J. Le Coq

Examination of the mechanism of human brain aspartoacylase through the binding of an intermediate analogue.

R. Sanishvili, R. Viola, A. Pavlovsky, 2008, Biochemistry.

Characterization of Human Aspartoacylase: the brain enzyme responsible for Canavan disease

R. Viola, J. Le Coq, 2006, Biochemistry.

New insights into FAK structure and function in focal adhesions.

Pilar López Navajas, D. Lietha, J. Le Coq, 2022, Journal of cell science.

Inhibition of both focal adhesion kinase and fibroblast growth factor receptor 2 pathways induces anti-tumor and anti-angiogenic activities.

J. Herbeuval, D. Lietha, C. Garbay, 2014, Cancer letters.

Synthesis of novel diarylamino-1,3,5-triazine derivatives as FAK inhibitors with anti-angiogenic activity.

D. Lietha, C. Garbay, Y. Lepelletier, 2013, Bioorganic & medicinal chemistry letters.

A new layer of phosphoinositide‐mediated allosteric regulation uncovered for SHIP2

C. Alfonso, Pilar López Navajas, D. Lietha, 2021, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Structural basis for interdomain communication in SHIP2 providing high phosphatase activity

D. Lietha, M. Camacho-Artacho, N. Dölker, 2017, eLife.

Purification and preliminary characterization of brain aspartoacylase.

Roger A. Moore, R. Viola, C. R. Faehnle, 2003, Archives of biochemistry and biophysics.

Examination of Key Intermediates in the Catalytic Cycle of Aspartate-β-semialdehyde Dehydrogenase from a Gram-positive Infectious Bacteria*

R. Viola, C. R. Faehnle, Xuying Liu, 2006, Journal of Biological Chemistry.

Allosteric regulation of focal adhesion kinase by PIP₂ and ATP.

F. Gräter, D. Lietha, Jing Zhou, 2015, Biophysical journal.

Conservation of the C-type lectin fold for massive sequence variation in a Treponema diversity-generating retroelement

P. Ghosh, J. Le Coq, 2011, Proceedings of the National Academy of Sciences.

Expression, Purification, Crystallisation and X-ray Crystallographic Analysis of a Truncated Form of Human Src Homology 2 Containing Inositol 5-Phosphatase 2

D. Lietha, Johanne Le Coq, Luis Heredia Gallego, 2016, The Protein Journal.