Elisabeth A. Zirwes

Development of High-Specificity Fluorescent Probes to Enable Cannabinoid Type 2 Receptor Studies in Living Cells.

W. Guba, E. Carreira, A. Rufer, 2020, Journal of the American Chemical Society.

Highly Selective, Amine-Derived Cannabinoid Receptor 2 Probes.

W. Guba, E. Carreira, U. Grether, 2019, Chemistry.

Diverse chemotypes drive biased signaling by cannabinoid receptors

W. Guba, A. Rufer, D. Veprintsev, 2020, bioRxiv.

Detection of cannabinoid receptor type 2 in native cells and zebrafish with a highly potent, cell-permeable fluorescent probe

H. Spaink, W. Guba, E. Carreira, 2022, Chemical science.

Platform Reagents Enable Synthesis of Ligand-Directed Covalent Probes: Study of Cannabinoid Receptor 2 in Live Cells.

W. Guba, E. Carreira, D. Veprintsev, 2023, Journal of the American Chemical Society.

RG7774 (Vicasinabin), an orally bioavailable cannabinoid receptor 2 (CB2R) agonist, decreases retinal vascular permeability, leukocyte adhesion, and ocular inflammation in animal models

C. Bissantz, F. Fezza, U. Grether, 2024, Frontiers in pharmacology.