M. Ruszczycky

发表

Tartrate dehydrogenase reductive decarboxylation: stereochemical generation of diastereotopically deuterated hydroxymethylenes.

V. Anderson, M. Ruszczycky, 2004, Bioorganic chemistry.

Characterization and mechanistic studies of DesII: a radical S-adenosyl-L-methionine enzyme involved in the biosynthesis of TDP-D-desosamine.

Hung‐wen Liu, F. Yan, M. Ruszczycky, 2009, Journal of the American Chemical Society.

Biochemistry: The surprising history of an antioxidant

Hung‐wen Liu, M. Ruszczycky, 2017, Nature.

A fluoro analogue of UDP-α-D-glucuronic acid is an inhibitor of UDP-α-D-apiose/UDP-α-D-xylose synthase.

Hung‐wen Liu, Hua Zhang, M. Ruszczycky, 2011, Chemical communications.

Flavin-enabled reductive and oxidative epoxide ring opening reactions

Hung‐wen Liu, A. Mándi, T. Kurtán, 2022, Nature Communications.

Mechanistic Implications of the Deamination of TDP-4-amino-4-deoxy-d-fucose Catalyzed by the Radical SAM Enzyme DesII.

Hung‐wen Liu, Geng-min Lin, M. Ruszczycky, 2018, Biochemistry.

Theory and Application of the Relationship Between Steady-State Isotope Effects on Enzyme Intermediate Concentrations and Net Rate Constants.

Hung‐wen Liu, M. Ruszczycky, 2017, Methods in enzymology.

Mechanistic studies of the radical S-adenosylmethionine enzyme DesII with TDP-D-fucose.

Hung‐wen Liu, M. Ruszczycky, Sei-hyun Choi, 2015, Angewandte Chemie.

Stoichiometry of the redox neutral deamination and oxidative dehydrogenation reactions catalyzed by the radical SAM enzyme DesII.

Hung‐wen Liu, M. Ruszczycky, Sei-hyun Choi, 2010, Journal of the American Chemical Society.

Identification and Characterization of Enzymes Catalyzing Pyrazolopyrimidine Formation in the Biosynthesis of Formycin A.

Hung‐wen Liu, Yasushi Ogasawara, Shao‐An Wang, 2017, Organic letters.

Role of Asp104 in the SHV β-Lactamase

R. Bonomo, K. Hujer, A. Hujer, 2006, Antimicrobial Agents and Chemotherapy.

Role of Asp104 in the SHV (cid:2) -Lactamase (cid:1)

R. Bonomo, K. Hujer, A. Hujer, 2006 .

An Enzyme-Catalyzed [4+2] Cycloaddition is a Key Step in the Biosynthesis of Spinosyn A

Hung‐wen Liu, Mark W. Ruszczycky, Hak Joong Kim, 2011, Nature.

Measurement of Net Rate Constants from Enzyme Progress Curves without Curve Fitting.

Hung‐wen Liu, M. Ruszczycky, 2019, Biochemistry.

Changes in Regioselectivity of H Atom Abstraction during the Hydroxylation and Cyclization Reactions Catalyzed by Hyoscyamine 6β-Hydroxylase.

Hung‐wen Liu, Richiro Ushimaru, M. Ruszczycky, 2018, Journal of the American Chemical Society.

Evidence for an Enzyme-Catalyzed Rauhut-Currier Reaction during the Biosynthesis of Spinosyn A.

M. Tsai, T. Ko, Hung‐wen Liu, 2021, Journal of the American Chemical Society.

Activation of oxygen nucleophiles in enzyme catalysis.

V. Anderson, M. Harris, Mark W. Ruszczycky, 2006, Chemical reviews.

Studies of 1-Amino-2,2-difluorocyclopropane-1-carboxylic Acid: Mechanism of Decomposition and Inhibition of 1-Aminocyclopropane-1-carboxylic Acid Deaminase.

Hung‐wen Liu, Mark W. Ruszczycky, Huawei Chen, 2015, Organic letters.

Radical SAM enzymes in the biosynthesis of sugar-containing natural products.

Hung‐wen Liu, Yasushi Ogasawara, M. Ruszczycky, 2012, Biochimica et biophysica acta.

Substrate Conformation Correlates with the Outcome of Hyoscyamine 6β-Hydroxylase Catalyzed Oxidation Reactions.

Hung‐wen Liu, Wei‐chen Chang, Yung-nan Liu, 2018, Journal of the American Chemical Society.

