James Baker

发表

Optimisation of pharmacokinetic properties to afford an orally bioavailable and selective V1A receptor antagonist.

M. Craighead, Michael Kiczun, A. Lyons, 2011, Bioorganic & medicinal chemistry letters.

The discovery of novel 8-azabicyclo[3.2.1]octan-3-yl)-3-(4-chlorophenyl) propanamides as vasopressin V1A receptor antagonists.

F. Thomson, M. Craighead, G. Wishart, 2011, Bioorganic & medicinal chemistry letters.

Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications.

Duan Liu, M. Altman, Ruojing Yang, 2015, Bioorganic & medicinal chemistry letters.

Pharmacokinetic optimisation of novel indole-2-carboxamide cannabinoid CB1 antagonists.

M. Deehan, G. Wishart, G. Walker, 2011, Bioorganic & medicinal chemistry letters.

Low brain penetrant CB1 receptor agonists for the treatment of neuropathic pain.

S. Boyce, M. Deehan, Robert A. Campbell, 2012, Bioorganic & medicinal chemistry letters.

Design, synthesis, and structure–activity relationships of indole-3-carboxamides as novel water soluble cannabinoid CB1 receptor agonists

R. Morphy, J. Tierney, I. Cumming, 2010 .

Discovery and optimization of 1-(4-(pyridin-2-yl)benzyl)imidazolidine-2,4-dione derivatives as a novel class of selective cannabinoid CB2 receptor agonists.

S. Boyce, M. van der Stelt, J. Oosterom, 2011, Journal of medicinal chemistry.

Synthesis and SAR studies of novel 2-(6-aminomethylaryl-2-aryl-4-oxo-quinazolin-3(4H)-yl)acetamide vasopressin V1b receptor antagonists.

D. Auld, M. Webb, M. Ohlmeyer, 2011, Bioorganic & medicinal chemistry letters.

Identification and optimisation of novel sulfonamide, selective vasopressin V1B receptor antagonists.

F. Thomson, M. Craighead, R. Blackburn-Munro, 2011, Bioorganic & medicinal chemistry letters.

Synthesis and SAR studies of novel 2-(4-oxo-2-aryl-quinazolin-3(4H)-yl)acetamide vasopressin V1b receptor antagonists.

D. Auld, M. Webb, M. Ohlmeyer, 2011, Bioorganic & medicinal chemistry letters.

Design, synthesis, and structure-activity relationship study of conformationally constrained analogs of indole-3-carboxamides as novel CB1 cannabinoid receptor agonists.

G. Walker, Darren Edwards, M. York, 2010, Bioorganic & medicinal chemistry letters.

Design, synthesis, and structure-activity relationships of indole-3-heterocycles as agonists of the CB1 receptor.

M. Deehan, Robert A. Campbell, K. Meyer, 2011, Bioorganic & medicinal chemistry letters.

Discovery of potent and orally bioavailable heterocycle-based cannabinoid CB1 receptor agonists.

James Baker, Stuart Francis, Duncan McArthur, 2011, Bioorganic & medicinal chemistry letters.

Design, synthesis, and structure-activity relationship study of bicyclic piperazine analogs of indole-3-carboxamides as novel cannabinoid CB1 receptor agonists.

Glenn Walker, James Baker, Richard Morphy, 2010, Bioorganic & medicinal chemistry letters.

Identification of N-(1H-pyrazol-4-yl)carboxamide inhibitors of interleukin-1 receptor associated kinase 4: Bicyclic core modifications.

Duan Liu, M. Altman, Ruojing Yang, 2015, Bioorganic & medicinal chemistry letters.

The discovery of novel indole-2-carboxamides as cannabinoid CB(1) receptor antagonists.

M. Deehan, G. Wishart, R. Goodwin, 2011, Bioorganic & medicinal chemistry letters.