modules 18–20) of Complement Regulator Factor H (FH)

D. Svergun, H. Mertens, D. Soares, 2012, PloS one.

The Central Portion of Factor H (Modules 10–15) Is Compact and Contains a Structurally Deviant CCP Module

D. Svergun, D. Uhrín, A. Rowe, 2010, Journal of molecular biology.

Structure of the N-terminal Region of Complement Factor H and Conformational Implications of Disease-linked Sequence Variations*S⃞

D. Uhrín, M. Pangburn, D. Soares, 2008, Journal of Biological Chemistry.

Disease-associated sequence variations in factor H: a structural biology approach.

M. Pangburn, D. Soares, P. Barlow, 2006, Advances in experimental medicine and biology.

Structural Analysis of the Complement Control Protein (CCP) Modules of GABAB Receptor 1a

Brian O. Smith, D. Uhrín, D. Soares, 2004, Journal of Biological Chemistry.

In silico structure-function analysis of pathological variation in the HSD11B2 gene sequence.

D. Soares, J. Mullins, J. Manning, 2010, Physiological genomics.

Novel pathogenic mutations in C1QTNF5 support a dominant negative disease mechanism in late-onset retinal degeneration

A. Cideciyan, S. Jacobson, A. Lennon, 2017, Scientific Reports.

Pathogenic mutations in retinitis pigmentosa 2 predominantly result in loss of RP2 protein stability in humans and zebrafish

Tao Jiang, X. Shu, D. Soares, 2017, The Journal of Biological Chemistry.

A recurrent de novo mutation in ACTG1 causes isolated ocular coloboma

J. Prendergast, D. Soares, D. Fitzpatrick, 2017, Human mutation.

Complement Control Protein Modules in the Regulators of Complement Activation

D. Soares, P. Barlow, D. C. Soares, 2005 .