Byproduct formation during the biosynthesis of spinosyn A and evidence for an enzymatic interplay to prevent its formation.

S. Hung, Hung‐wen Liu, Teng-Yi Huang, 2021, Tetrahedron.

Natural [4 + 2]-Cyclases.

Hung‐wen Liu, Shao‐An Wang, Byung-sun Jeon, 2017, Chemical reviews.

Nucleophilic Participation of Reduced Flavin Coenzyme in Mechanism of UDP-galactopyranose Mutase*

C. Thibodeaux, Hung‐wen Liu, Wei‐chen Chang, 2011, The Journal of Biological Chemistry.

Mechanistic Investigation of the Radical S-Adenosyl-L-methionine Enzyme DesII Using Fluorinated Analogues.

Hung‐wen Liu, Geng-min Lin, M. Ruszczycky, 2015, Journal of the American Chemical Society.

Radical S-Adenosyl Methionine Enzyme BlsE Catalyzes a Radical-Mediated 1,2-Diol Dehydration during the Biosynthesis of Blasticidin S.

Hung‐wen Liu, Jin-Ming Gao, Binju Wang, 2022, Journal of the American Chemical Society.

Following the electrons: peculiarities in the catalytic cycles of radical SAM enzymes.

Hung‐wen Liu, Mark W. Ruszczycky, Aoshu Zhong, 2018, Natural product reports.

Mechanistic Enzymology of the Radical SAM Enzyme DesII.

Hung‐wen Liu, Mark W. Ruszczycky, M. Ruszczycky, 2015, Israel journal of chemistry.

EPR-kinetic isotope effect study of the mechanism of radical-mediated dehydrogenation of an alcohol by the radical SAM enzyme DesII

Hung‐wen Liu, M. Ruszczycky, Sei-hyun Choi, 2013, Proceedings of the National Academy of Sciences.

Mechanistic studies of the radical S-adenosyl-L-methionine enzyme DesII: EPR characterization of a radical intermediate generated during its catalyzed dehydrogenation of TDP-D-quinovose.

Hung‐wen Liu, S. O. Mansoorabadi, M. Ruszczycky, 2011, Journal of the American Chemical Society.

β-Secondary deuterium equilibrium and kinetic isotope effects on nucleophilic attack by methanol at a carbonyl: Computational estimation of deviation from the rule of the geometric mean

V. Anderson, M. Ruszczycky, 2009 .

Interpretation of V/K isotope effects for enzymatic reactions exhibiting multiple isotopically sensitive steps.

V. Anderson, M. Ruszczycky, 2006, Journal of theoretical biology.

Investigation of the mechanism of the SpnF-catalyzed [4+2]-cycloaddition reaction in the biosynthesis of spinosyn A

J. Patrick, Hung‐wen Liu, D. Russell, 2017, Proceedings of the National Academy of Sciences.

Current developments and challenges in the search for a naturally selected Diels-Alderase.

Hung‐wen Liu, Hak Joong Kim, M. Ruszczycky, 2012, Current opinion in chemical biology.

Characterization of the coformycin biosynthetic gene cluster in Streptomyces kaniharaensis

Hung‐wen Liu, Yasushi Ogasawara, Shao‐An Wang, 2020, Proceedings of the National Academy of Sciences.

HygY Is a Twitch Radical SAM Epimerase with Latent Dehydrogenase Activity Revealed upon Mutation of a Single Cysteine Residue.

Hung‐wen Liu, Aimin Liu, I. Davis, 2021, Journal of the American Chemical Society.

Inhibition of OXA-1 β-Lactamase by Penems

R. Bonomo, K. Hujer, A. Hujer, 2008, Antimicrobial Agents and Chemotherapy.

Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S-Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase.

Hung‐wen Liu, Jiahai Zhou, M. Ruszczycky, 2022, Journal of the American Chemical Society.

Changing Fates of the Substrate Radicals Generated in the Active Sites of the B12-Dependent Radical SAM Enzymes OxsB and AlsB.

Hung‐wen Liu, Aoshu Zhong, Y. Yeh, 2023, Journal of the American Chemical Society.

Role of Asp104 in the SHV beta-lactamase.

R. Bonomo, K. Hujer, A. Hujer, 2006, Antimicrobial agents and chemotherapy.

Distinguishing Concerted versus Stepwise Mechanisms Using Isotope Effects on Isotope Effects.

Hung‐wen Liu, M. Ruszczycky, 2021, Biochemistry.